Zobrazeno 1 - 10
of 55
pro vyhledávání: '"Pardes Habib"'
Autor:
Amelie Heesch, Alexandru Florea, Jochen Maurer, Pardes Habib, Laura S. Werth, Thomas Hansen, Elmar Stickeler, Sabri E. M. Sahnoun, Felix M. Mottaghy, Agnieszka Morgenroth
Publikováno v:
Breast Cancer Research, Vol 26, Iss 1, Pp 1-11 (2024)
Abstract Introduction Overexpression of prostate-specific membrane antigen (PSMA) on the vasculature of triple-negative breast cancer (TNBC) presents a promising avenue for targeted endogenous radiotherapy with [177Lu]Lu-PSMA-I&T. This study aimed to
Externí odkaz:
https://doaj.org/article/6775a6f1a0f44615b328c65d69afcf81
Autor:
Fabian Edsen, Pardes Habib, Oliver Matz, Omid Nikoubashman, Martin Wiesmann, Michael Frick, Nikolaus Marx, Jörg B. Schulz, Arno Reich, João Pinho
Publikováno v:
Annals of Clinical and Translational Neurology, Vol 9, Iss 10, Pp 1668-1672 (2022)
Abstract Epicardial adipose tissue is involved in the pathophysiology of atrial fibrillation (AF). This study aimed to analyze its relevance as a stroke etiology marker. A retrospective study of acute ischemic stroke patients with large vessel occlus
Externí odkaz:
https://doaj.org/article/3a679902f71a4c89afa7a2a2ba8d33e9
Autor:
Michael A Margreiter, Monika Witzenberger, Yasmine Wasser, Elena Davydova, Robert Janowski, Jonas Metz, Pardes Habib, Sabri E.M. Sahnoun, Carina Sobisch, Benedetta Poma, Oscar Palomino-Hernandez, Mirko Wagner, Thomas Carell, N. Jon Shah, Jörg B. Schulz, Dierk Niessing, Aaron Voigt, Giulia Rossetti
Publikováno v:
Computational and Structural Biotechnology Journal, Vol 20, Iss , Pp 443-458 (2022)
Polyglutamine (polyQ) diseases are characterized by an expansion of cytosine-adenine-guanine (CAG) trinucleotide repeats encoding for an uninterrupted prolonged polyQ tract. We previously identified TRMT2A as a strong modifier of polyQ-induced toxici
Externí odkaz:
https://doaj.org/article/b64bb5ae313246c5aac74fe4b11f4b6c
Publikováno v:
STAR Protocols, Vol 3, Iss 3, Pp 101634- (2022)
Summary: Hypoxia plays a pivotal role in the pathogenesis of major causes of mortality such as cerebral ischemia. Here, we present a standardized protocol for the induction of global hypoxia and reoxygenation in Drosophila melanogaster, with details
Externí odkaz:
https://doaj.org/article/0f65c01b63494912b8a14d3082db5bea
Autor:
Eren Arik, Ole Heinisch, Michaela Bienert, Lara Gubeljak, Alexander Slowik, Arno Reich, Jörg B. Schulz, Thomas Wilhelm, Michael Huber, Pardes Habib
Publikováno v:
Frontiers in Cellular Neuroscience, Vol 16 (2022)
Recombinant human erythropoietin (rhEPO) has been shown to exert anti-apoptotic and anti-inflammatory effects after cerebral ischemia. Inflammatory cytokines interleukin-1β and -18 (IL-1β and IL-18) are crucial mediators of apoptosis and are matura
Externí odkaz:
https://doaj.org/article/edc93ba0d98845ee84c099f8ef29c8bd
Autor:
Anne K. Braczynski, Marc Sevenich, Ian Gering, Tatsiana Kupreichyk, Emil D. Agerschou, Yannick Kronimus, Pardes Habib, Matthias Stoldt, Dieter Willbold, Jörg B. Schulz, Jan-Philipp Bach, Björn H. Falkenburger, Wolfgang Hoyer
Publikováno v:
Biomolecules, Vol 12, Iss 3, p 469 (2022)
Parkinson’s disease (PD) is associated with motor and non-motor symptoms and characterized by aggregates of alpha-synuclein (αSyn). Naturally occurring antibodies (nAbs) are part of the innate immune system, produced without prior contact to their
Externí odkaz:
https://doaj.org/article/c8cede19861348caa055202bb9372ad7
α1-antitrypsin mitigates NLRP3-inflammasome activation in amyloid β1–42-stimulated murine astrocytes
Autor:
Taraneh Ebrahimi, Marcus Rust, Sarah Nele Kaiser, Alexander Slowik, Cordian Beyer, Andreas Rembert Koczulla, Jörg B. Schulz, Pardes Habib, Jan Philipp Bach
Publikováno v:
Journal of Neuroinflammation, Vol 15, Iss 1, Pp 1-15 (2018)
Abstract Background Neuroinflammation has an essential impact on the pathogenesis and progression of Alzheimer’s disease (AD). Mostly mediated by microglia and astrocytes, inflammatory processes lead to degeneration of neuronal cells. The NLRP3-inf
Externí odkaz:
https://doaj.org/article/d19d4b4fd72749d4a06e9595c819751b
Publikováno v:
Cells, Vol 10, Iss 11, p 2830 (2021)
The pathological accumulation of α-Synuclein (α-Syn) is the hallmark of neurodegenerative α-synucleinopathies, including Parkinsons’s disease (PD). In contrast to the mostly non-phosphorylated soluble α-Syn, aggregated α-Syn is usually phospho
Externí odkaz:
https://doaj.org/article/4167b442f4db4701b03eff41f93c238e
Autor:
Chinmaya Panda, Clara Voelz, Pardes Habib, Christian Mevissen, Thomas Pufe, Cordian Beyer, Sharad Gupta, Alexander Slowik
Publikováno v:
Cells, Vol 10, Iss 7, p 1652 (2021)
Intra-neuronal misfolding of monomeric tau protein to toxic β-sheet rich neurofibrillary tangles is a hallmark of Alzheimer’s disease (AD). Tau pathology correlates not only with progressive dementia but also with microglia-mediated inflammation i
Externí odkaz:
https://doaj.org/article/4a3ba6f8057f45cc971a38580d4cc394
Autor:
Fabian Edsen, Pardes Habib, Oliver Matz, Omid Nikoubashman, Martin Wiesmann, Michael Frick, Nikolaus Marx, Jörg B. Schulz, Arno Reich, João Pinho
Publikováno v:
Annals of Clinical and Translational Neurology. 9:1668-1672
Epicardial adipose tissue is involved in the pathophysiology of atrial fibrillation (AF). This study aimed to analyze its relevance as a stroke etiology marker. A retrospective study of acute ischemic stroke patients with large vessel occlusion was c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b860f4c3dd41155a9ca5e8037fb34f6b
https://doi.org/10.1002/acn3.51617
https://doi.org/10.1002/acn3.51617