Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Paresma Patel"'
Autor:
Asma Dilawari, Mirat Shah, Gwynn Ison, Haley Gittleman, Mallorie H. Fiero, Ankit Shah, Salaheldin S. Hamed, Junshan Qiu, Jingyu Yu, Wimolnut Manheng, Tiffany K. Ricks, Rajan Pragani, Arulvathani Arudchandran, Paresma Patel, Shadia Zaman, Arpita Roy, Shyam Kalavar, Soma Ghosh, William F. Pierce, Nam Atiqur. Rahman, Shenghui Tang, Bronwyn D. Mixter, Paul G. Kluetz, Richard Pazdur, Laleh Amiri-Kordestani
Publikováno v:
Clinical Cancer Research.
On November 14, 2022, the U.S. Food and Drug Administration (FDA) granted accelerated approval to mirvetuximab soravtansine-gynx for treatment of adult patients with folate receptor-α (FRα)-positive, platinum-resistant epithelial ovarian, fallopian
Autor:
Udo Rudloff, Craig J. Thomas, Marc Ferrer, Jeffrey Aubé, Steven A. Rogers, Paresma Patel, Jian-kang Jiang, Dandan Li, Astin S. Powers, Holger Pflicke, Hong-Wu Xin, Paul Shinn, Rajarshi Guha, Vivek Shukla, Taylor J. Aiken, Lesley A. Mathews Griner, Yaroslav Teper, Yansong Bian
Suppl. Fig. 1: Procedures for synthesis of NCGC00188382 (Inhibitor#1) Suppl. Fig. 2: qPCR array of 96 stem cell genes from PANC1 adherent and PANC1 spheroids reveal up-regulation of six stem cell genes in organotypic Panc1 spheres. Suppl. Fig. 3: Inh
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a29c837ea26c77693a9c700ef66f4593
https://doi.org/10.1158/1535-7163.22506210.v1
https://doi.org/10.1158/1535-7163.22506210.v1
Autor:
Udo Rudloff, Craig J. Thomas, Marc Ferrer, Jeffrey Aubé, Steven A. Rogers, Paresma Patel, Jian-kang Jiang, Dandan Li, Astin S. Powers, Holger Pflicke, Hong-Wu Xin, Paul Shinn, Rajarshi Guha, Vivek Shukla, Taylor J. Aiken, Lesley A. Mathews Griner, Yaroslav Teper, Yansong Bian
Pancreatic cancer remains an incurable condition. Its progression is driven, in part, by subsets of cancer cells that evade the cytotoxic effects of conventional chemotherapies. These cells are often low-cycling, multidrug resistant, and adopt a stem
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1e21950819e835c195e9bc54f304d464
https://doi.org/10.1158/1535-7163.c.6538326
https://doi.org/10.1158/1535-7163.c.6538326
Autor:
Udo Rudloff, Craig J. Thomas, Marc Ferrer, Jeffrey Aubé, Steven A. Rogers, Paresma Patel, Jian-kang Jiang, Dandan Li, Astin S. Powers, Holger Pflicke, Hong-Wu Xin, Paul Shinn, Rajarshi Guha, Vivek Shukla, Taylor J. Aiken, Lesley A. Mathews Griner, Yaroslav Teper, Yansong Bian
Suppl. Table 1. Origin of cancer cell lines used in this study. Suppl. Table 2. Quantitative HTS screen in PANC1 cells grown as spheroids. Results of full ten concentration drug-response curves of 1,912 individual agents and compounds in PANC1 sphero
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::82e4ba4ea7ca0eeb8db75195a3876a14
https://doi.org/10.1158/1535-7163.22506207.v1
https://doi.org/10.1158/1535-7163.22506207.v1
Autor:
Udo Rudloff, Craig J. Thomas, Marc Ferrer, Jeffrey Aubé, Steven A. Rogers, Paresma Patel, Jian-kang Jiang, Dandan Li, Astin S. Powers, Holger Pflicke, Hong-Wu Xin, Paul Shinn, Rajarshi Guha, Vivek Shukla, Taylor J. Aiken, Lesley A. Mathews Griner, Yaroslav Teper, Yansong Bian
Suppl. Table 1. Origin of cancer cell lines used in this study. Suppl. Table 2. Quantitative HTS screen in PANC1 cells grown as spheroids. Results of full ten concentration drug-response curves of 1,912 individual agents and compounds in PANC1 sphero
