Zobrazeno 1 - 10
of 58
pro vyhledávání: '"Paresh A Malhotra"'
Autor:
Martina Del Giovane, Michael C. B. David, Magdalena A. Kolanko, Anastasia Gontsarova, Thomas Parker, Adam Hampshire, David J. Sharp, Paresh A. Malhotra, Christopher Carswell
Publikováno v:
Frontiers in Neuroscience, Vol 18 (2024)
Identifying disease-specific imaging features of idiopathic Normal Pressure Hydrocephalus (iNPH) is crucial to develop accurate diagnoses, although the abnormal brain anatomy of patients with iNPH creates challenges in neuroimaging analysis. We quant
Externí odkaz:
https://doaj.org/article/99445b8a50d743b5972fb3cdcfb00404
Autor:
Elena Olgiati, Ines R. Violante, Shuler Xu, Toby G. Sinclair, Lucia M. Li, Jennifer N. Crow, Marianna E. Kapsetaki, Roberta Calvo, Korina Li, Meenakshi Nayar, Nir Grossman, Maneesh C. Patel, Richard J.S. Wise, Paresh A. Malhotra
Publikováno v:
NeuroImage: Clinical, Vol 42, Iss , Pp 103599- (2024)
Right hemisphere stroke patients frequently present with a combination of lateralised and non-lateralised attentional deficits characteristic of the neglect syndrome. Attentional deficits are associated with poor functional outcome and are challengin
Externí odkaz:
https://doaj.org/article/11f503e6bcf7478e81ad9903e4d2340c
Autor:
Karen Hoang, Hilary Watt, Mara Golemme, Richard J. Perry, Craig Ritchie, Danielle Wilson, James Pickett, Chris Fox, Robert Howard, Paresh A. Malhotra
Publikováno v:
Trials, Vol 23, Iss 1, Pp 1-13 (2022)
Abstract Background Guanfacine is a α2A adrenergic receptor agonist approved for treating attention deficit hyperactivity disorder (ADHD). It is thought to act via postsynaptic receptors in the prefrontal cortex, modulating executive functions inclu
Externí odkaz:
https://doaj.org/article/5392fbb433a4452d9f1ef8fe7d617c09
Autor:
Marianna Inglese, Neva Patel, Kristofer Linton-Reid, Flavia Loreto, Zarni Win, Richard J. Perry, Christopher Carswell, Matthew Grech-Sollars, William R. Crum, Haonan Lu, Paresh A. Malhotra, the Alzheimer’s Disease Neuroimaging Initiative, Eric O. Aboagye
Publikováno v:
Communications Medicine, Vol 2, Iss 1, Pp 1-16 (2022)
Inglese et al. develop a predictive model that computes multi-regional statistical morpho-functional mesoscopic traits from T1-weighted magnetic resonance imaging scans. Their model reliably discriminates people with Alzheimer’s disease-related pat
Externí odkaz:
https://doaj.org/article/516c8e439e694aad9272b31dd5159e63
Autor:
Michael C B David, Magdalena Kolanko, Martina Del Giovane, Helen Lai, Jessica True, Emily Beal, Lucia M Li, Ramin Nilforooshan, Payam Barnaghi, Paresh A Malhotra, Helen Rostill, David Wingfield, Danielle Wilson, Sarah Daniels, David J Sharp, Gregory Scott
Publikováno v:
JMIR Aging, Vol 6, p e43777 (2023)
BackgroundInternet of Things (IoT) technology enables physiological measurements to be recorded at home from people living with dementia and monitored remotely. However, measurements from people with dementia in this context have not been previously
Externí odkaz:
https://doaj.org/article/9d853422e9e340b193627029624f910d
Autor:
Michael David, Paresh A. Malhotra
Publikováno v:
Annals of Clinical and Translational Neurology, Vol 9, Iss 4, Pp 582-596 (2022)
Abstract There is clear, early noradrenergic dysfunction in Alzheimer's disease. This is likely secondary to pathological tau deposition in the locus coeruleus, the pontine nucleus that produces and releases noradrenaline, prior to involvement of cor
Externí odkaz:
https://doaj.org/article/026432796c90421394b290f4ff917fa2
Autor:
Benjamin Tari, Michael Ben Yehuda, Axel Anders Stefan Laurell, Karen Ritchie, Yves Dauvilliers, Craig Ritchie, Brian Lawlor, Lorina Naci, Graciela Muniz Terrera, Paresh A. Malhotra, Tam Watermeyer, Robert Dudas, Benjamin R. Underwood, John T. O’Brien, Vanessa Raymont, Ivan Koychev
IntroductionAs the global population ages, the economic, societal, and personal burdens associated with worsening cognition and dementia onset are growing. It is therefore becoming ever more critical to understand the factors associated with cognitiv
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::da4917a5788aa30ff196d650a5d63dbd
https://doi.org/10.1101/2023.05.18.23290160
https://doi.org/10.1101/2023.05.18.23290160
Autor:
Serena Verdi, Flavia Loreto, Seyed Mostafa Kia, Aleksandar Duvnjak, Haneen Hakeem, Richard J Perry, Zarni Win, Neva Patel, Jonathan M Schott, Andre F Marquand, Paresh A Malhotra, James H Cole
Publikováno v:
Alzheimer's & Dementia. 18
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2f279cc2c099fd2996c2a001783209f4
https://doi.org/10.1002/alz.065489
https://doi.org/10.1002/alz.065489
Autor:
Michael C B David, Martina Del Giovane, Kathy Y Liu, Benjamin Gostick, James Benedict Rowe, Imafidon Oboh, Robert Howard, Paresh A Malhotra
BackgroundDysfunction of the locus coeruleus-noradrenergic system occurs early in Alzheimer’s disease, contributing to cognitive and neuropsychiatric symptoms in some patients. This system offers a potential therapeutic target, although noradrenerg
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2370b488e09d60b4f598f786953c8e5c
Autor:
Marianna, Inglese, Neva, Patel, Kristofer, Linton-Reid, Flavia, Loreto, Zarni, Win, Richard J, Perry, Christopher, Carswell, Matthew, Grech-Sollars, William R, Crum, Haonan, Lu, Paresh A, Malhotra, Gail, Li
Alzheimer's disease, the most common cause of dementia, causes a progressive and irreversible deterioration of cognition that can sometimes be difficult to diagnose, leading to suboptimal patient care.We developed a predictive model that computes mul
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::67aff9a1a3ef401d67561c90b2cfb339
http://hdl.handle.net/10044/1/97726
http://hdl.handle.net/10044/1/97726