Zobrazeno 1 - 10 of 46 pro vyhledávání: '"Pardo ID"'
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Akademický článek
Tento výsledek nelze pro nepřihlášené uživatele zobrazit.
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3
Akademický článek
Dorsal root ganglion toxicity after AAV intra-CSF delivery of a RNAi expression construct into nonhuman primates and mice.
Autor: Hawley ZCE; Biogen, Cambridge, Massachusetts, United States of America., Pardo ID; Biogen, Cambridge, Massachusetts, United States of America., Cao S; Biogen, Cambridge, Massachusetts, United States of America., Zavodszky MI; Biogen, Cambridge, Massachusetts, United States of America., Casey F; Biogen, Cambridge, Massachusetts, United States of America., Ferber K; Biogen, Cambridge, Massachusetts, United States of America., Luo Y; Biogen, Cambridge, Massachusetts, United States of America., Hana S; Biogen, Cambridge, Massachusetts, United States of America., Chen SK; Biogen, Cambridge, Massachusetts, United States of America., Doherty J; Biogen, Cambridge, Massachusetts, United States of America., Costa R; Biogen, Cambridge, Massachusetts, United States of America., Cullen P; Biogen, Cambridge, Massachusetts, United States of America., Liu Y; Biogen, Cambridge, Massachusetts, United States of America., Carlile TM; Biogen, Cambridge, Massachusetts, United States of America., Chowdhury T; Biogen, Cambridge, Massachusetts, United States of America., Doyle B; Biogen, Cambridge, Massachusetts, United States of America., Clarner P; Biogen, Cambridge, Massachusetts, United States of America., Mangaudis K; Biogen, Cambridge, Massachusetts, United States of America., Guilmette E; Biogen, Cambridge, Massachusetts, United States of America., Bourque S; Biogen, Cambridge, Massachusetts, United States of America., Koske D; Biogen, Cambridge, Massachusetts, United States of America., Nadella MVP; Biogen, Cambridge, Massachusetts, United States of America., Trapa P; Biogen, Cambridge, Massachusetts, United States of America., Hawes ML; Charter Preclinical Services, Hudson, Massachusetts, United States of America., Raitcheva D; Biogen, Cambridge, Massachusetts, United States of America. Electronic address: denitza.raitcheva@gmail.com., Lo SC; Biogen, Cambridge, Massachusetts, United States of America. Electronic address: joyce.lo@biogen.com.
Publikováno v: Molecular therapy : the journal of the American Society of Gene Therapy [Mol Ther] 2024 Nov 19. Date of Electronic Publication: 2024 Nov 19.
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4
Akademický článek
Letters or not, here we come! A communal perspective on credentials needed for a productive career in veterinary pathology.
Autor: Pardo ID; Biogen Inc., Cambridge, MA, USA., Langohr IM; Sanofi, Cambridge, MA, USA., Cole P; Zoetis Inc., Kalamazoo, MI, USA., Knoblaugh SE; College of Veterinary Medicine, The Ohio State University, Columbus, OH, USA., Luong R; IDEXX Laboratories, Inc., Westbrook, ME, USA., Mansfield K; Novartis Biomedical Research, Cambridge, MA, USA., Mejia A; University of Wisconsin-Madison, Madison, WI, USA., Meseck E; Novartis Pharmaceuticals Corporation, East Hanover, NJ, USA., Miller AD; College of Veterinary Medicine, Cornell University, Ithaca NY, USA., Penraat K; Novartis Biomedical Research, Cambridge, MA, USA., Pillatzki A; South Dakota State University, Brookings, SD, USA., Bolon B; GEMpath, Inc., Longmont, CO, USA.
Publikováno v: Veterinary pathology [Vet Pathol] 2024 Nov; Vol. 61 (6), pp. 870-873. Date of Electronic Publication: 2024 Aug 20.
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5
Akademický článek
Scientific and Regulatory Policy Committee Technical Review: Biology and Pathology of Ganglia in Animal Species Used for Nonclinical Safety Testing.
Autor: Bennet BM; Magenta Therapeutics, Cambridge, Massachusetts, USA., Pardo ID; Biogen, Cambridge, Massachusetts, USA., Assaf BT; Sanofi, Cambridge, Massachusetts, USA., Buza E; University of Pennsylvania, Philadelphia, Pennsylvania, USA., Cramer SD; StageBio, Frederick, Maryland, USA., Crawford LK; University of Wisconsin-Madison, Madison, Wisconsin, USA., Engelhardt JA; Ionis Pharmaceuticals, Carlsbad, California, USA., Galbreath EJ; Independent Consultant, Lexington, Massachusetts, USA., Grubor B; Biogen, Cambridge, Massachusetts, USA., Morrison JP; Charles River Laboratories, Inc., Shrewsbury, Massachusetts, USA., Osborne TS; Novartis Pharmaceuticals, East Hanover, New Jersey, USA., Sharma AK; Labcorp Drug Development, Madison, Wisconsin, USA., Bolon B; GEMpath Inc., Longmont, Colorado, USA.