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ef7ee27a7001f1e291a06f5655cfed31
https://doi.org/10.1158/1535-7163.22506213
https://doi.org/10.1158/1535-7163.22506213
Autor:
R. Angelo De Claro, Marc R. Theoret, Richard Pazdur, Kirsten B. Goldberg, Adam N. Maung, Sherita McLamore, Anamitro Banerjee, Rakhi Shah, Djelila Mezaache, Paresma Patel, Yuching Yang, Lian Ma, Olanrewaju O. Okusanya, Jonathon Vallejo, Soumya Mitra, Ramadevi Gudi, Ying-Hong Wang, Ruo-Jing Li, Alexei Ionan, Robert Q. Le, Donna Przepiorka
On July 16, 2021, the FDA approved belumosudil, a kinase inhibitor, for adult and pediatric patients 12 years and older with chronic GvHD (cGvHD) after failure of at least two prior lines of systemic therapy. Approval was based on the results of Stud
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5cf5ad9b338cb810d274cde6114ea10c
https://doi.org/10.1158/1078-0432.c.6532340
https://doi.org/10.1158/1078-0432.c.6532340
Autor:
Richard Pazdur, Gideon M. Blumenthal, Ann T. Farrell, Kirsten B. Goldberg, Jiang Liu, Anamitro Banerjee, Christopher M. Sheth, Stacy S. Shord, Yuan Li Shen, Donna Przepiorka, David A. Bateman, Gerlie Gieser, Kumar G. Janoria, Wentao Fu, Paresma Patel, Michael L. Manning, Liang Li, Xin Gao, Aviva C. Krauss
On August 3, 2017, the FDA granted regular approval to Vyxeos (also known as CPX-351; Jazz Pharmaceuticals), a liposomal formulation of daunorubicin and cytarabine in a fixed combination, for the treatment of adults with newly diagnosed therapy-relat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::54674ded12a4d242af56ef0583b02f7c
https://doi.org/10.1158/1078-0432.c.6528362
https://doi.org/10.1158/1078-0432.c.6528362
Autor:
Richard Pazdur, Gideon M. Blumenthal, Ann T. Farrell, Kirsten B. Goldberg, Jiang Liu, Anamitro Banerjee, Christopher M. Sheth, Stacy S. Shord, Yuan Li Shen, Donna Przepiorka, David A. Bateman, Gerlie Gieser, Kumar G. Janoria, Wentao Fu, Paresma Patel, Michael L. Manning, Liang Li, Xin Gao, Aviva C. Krauss
Supplemental Table S1: Grouped Terms for Adverse Reactions on Study 301
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2a4c8d39e6c98e8ee1b0d9194c689465
https://doi.org/10.1158/1078-0432.22472897.v1
https://doi.org/10.1158/1078-0432.22472897.v1
Autor:
Richard Pazdur, Gideon M. Blumenthal, Ann T. Farrell, Kirsten B. Goldberg, Jiang Liu, Anamitro Banerjee, Christopher M. Sheth, Stacy S. Shord, Yuan Li Shen, Donna Przepiorka, David A. Bateman, Gerlie Gieser, Kumar G. Janoria, Wentao Fu, Paresma Patel, Michael L. Manning, Liang Li, Xin Gao, Aviva C. Krauss
Supplemental Table 2: Prolonged Cytopenia on Study 301
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1da6dffa5a43ed01333b3429062bf641
https://doi.org/10.1158/1078-0432.22472894
https://doi.org/10.1158/1078-0432.22472894
Autor:
Ira Pastan, Craig Thomas, Pinar Ormanoglu, Marco Prunotto, Paresma Patel, Scott Martin, David J. FitzGerald, Fatima Ali-Rahmani
Recombinant immunotoxins (RIT) have been highly successful in cancer therapy due, in part, to the high cancer-specific expression of cell surface antigens such as mesothelin, which is overexpressed in mesothelioma, ovarian, lung, breast, and pancreat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4af27416051cb4f6b6e6defa1a2e88e3
https://doi.org/10.1158/0008-5472.c.6508197.v1
https://doi.org/10.1158/0008-5472.c.6508197.v1