Zobrazeno 1 - 10
of 97
pro vyhledávání: '"Parbo, P."'
Autor:
Kristian Juul-Madsen, Peter Parbo, Rola Ismail, Peter L. Ovesen, Vanessa Schmidt, Lasse S. Madsen, Jacob Thyrsted, Sarah Gierl, Mihaela Breum, Agnete Larsen, Morten N. Andersen, Marina Romero-Ramos, Christian K. Holm, Gregers R. Andersen, Huaying Zhao, Peter Schuck, Jens V. Nygaard, Duncan S. Sutherland, Simon F. Eskildsen, Thomas E. Willnow, David J. Brooks, Thomas Vorup-Jensen
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-20 (2024)
Abstract The peripheral immune system is important in neurodegenerative diseases, both in protecting and inflaming the brain, but the underlying mechanisms remain elusive. Alzheimer’s Disease is commonly preceded by a prodromal period. Here, we rep
Externí odkaz:
https://doaj.org/article/81c39ad41509420b82e48e637c1da445
Akademický článek
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Autor:
Lasse S. Madsen, Rune B. Nielsen, Peter Parbo, Rola Ismail, Irene K. Mikkelsen, Hanne Gottrup, Leif Østergaard, David J. Brooks, Simon F. Eskildsen
Publikováno v:
Aging Brain, Vol 2, Iss , Pp 100035- (2022)
Cardiovascular risk factors are associated with the development of Alzheimer’s disease (AD), and increasing evidence suggests that cerebral microvascular dysfunction plays a vital role in the disease progression. Using magnetic resonance imaging, w
Externí odkaz:
https://doaj.org/article/7c197089d395425ab1fc07797aaaeb63
Autor:
Pernille L. Kjeldsen, Peter Parbo, Kim V. Hansen, Joel F.A. Aanerud, Rola Ismail, Peter H. Nissen, Rikke B. Dalby, Malene F. Damholdt, Per Borghammer, David J. Brooks
Publikováno v:
Aging Brain, Vol 2, Iss , Pp 100048- (2022)
Introduction: The typical spatial pattern of amyloid-β (Aβ) in diagnosed Alzheimer’s disease (AD) is that of a symmetrical hemispheric distribution. However, Aβ may be asymmetrically distributed in early stages of AD. Aβ distribution on PET has
Externí odkaz:
https://doaj.org/article/d4f233cd10d145528054e34755010fb9
Autor:
Rola Ismail, Peter Parbo, Lasse Stensvig Madsen, Allan K. Hansen, Kim V. Hansen, Jeppe L. Schaldemose, Pernille L. Kjeldsen, Morten G. Stokholm, Hanne Gottrup, Simon F. Eskildsen, David J. Brooks
Publikováno v:
Journal of Neuroinflammation, Vol 17, Iss 1, Pp 1-11 (2020)
Abstract Background The aim of this longitudinal study was to assess with positron emission tomography (PET) the relationship between levels of inflammation and the loads of aggregated β-amyloid and tau at baseline and again after 2 years in prodrom
Externí odkaz:
https://doaj.org/article/d6cbb349346a47e69fbe4d108ae94551
Autor:
Peter Parbo, Lasse Stensvig Madsen, Rola Ismail, Henrik Zetterberg, Kaj Blennow, Simon F. Eskildsen, Thomas Vorup-Jensen, David J. Brooks
Publikováno v:
Alzheimer’s Research & Therapy, Vol 12, Iss 1, Pp 1-7 (2020)
Abstract Background Plasma and cerebrospinal fluid levels of neurofilament light (NfL), a marker of axonal degeneration, have previously been reported to be raised in patients with clinically diagnosed Alzheimer’s disease (AD). Activated microglia,
Externí odkaz:
https://doaj.org/article/e074fe041f254675a330d994a13e4f4b
Autor:
Madsen, Lasse S., Kjeldsen, Pernille L., Ismail, Rola, Parbo, Peter, Østergaard, Leif, Brooks, David J., Eskildsen, Simon F.
Publikováno v:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association; Jan2024, Vol. 20 Issue 1, p459-471, 13p
Akademický článek
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Autor:
Rune B. Nielsen, Peter Parbo, Rola Ismail, Rikke Dalby, Anna Tietze, Hans Brændgaard, Hanne Gottrup, David J. Brooks, Leif Østergaard, Simon F. Eskildsen
Publikováno v:
Alzheimer’s & Dementia: Diagnosis, Assessment & Disease Monitoring, Vol 12, Iss 1, Pp n/a-n/a (2020)
Abstract Introduction Cardiovascular disease increases the risk of developing Alzheimer's disease (AD), and growing evidence suggests an involvement of cerebrovascular pathology in AD. Capillary dysfunction, a condition in which capillary flow distur
Externí odkaz:
https://doaj.org/article/c8611cfcd4714bfc89312f75d42fd35a
Autor:
Peter Parbo, Rola Ismail, Michael Sommerauer, Morten G. Stokholm, Allan K. Hansen, Kim V. Hansen, Ali Amidi, Jeppe L. Schaldemose, Hanne Gottrup, Hans Brændgaard, Simon F. Eskildsen, Per Borghammer, Rainer Hinz, Joel Aanerud, David J. Brooks
Publikováno v:
Neurobiology of Disease, Vol 117, Iss , Pp 211-216 (2018)
Objective: Our aim was to assess with positron emission tomography (PET) the temporal and spatial inter-relationships between levels of cortical microglial activation and the aggregated amyloid-β and tau load in mild cognitive impairment (MCI) and e
Externí odkaz:
https://doaj.org/article/5538e535c0454476a035cf05a4b9006c