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of 2
pro vyhledávání: '"Parbir S. Grewal"'
Autor:
Michael E. Pyne, Kaspar Kevvai, Parbir S. Grewal, Lauren Narcross, Brian Choi, Leanne Bourgeois, John E. Dueber, Vincent J. J. Martin
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-10 (2020)
Plants synthesize more than 3000 tetrahydroisoquinoline (THIQ) alkaloids, but only a few of them have been produced by engineered microbes and titers are very low. Here, the authors increase (S)-reticuline titer to 4.6 g/L and repurpose the yeast Ehr
Externí odkaz:
https://doaj.org/article/1711736c3c694987b81eeec5d825890d
Publikováno v:
Nature chemical biology. 17(1)
Eukaryotic cells compartmentalize metabolic pathways in organelles to achieve optimal reaction conditions and avoid crosstalk with cytosolic factors. We found that cytosolic expression of norcoclaurine synthase (NCS), the enzyme that catalyzes the fi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::afb8846ea63dbd4dfaf1a09007fd9e27
https://pubmed.ncbi.nlm.nih.gov/33116303
https://pubmed.ncbi.nlm.nih.gov/33116303