Zobrazeno 1 - 10
of 59
pro vyhledávání: '"Paresh Prajapati"'
Autor:
Hemendra J. Vekaria, Olivia J. Kalimon, Paresh Prajapati, Gopal V. Velmurugan, Patrick G. Sullivan
Publikováno v:
Frontiers in Molecular Biosciences, Vol 11 (2024)
Mitochondrial function analysis is a well-established method used in preclinical and clinical investigations to assess pathophysiological changes in various disease states, including traumatic brain injury (TBI). Although there are multiple approache
Externí odkaz:
https://doaj.org/article/37f7e14b817c4d12a5b5b40145968e8b
Autor:
Olivia J. Kalimon, Hemendra J. Vekaria, Paresh Prajapati, Sydney L. Short, W. Brad Hubbard, Patrick G. Sullivan
Publikováno v:
Life, Vol 14, Iss 8, p 961 (2024)
Current literature finds females have improved outcomes over their male counterparts after severe traumatic brain injury (TBI), while the opposite seems to be true for mild TBI. This begs the question as to what may be driving these sex differences a
Externí odkaz:
https://doaj.org/article/86fa9c68ca5d49339128bb6c6eece016
Autor:
Gopal V. Velmurugan, W. Brad Hubbard, Paresh Prajapati, Hemendra J. Vekaria, Samir P. Patel, Alexander G. Rabchevsky, Patrick G. Sullivan
Publikováno v:
Cells, Vol 12, Iss 10, p 1445 (2023)
The brain undergoes oxidative stress and mitochondrial dysfunction following physiological insults such as Traumatic brain injury (TBI), ischemia-reperfusion, and stroke. Pharmacotherapeutics targeting mitochondria (mitoceuticals) against oxidative s
Externí odkaz:
https://doaj.org/article/9f94aa251cc2430e9f7a742e04917022
Autor:
Wang-Xia Wang, Paresh Prajapati, Hemendra J Vekaria, Malinda Spry, Amber L Cloud, Patrick G Sullivan, Joe E Springer
Publikováno v:
Neural Regeneration Research, Vol 16, Iss 3, Pp 514-522 (2021)
MicroRNAs (miRNAs) are small non-coding RNA molecules that regulate post-transcriptional gene expression and contribute to all aspects of cellular function. We previously reported that the activities of several mitochondria-enriched miRNAs regulating
Externí odkaz:
https://doaj.org/article/2942397e0bfa455292d0163fc9a85030
Autor:
Dhanendra Tomar, Lakshmi Sripada, Paresh Prajapati, Rochika Singh, Arun Kumar Singh, Rajesh Singh
Publikováno v:
PLoS ONE, Vol 7, Iss 11, p e48662 (2012)
TNF induced nuclear factor kappa B (NF-κB) is one of the central signaling pathways that plays a critical role in carcinogenesis and inflammatory diseases. Post-translational modification through ubiquitin plays important role in the regulation of t
Externí odkaz:
https://doaj.org/article/72188d5d744048df80a7a001d59cb70a
Autor:
Lakshmi Sripada, Dhanendra Tomar, Paresh Prajapati, Rochika Singh, Arun Kumar Singh, Rajesh Singh
Publikováno v:
PLoS ONE, Vol 7, Iss 9, p e44873 (2012)
Mitochondria are one of the central regulators of many cellular processes beyond its well established role in energy metabolism. The inter-organellar crosstalk is critical for the optimal function of mitochondria. Many nuclear encoded proteins and RN
Externí odkaz:
https://doaj.org/article/61d2ee6ae0fa4661ab317a4cb65f8849
Autor:
Paresh Prajapati, Shyam Mehra, Navdeep Singh, Gurkirat Singh Sidhu, Prabhjot Kaur, Rupali, Tanvir Kaur Sidhu
Publikováno v:
Adesh University Journal of Medical Sciences & Research. 3:25-33
Objectives: The objectives of the study were (1) to develop and validate a structured module for teaching family study skills through simulation to undergraduate medical students, (2) to train the undergraduate medical students using the module, (3)
Autor:
Shyam Mehra, Tanvir Kaur Sidhu, Gurkirat Singh Sidhu, Sourabh Paul, Paresh Prajapati, Varun Malhotra
Publikováno v:
International Journal of Medicine and Public Health. 11:118-123
Publikováno v:
Molecular Neurobiology
The mitochondria-associated endoplasmic reticulum (ER) membranes (MAMs) are specific ER domains that contact the mitochondria and function to facilitate communication between ER and mitochondria. Disruption of contact between the mitochondria and ER
Publikováno v:
Cellular and molecular neurobiology. 43(1)
Sex is a key biological variable in traumatic brain injury (TBI) and plays a significant role in neuroinflammatory responses. However, the molecular mechanisms contributing to this sexually dimorphic neuroinflammatory response remain elusive. Here we