Zobrazeno 1 - 10
of 299
pro vyhledávání: '"Pardis C. Sabeti"'
Investigating the etiologies of non-malarial febrile illness in Senegal using metagenomic sequencing
Autor:
Zoë C. Levine, Aita Sene, Winnie Mkandawire, Awa B. Deme, Tolla Ndiaye, Mouhamad Sy, Amy Gaye, Younouss Diedhiou, Amadou M. Mbaye, Ibrahima M. Ndiaye, Jules Gomis, Médoune Ndiop, Doudou Sene, Marietou Faye Paye, Bronwyn L. MacInnis, Stephen F. Schaffner, Daniel J. Park, Aida S. Badiane, Andres Colubri, Mouhamadou Ndiaye, Ngayo Sy, Pardis C. Sabeti, Daouda Ndiaye, Katherine J. Siddle
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-13 (2024)
Abstract The worldwide decline in malaria incidence is revealing the extensive burden of non-malarial febrile illness (NMFI), which remains poorly understood and difficult to diagnose. To characterize NMFI in Senegal, we collected venous blood and cl
Externí odkaz:
https://doaj.org/article/957ca092e5424d709fdd6773c6970ee0
Autor:
Judith U. Oguzie, Brittany A. Petros, Paul E. Oluniyi, Samar B. Mehta, Philomena E. Eromon, Parvathy Nair, Opeoluwa Adewale-Fasoro, Peace Damilola Ifoga, Ikponmwosa Odia, Andrzej Pastusiak, Otitoola Shobi Gbemisola, John Oke Aiyepada, Eghosasere Anthonia Uyigue, Akhilomen Patience Edamhande, Osiemi Blessing, Michael Airende, Christopher Tomkins-Tinch, James Qu, Liam Stenson, Stephen F. Schaffner, Nicholas Oyejide, Nnenna A. Ajayi, Kingsley Ojide, Onwe Ogah, Chukwuyem Abejegah, Nelson Adedosu, Oluwafemi Ayodeji, Ahmed A. Liasu, Sylvanus Okogbenin, Peter O. Okokhere, Daniel J. Park, Onikepe A. Folarin, Isaac Komolafe, Chikwe Ihekweazu, Simon D. W. Frost, Ethan K. Jackson, Katherine J. Siddle, Pardis C. Sabeti, Christian T. Happi
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-14 (2023)
Abstract Effective infectious disease surveillance in high-risk regions is critical for clinical care and pandemic preemption; however, few clinical diagnostics are available for the wide range of potential human pathogens. Here, we conduct unbiased
Externí odkaz:
https://doaj.org/article/cbd604626406414f96c0326f8208d9a7
Autor:
Sayf Al-Deen Hassouneh, Alexa Trujillo, Sobur Ali, Eleonora Cella, Catherine Johnston, Katherine C. DeRuff, Pardis C. Sabeti, Taj Azarian
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-7 (2023)
Abstract Viral genomic surveillance has been integral in the global response to the SARS-CoV-2 pandemic. Surveillance efforts rely on the availability of representative clinical specimens from ongoing testing activities. However, testing practices ha
Externí odkaz:
https://doaj.org/article/9d13640c04ad4305b9c14af4575892d0
Autor:
Luisa Santus, Maria Sopena-Rios, Raquel García-Pérez, Aaron E. Lin, Gordon C. Adams, Kayla G. Barnes, Katherine J. Siddle, Shirlee Wohl, Ferran Reverter, John L. Rinn, Richard S. Bennett, Lisa E. Hensley, Pardis C. Sabeti, Marta Melé
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-14 (2023)
Abstract Long non-coding RNAs (lncRNAs) are involved in numerous biological processes and are pivotal mediators of the immune response, yet little is known about their properties at the single-cell level. Here, we generate a multi-tissue bulk RNAseq