Publikováno v: Toxicologic pathology [Toxicol Pathol] 2023 Jul; Vol. 51 (5), pp. 278-305.
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6
Akademický článek
Scientific and Regulatory Policy Committee Points to Consider: Sampling, Processing, Evaluation, Interpretation, and Reporting of Test Article-Related Ganglion Pathology for Nonclinical Toxicity Studies.
Autor: Bennet BM; Magenta Therapeutics, Cambridge, Massachusetts, USA., Pardo ID; Biogen, Cambridge, Massachusetts, USA., Assaf BT; Sanofi, Cambridge, Massachusetts, USA., Buza E; University of Pennsylvania, Gene Therapy Program, Philadelphia, Pennsylvania, USA., Cramer S; StageBio, Frederick, Maryland, USA., Crawford LK; University of Wisconsin-Madison, School of Veterinary Medicine, Madison, Wisconsin, USA., Engelhardt JA; Ionis Pharmaceuticals, Carlsbad, California, USA., Grubor B; Biogen, Cambridge, Massachusetts, USA., Morrison JP; Charles River Laboratories, Inc., Shrewsbury, Massachusetts, USA., Osborne TS; Novartis Pharmaceuticals, East Hanover, New Jersey, USA., Sharma AK; Labcorp Drug Development, Madison, Wisconsin, USA., Bolon B; GEMpath Inc., Longmont, Colorado, USA.
Publikováno v: Toxicologic pathology [Toxicol Pathol] 2023 Jun; Vol. 51 (4), pp. 176-204. Date of Electronic Publication: 2023 Jul 25.
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7
Akademický článek
A Technical Guide to Sampling the Beagle Dog Nervous System for General Toxicity and Neurotoxicity Studies.
Autor: Palazzi X; Pfizer Inc., Groton, Connecticut, USA., Pardo ID; Biogen, Cambridge, Massachusetts, USA., Ritenour H; Pfizer Inc., Groton, Connecticut, USA., Rao DB; Greenfield Pathology Services, Inc., Greenfield, Indiana, USA., Bolon B; GEMpath, Inc., Longmont, Colorado, USA., Garman RH; Consultants in Veterinary Pathology, Inc., Murrysville, Pennsylvania, USA.
Publikováno v: Toxicologic pathology [Toxicol Pathol] 2022 Jun; Vol. 50 (4), pp. 432-465. Date of Electronic Publication: 2022 Jun 22.
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8
Akademický článek
Circulating neurofilament light chain as a promising biomarker of AAV-induced dorsal root ganglia toxicity in nonclinical toxicology species.
Autor: Fader KA; Pfizer Worldwide Research, Development and Medical, Drug Safety Research and Development, Groton, CT 06340, USA., Pardo ID; Biogen, Cambridge, MA 02142, USA., Kovi RC; Pfizer Worldwide Research, Development and Medical, Drug Safety Research and Development, Pfizer Inc., 300 Technology Square, Cambridge, MA 02139, USA., Somps CJ; Pfizer Worldwide Research, Development and Medical, Drug Safety Research and Development, Groton, CT 06340, USA., Wang HH; Pfizer Worldwide Research, Development and Medical, Drug Safety Research and Development, Pfizer Inc., 300 Technology Square, Cambridge, MA 02139, USA., Vaidya VS; Pfizer Worldwide Research, Development and Medical, Drug Safety Research and Development, Pfizer Inc., 300 Technology Square, Cambridge, MA 02139, USA., Ramaiah SK; Pfizer Worldwide Research, Development and Medical, Drug Safety Research and Development, Pfizer Inc., 300 Technology Square, Cambridge, MA 02139, USA., Sirivelu MP; Pfizer Worldwide Research, Development and Medical, Drug Safety Research and Development, Pfizer Inc., 300 Technology Square, Cambridge, MA 02139, USA.
Publikováno v: Molecular therapy. Methods & clinical development [Mol Ther Methods Clin Dev] 2022 Mar 28; Vol. 25, pp. 264-277. Date of Electronic Publication: 2022 Mar 28 (Print Publication: 2022).
