Zobrazeno 1 - 10
of 22
pro vyhledávání: '"Paresh K. Patel"'
Publikováno v:
Heliyon, Vol 9, Iss 5, Pp e15644- (2023)
Angiotensin converting enzyme 2 (ACE2) is a homolog of ACE (a transmembrane bound dipeptidyl peptidase enzyme). ACE2 converts angiotensinogen to the heptapeptide angiotensin-(1–7). ACE2 and its product, angiotensin-(1–7), have counteracting effec
Externí odkaz:
https://doaj.org/article/1172f2967e8a4510882b9ea64d02e2df
Publikováno v:
Journal of Liquid Chromatography & Related Technologies. 45:107-119
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8f16e09f7024582d846ad7a0f1168b6a
https://doi.org/10.1080/10826076.2022.2161573
https://doi.org/10.1080/10826076.2022.2161573
Autor:
Hardik G. Bhatt, Paresh K. Patel
Publikováno v:
Current HIV Research. 19:154-171
Background: Inhibition of HIV-I protease enzyme is a strategic step for providing better treatment in retrovirus infections, which avoids resistance and possesses less toxicity. Objectives: In the course of our research to discover new and potent pro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b0cff69e003cbf704e5a4786e4c02ccf
https://doi.org/10.2174/1570162x18666201119143457
https://doi.org/10.2174/1570162x18666201119143457
Publikováno v:
Advances in Traditional Medicine.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::30957efc5923d05a7a3a2fcb10853a00
https://doi.org/10.1007/s13596-022-00646-2
https://doi.org/10.1007/s13596-022-00646-2
Publikováno v:
Chemical Data Collections. 41:100923
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::afb7ac53815e7415aa3f52aac3fd40dd
https://doi.org/10.1016/j.cdc.2022.100923
https://doi.org/10.1016/j.cdc.2022.100923
Autor:
Erik De Clercq, Kishor H. Chikhalia, Paresh K. Patel, Dharmesh H. Mahajan, Christophe Pannecouque, Parimal A. Parikh, Girish Mehta, Rahul V. Patel
Publikováno v:
Journal of Heterocyclic Chemistry. 51:1641-1658
Some new quinolone condensed s-triazine derivatives endowed with different heterocycles and 4-aminobenzonitrile moiety has been synthesized and examined for their bioactivities against eight bacteria (Staphylococcus aureus, Bacillus cereus, Escherich
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9d36f585da51603928f5a9a9f75d2965
https://doi.org/10.1002/jhet.1769
https://doi.org/10.1002/jhet.1769
Publikováno v:
Current Computer Aided-Drug Design. 9:433-445
This study investigated 3D quantitative structure–activity relationships (QSAR) for a range of substituted benzimidazole derivatives as AngII-AT 1 receptor antagonists by comparative molecular field analysis (CoMFA) and comparative molecular simila
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9341f2596043c22523f7d934969f552f
https://doi.org/10.2174/15734099113099990028
https://doi.org/10.2174/15734099113099990028
Autor:
Hardik G. Bhatt, J. Jalu, Nirzari Gupta, Chetan Chintha, Manjunath Ghate, Vivek K. Vyas, Paresh K. Patel
Publikováno v:
SAR and QSAR in Environmental Research. 24:519-551
SGLT2 has become a target of therapeutic interest in diabetes research. CoMFA and CoMSIA studies were performed on C-aryl glucoside SGLT2 inhibitors (180 analogues) as potential anti-diabetic agents. Three different alignment strategies were used for
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::789d22725103a4aec3f2327946100189
https://doi.org/10.1080/1062936x.2012.751553
https://doi.org/10.1080/1062936x.2012.751553
Publikováno v:
European Journal of Medicinal Chemistry. 53:41-51
To affiliate multiple bioactivities in a compact heteronuclei, two series of benzimidazole based 1,3,4-oxadiazoles were synthesized and assessed in vitro for their efficacy as antimicrobial agents against eight bacteria (Staphylococcus aureus, Bacill
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e071f3b32f5dae48ddcbee5bbd0de3cb
https://doi.org/10.1016/j.ejmech.2012.03.033
https://doi.org/10.1016/j.ejmech.2012.03.033
Autor:
Kishor H. Chikhalia, Rahul V. Patel, Girish Mehta, Parimal A. Parikh, Dharmesh H. Mahajan, Paresh K. Patel
Publikováno v:
Medicinal Chemistry Research. 21:3182-3194
In this article, synthesis of a library of trisubstituted s-triazines, which, in addition to 4-amino-benzonitrile, contain 4-hydroxy-N-methylquinolin-2(1H)-one as well as substituted aliphatic amines condensed to C-6 position of s-triazinyl core is d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::601e78b60ca772c56a39410e82773e5c
https://doi.org/10.1007/s00044-011-9849-0
https://doi.org/10.1007/s00044-011-9849-0