Externí odkaz:
https://doaj.org/article/5370a6f7e4c54340b26405e7cf365b14
Autor:
Shira Weingarten-Gabbay, Da-Yuan Chen, Siranush Sarkizova, Hannah B. Taylor, Matteo Gentili, Gabrielle M. Hernandez, Leah R. Pearlman, Matthew R. Bauer, Charles M. Rice, Karl R. Clauser, Nir Hacohen, Steven A. Carr, Jennifer G. Abelin, Mohsan Saeed, Pardis C. Sabeti
Publikováno v:
Cell Reports, Vol 43, Iss 1, Pp 113596- (2024)
Summary: Targeted synthetic vaccines have the potential to transform our response to viral outbreaks, yet the design of these vaccines requires a comprehensive knowledge of viral immunogens. Here, we report severe acute respiratory syndrome coronavir
Externí odkaz:
https://doaj.org/article/db8ea015b89d430fb372f8118aea4ea2
Autor:
Lao-Tzu Allan-Blitz, Palak Shah, Gordon Adams, John A. Branda, Jeffrey D. Klausner, Robert Goldstein, Pardis C. Sabeti, Jacob E. Lemieux
Publikováno v:
mSphere, Vol 8, Iss 5 (2023)
ABSTRACT Neisseria gonorrhoeae is one of the most common bacterial sexually transmitted infections. The emergence of antimicrobial-resistant N. gonorrhoeae is an urgent public health threat. Currently, the diagnosis of N. gonorrhoeae infection requir
Externí odkaz:
https://doaj.org/article/528fe29a4d654547a523bdad52e26cd3
Autor:
Idowu B. Olawoye, Paul E. Oluniyi, Judith U. Oguzie, Jessica N. Uwanibe, Tolulope A. Kayode, Testimony J. Olumade, Fehintola V. Ajogbasile, Edyth Parker, Philomena E. Eromon, Priscilla Abechi, Tope A. Sobajo, Chinedu A. Ugwu, Uwem E. George, Femi Ayoade, Kazeem Akano, Nicholas E. Oyejide, Iguosadolo Nosamiefan, Iyanuoluwa Fred-Akintunwa, Kemi Adedotun-Sulaiman, Farida B. Brimmo, Babatunde B. Adegboyega, Courage Philip, Richard A. Adeleke, Grace C. Chukwu, Muhammad I. Ahmed, Oludayo O. Ope-Ewe, Shobi G. Otitoola, Olusola A. Ogunsanya, Mudasiru F. Saibu, Ayotunde E. Sijuwola, Grace O. Ezekiel, Oluwagboadurami G. John, Julie O. Akin-John, Oluwasemilogo O. Akinlo, Olanrewaju O. Fayemi, Testimony O. Ipaye, Deborah C. Nwodo, Abolade E. Omoniyi, Iyobosa B. Omwanghe, Christabel A. Terkuma, Johnson Okolie, Olubukola Ayo-Ale, Odia Ikponmwosa, Ebo Benevolence, Grace O. Naregose, Akhilomen E. Patience, Osiemi Blessing, Airende Micheal, Agbukor Jacqueline, John O. Aiyepada, Paulson Ebhodaghe, Omiunu Racheal, Esumeh Rita, Giwa E. Rosemary, Ehikhametalor Solomon, Ekanem Anieno, Yerumoh Edna, Aire O. Chris, Adomeh I. Donatus, Ephraim Ogbaini-Emovon, Mirabeau Y. Tatfeng, Hannah E. Omunakwe, Mienye Bob-Manuel, Rahaman A. Ahmed, Chika K. Onwuamah, Joseph O. Shaibu, Azuka Okwuraiwe, Anthony E. Ataga, Andrew Bock-Oruma, Funmi Daramola, Ibrahim F. Yusuf, Akinwumi Fajola, Nsikak-Abasi Ntia, Julie J. Ekpo, Anietie E. Moses, Beatrice W. Moore-Igwe, Oluwatosin E. Fakayode, Monilade Akinola, Ibrahim M. Kida, Bamidele S. Oderinde, Zara W. Wudiri, Oluwapelumi O. Adeyemi, Olusola A. Akanbi, Anthony Ahumibe, Afolabi Akinpelu, Oyeronke Ayansola, Olajumoke Babatunde, Adesuyi A. Omoare, Chimaobi Chukwu, Nwando G. Mba, Ewean C. Omoruyi, Olasunkanmi Olisa, Olatunji K. Akande, Ifeanyi E. Nwafor, Matthew A. Ekeh, Erim Ndoma, Richard L. Ewah, Rosemary