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9
Akademický článek
Biodistribution and Tolerability of AAV-PHP.B-CBh- SMN1 in Wistar Han Rats and Cynomolgus Macaques Reveal Different Toxicologic Profiles.
Autor: Palazzi X; Drug Safety Research and Development, Pfizer Worldwide Research Development and Medicine, Groton, Connecticut, USA., Pardo ID; Drug Safety Research and Development, Pfizer Worldwide Research Development and Medicine, Groton, Connecticut, USA., Sirivelu MP; Drug Safety Research and Development, Pfizer Worldwide Research Development and Medicine, Cambridge, Massachusetts, USA., Newman L; Drug Safety Research and Development, Pfizer Worldwide Research Development and Medicine, Groton, Connecticut, USA., Kumpf SW; Drug Safety Research and Development, Pfizer Worldwide Research Development and Medicine, Groton, Connecticut, USA., Qian J; Drug Safety Research and Development, Pfizer Worldwide Research Development and Medicine, Groton, Connecticut, USA., Franks T; Drug Safety Research and Development, Pfizer Worldwide Research Development and Medicine, Groton, Connecticut, USA., Lopes S; Drug Safety Research and Development, Pfizer Worldwide Research Development and Medicine, Groton, Connecticut, USA., Liu J; Drug Safety Research and Development, Pfizer Worldwide Research Development and Medicine, Groton, Connecticut, USA., Monarski L; Drug Safety Research and Development, Pfizer Worldwide Research Development and Medicine, Groton, Connecticut, USA., Casinghino S; Drug Safety Research and Development, Pfizer Worldwide Research Development and Medicine, Groton, Connecticut, USA., Ritenour C; Drug Safety Research and Development, Pfizer Worldwide Research Development and Medicine, Groton, Connecticut, USA., Ritenour H; Drug Safety Research and Development, Pfizer Worldwide Research Development and Medicine, Groton, Connecticut, USA., Dubois C; Drug Safety Research and Development, Pfizer Worldwide Research Development and Medicine, Groton, Connecticut, USA., Olson J; Drug Safety Research and Development, Pfizer Worldwide Research Development and Medicine, Groton, Connecticut, USA., Graves J; Drug Safety Research and Development, Pfizer Worldwide Research Development and Medicine, Groton, Connecticut, USA., Alexander KE; Drug Safety Research and Development, Pfizer Worldwide Research Development and Medicine, Groton, Connecticut, USA., Coskran T; Drug Safety Research and Development, Pfizer Worldwide Research Development and Medicine, Groton, Connecticut, USA., Lanz TA; Drug Safety Research and Development, Pfizer Worldwide Research Development and Medicine, Groton, Connecticut, USA., Brady J; Drug Safety Research and Development, Pfizer Worldwide Research Development and Medicine, Cambridge, Massachusetts, USA., McCarty D; Rare Diseases Research Unit, Pfizer Worldwide Research Development and Medicine, Cambridge, Massachusetts, USA., Suryanarayan S; Rare Diseases Research Unit, Pfizer Worldwide Research Development and Medicine, Cambridge, Massachusetts, USA., Whiteley LO; Drug Safety Research and Development, Pfizer Worldwide Research Development and Medicine, Cambridge, Massachusetts, USA.
Publikováno v: Human gene therapy [Hum Gene Ther] 2022 Feb; Vol. 33 (3-4), pp. 175-187.
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10
Akademický článek
Increases in GFAP immunoreactive astrocytes in the cerebellar molecular layer of young adult CBA/J mice.
Autor: Tyszkiewicz C; Comparative Medicine, Worldwide Research, Development and Medical, Pfizer Inc, MS 8274-1359, PGRD, Eastern Point Road, Groton, CT, 06340, USA., Pardo ID; Global Pathology and Investigative Toxicology, Pfizer Inc, Groton, CT, 06340, USA., Ritenour HN; Global Pathology and Investigative Toxicology, Pfizer Inc, Groton, CT, 06340, USA., Liu CN; Comparative Medicine, Worldwide Research, Development and Medical, Pfizer Inc, MS 8274-1359, PGRD, Eastern Point Road, Groton, CT, 06340, USA. chang-ning.liu@pfizer.com., Somps C; Global Pathology and Investigative Toxicology, Pfizer Inc, Groton, CT, 06340, USA.
Publikováno v: Laboratory animal research [Lab Anim Res] 2021 Aug 28; Vol. 37 (1), pp. 24. Date of Electronic Publication: 2021 Aug 28.
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