Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Paraxial mesoderm formation"'
Autor:
Simon Moxon, Tatjana Sauka-Spengler, Eirini Maniou, Ruth M. Williams, Grant N. Wheeler, Gi Fay Mok, Leighton Folkes, Andrea Münsterberg, Alice M. Godden, Shannon A. Weldon, Victor Martinez-Heredia
Publikováno v:
Nature Communications
Nature Communications, Vol 12, Iss 1, Pp 1-15 (2021)
Nature Communications, Vol 12, Iss 1, Pp 1-15 (2021)
Somites arising from paraxial mesoderm are a hallmark of the segmented vertebrate body plan. They form sequentially during axis extension and generate musculoskeletal cell lineages. How paraxial mesoderm becomes regionalised along the axis and how th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::70ffc79d2dde5e8e685b445f90500ef8
https://doi.org/10.1038/s41467-021-21426-7
https://doi.org/10.1038/s41467-021-21426-7
Autor:
Andrea Münsterberg, Victor Martinez-Heredia, Eirini Maniou, Ruth M. Williams, Gi Fay Mok, Grant N. Wheeler, Shannon A. Weldon, Leighton Folkes, Simon Moxon, Alice M. Godden
SUMMARYThe development of multicellular organisms is exquisitely regulated through differential gene activity, which governs cell differentiation programs. However, many details of spatiotemporal control of gene regulation are still poorly understood
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a4f55ea3776eab04fb24652919e8e371
https://doi.org/10.1101/2020.01.20.912337
https://doi.org/10.1101/2020.01.20.912337
Autor:
Jared C. Talbot, Zachary T. Morrow, Kazuyuki Hoshijima, David Grunwald, Adrienne M. Maxwell, Sharon L. Amacher
Publikováno v:
Developmental Dynamics. 246:759-769
Background: T-box genes encode a large transcription factor family implicated in many aspects of development. We are focusing on two related zebrafish T-box genes, tbx6l and tbx16, that are expressed in highly overlapping patterns in embryonic paraxi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7c6e8ef34999d9494c01064bd7b0074f
https://doi.org/10.1002/dvdy.24547
https://doi.org/10.1002/dvdy.24547
Publikováno v:
Working with Stem Cells ISBN: 9783319305806
The rapid progress of research involving pluripotent stem cells in recent years provides an unprecedented opportunity to develop new and efficient cell replacement therapies for the treatment of degenerative diseases, such as muscular dystrophies. Ne
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0b1918d02807bd2ae39fc45e5b03f0a9
https://doi.org/10.1007/978-3-319-30582-0_16
https://doi.org/10.1007/978-3-319-30582-0_16
Autor:
Anna-Katerina Hadjantonakis, Anna Ferrer-Vaquer, Virginia E. Papaioannou, Daniel Concepcion, Sonja Nowotschin
Publikováno v:
Developmental Biology. 367:1-14
Paraxial mesoderm is the tissue which gives rise to the skeletal muscles and vertebral column of the body. A gene regulatory network operating in the formation of paraxial mesoderm has been described. This network hinges on three key factors, Wnt3a,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0d80ba658d2aa3090f8cc2885ffc87dc
https://doi.org/10.1016/j.ydbio.2012.04.012
https://doi.org/10.1016/j.ydbio.2012.04.012
Publikováno v:
genesis. 47:309-313
To study paraxial mesoderm formation in the mouse, transgenic lines that can be used to either selectively delete or express genes of interest in the paraxial mesoderm are required. We have generated a transgenic mouse line that expresses Cre recombi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::95c899b0d8f1df51ce6cb0e9799398e6
https://doi.org/10.1002/dvg.20503
https://doi.org/10.1002/dvg.20503
Autor:
Brian J. Cox, Janet Rossant, Rolf Kemler, Christian Wehrle, Makoto Mark Taketo, Heiko Lickert
Publikováno v:
Development 132, 2599-2609 (2005)
Differential gene regulation integrated in time and space drives developmental programs during embryogenesis. To understand how the program of gastrulation is regulated by Wnt/β-catenin signaling, we have used genome-wide expression profiling of con
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5acfd72ee4adb06522a264bbd56dbc5b
https://doi.org/10.1242/dev.01842
https://doi.org/10.1242/dev.01842
Publikováno v:
Mechanisms of Development. 119:251-256
Rib-vertebrae (rv) is an autosomal recessive mutation in mouse that affects somite formation, morphology, and patterning. Expression of Notch pathway components is affected in the paraxial mesoderm of rv mutant embryos, and rv and a null allele of th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::813c674a13bc365d38c6bcfd22f45ba7
https://doi.org/10.1016/s0925-4773(02)00394-5
https://doi.org/10.1016/s0925-4773(02)00394-5
Publikováno v:
Developmental Biology. 192:364-374
Thesec8gene, isolated in a gene trap screen in embryonic stem cells, is required for paraxial mesoderm formation in the mouse. Homozygoussec8mutant embryos initiate gastrulation but are unable to progress beyond the primitive streak stage and die sho
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4d24cc407060297092fae115a879d483
https://doi.org/10.1006/dbio.1997.8727
https://doi.org/10.1006/dbio.1997.8727
Autor:
Yasuko Onuma, Shuji Takahashi, Chang Yeol Yeo, Yoshikazu Haramoto, Makoto Asashima, Masakazu Fukuda, Yeon Jin Kim, Shoichi Ishiura
Publikováno v:
The International journal of developmental biology. 54(1)
The T-box gene VegT plays a crucial role during mesendoderm specification of the amphibian embryo. While the function of maternal VegT (mVegT) has been extensively investigated, little is known about the function and transcriptional regulation of zyg
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3b25315fabd1eea745c980d0098795c1
https://pubmed.ncbi.nlm.nih.gov/20013651
https://pubmed.ncbi.nlm.nih.gov/20013651