O. Duruihuoma, Augustine Abu, Elizabeth Odeh, Venatius Onyia, Chiedozie K. Ojide, Sylvanus Okoro, Daniel Igwe, Emeka O. Ogah, Kamran Khan, Nnennaya A. Ajayi, Collins N. Ugwu, Kingsley N. Ukwaja, Ngozi I. Ugwu, Chukwuyem Abejegah, Nelson Adedosu, Olufemi Ayodeji, Ahmed A. Liasu, Rafiu O. Isamotu, Galadima Gadzama, Brittany A. Petros, Katherine J. Siddle, Stephen F. Schaffner, George Akpede, Cyril Oshomah Erameh, Marycelin M. Baba, Femi Oladiji, Rosemary Audu, Nnaemeka Ndodo, Adeola Fowotade, Sylvanus Okogbenin, Peter O. Okokhere, Danny J. Park, Bronwyn L. Mcannis, Ifedayo M. Adetifa, Chikwe Ihekweazu, Babatunde L. Salako, Oyewale Tomori, Anise N. Happi, Onikepe A. Folarin, Kristian G. Andersen, Pardis C. Sabeti, Christian T. Happi
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-10 (2023)
Data on geographically restricted SARS-CoV-2 variants is lacking in some regions. In this nationwide effort including 18 public health labs, the authors used genomic epidemiology and travel data to understand the origin and spread of 2 variants of in
Externí odkaz:
https://doaj.org/article/aac72966fde2439a833d19f9a1131064
Autor:
Erica Normandin, Melissa Rudy, Nikolaos Barkas, Stephen F. Schaffner, Zoe Levine, Robert F. Padera, Mehrtash Babadi, Shibani S. Mukerji, Daniel J. Park, Bronwyn L. MacInnis, Katherine J. Siddle, Pardis C. Sabeti, Isaac H. Solomon
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-12 (2023)
Here, by high-resolution SARS-CoV-2 sequencing, genomic and transcriptomic analyses from tissue samples, Normandin et al. investigate viral dynamics in fatal cases of COVID-19, revealing persistent infection in distinct anatomical sites, including th
Externí odkaz:
https://doaj.org/article/f3271dabc2c74b9d8e1372480f2f4b46
Autor:
Jacob E. Lemieux, Weihua Huang, Nathan Hill, Tjasa Cerar, Lisa Freimark, Sergio Hernandez, Matteo Luban, Vera Maraspin, Petra Bogovič, Katarina Ogrinc, Eva Ruzič-Sabljič, Pascal Lapierre, Erica Lasek-Nesselquist, Navjot Singh, Radha Iyer, Dionysios Liveris, Kurt D. Reed, John M. Leong, John A. Branda, Allen C. Steere, Gary P. Wormser, Franc Strle, Pardis C. Sabeti, Ira Schwartz, Klemen Strle
Publikováno v:
PLoS Pathogens, Vol 19, Iss 8 (2023)
Lyme disease is the most common vector-borne disease in North America and Europe. The clinical manifestations of Lyme disease vary based on the genospecies of the infecting Borrelia burgdorferi spirochete, but the microbial genetic elements underlyin
Externí odkaz:
https://doaj.org/article/44c21f7ffd0942d9873167f12a2afdc2
Autor:
Ivan Specht, Kian Sani, Yolanda Botti-Lodovico, Michael Hughes, Kristin Heumann, Amy Bronson, John Marshall, Emily Baron, Eric Parrie, Olivia Glennon, Ben Fry, Andrés Colubri, Pardis C. Sabeti
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-7 (2022)
Abstract Amid COVID-19, many institutions deployed vast resources to test their members regularly for safe reopening. This self-focused approach, however, not only overlooks surrounding communities but also remains blind to community transmission tha
Externí odkaz:
https://doaj.org/article/4e5e9a85aee346bab2bb79b4121a7a1a