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Genetics of the thrombomodulin-endothelial cell protein C receptor system and the risk of early-onset ischemic stroke

Autor: Cole, J, Xu, H, Ryan, K, Jaworek, T, Dueker, N, McArdle, P, Gaynor, B, Cheng, Y, O'Connell, J, Bevan, S, Malik, R, Ahmed, N, Amouyel, P, Anjum, S, Bis, J, Crosslin, D, Danesh, J, Engelter, S, Fornage, M, Frossard, P, Gieger, C, Giese, A, Grond-Ginsbach, C, Ho, W, Holliday, E, Hopewell, J, Hussain, M, Iqbal, W, Jabeen, S, Jannes, J, Kamal, A, Kamatani, Y, Kanse, S, Kloss, M, Lathrop, M, Leys, D, Lindgren, A, Longstreth, W, Mahmood, K, Meisinger, C, Metso, T, Mosley, T, Müller-Nurasyid, M, Norrving, B, Parati, E, Peters, A, Pezzini, A, Quereshi, I, Rasheed, A, Rauf, A, Salam, T, Shen, J, Słowik, A, Stanne, T, Strauch, K, Tatlisumak, T, Thijs, V, Tiedt, S, Traylor, M, Waldenberger, M, Walters, M, Zhao, W, Boncoraglio, G, Debette, S, Jern, C, Levi, C, Markus, H, Meschia, J, Rolfs, A, Rothwell, P, Saleheen, D, Seshadri, S, Sharma, P, Sudlow, C, Worrall, B, Isgc, Metastroke Consortium Of The, Consortium, Wtccc-2, Stine, O, Kittner, S, Mitchell, B

Publikováno v: PLoS ONE
Sudlow, C, Cole, J W, Xu, H, Ryan, K, Jaworek, T, Dueker, N, McArdle, P, Gaynor, B, Cheng, Y-C, O’connell, J R, Bevan, S, Malik, R, Ahmed, N U, Amouyel, P, Anjum, S, Bis, J C, Crosslin, D S, Danesh, J, Mitchell, B D, Kittner, S J, Stine, C, Worrall, B B, Sharma, P, Seshadri, S, Engelter, S T, Fornage, M, Frossard, P, Gieger, C, Giese, A-K, Grond-ginsbach, C, Ho, W K, Holliday, E G, Rothwell, P M W, Hopewell, J C, Hussain, M, Warsi, I, Jabeen, S, Jannes, J, Kamal, A K, Kamatani, Y, Kanse, S, Kloss, M, Mark Lathrop, G, Leys, D, Lindgren, A, Longstreth, W T, Rothwell, P M, Saleheen, D, Jern, C, Levi, C, Hugh S, M, Meschia, J F, Rolfs, A, Walters, M, Zhao, W, Boncoraglio, G B, Debette, S, Waldenberger, M, Traylor, M, Tiedt, S, Thijs, V N, Mahmood, K, Meisinger, C, Metso, T M, Mosley, T H, Muller-Nurasyid, M, Norrving, B, Parati, E A, Peters, A, Pezzini, A, Quereshi, I, Rasheed, A, Rauf, A, Salam, T, Norman, J, Słowik, A, Stanne, T M, Strauch, K & Tatlisumak, T 2018, ' Genetics of the thrombomodulin-endothelial cell protein C receptor system and the risk of early-onset ischemic stroke ', PLoS ONE . https://doi.org/10.1371/journal.pone.0206554
PLoS ONE, Public Library of Science, 2018, 13 (11), pp.e0206554. ⟨10.1371/journal.pone.0206554⟩
PLoS ONE, Vol 13, Iss 11, p e0206554 (2018)

Background and purpose Polymorphisms in coagulation genes have been associated with early-onset ischemic stroke. Here we pursue an a priori hypothesis that genetic variation in the endothelial-based receptors of the thrombomodulin−protein C system

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::69035ca2aac3d7e85100ebf7f096b1d2
http://hdl.handle.net/10852/71347

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Akademický článek

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Akademický článek

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Genome-wide meta-analysis of cerebral white matter hyperintensities in patients with stroke

Autor: Traylor, M, Zhang, Cr, Adib Samii, P, Devan, Wj, Parsons, Oe, Lanfranconi, S, Gregory, S, Cloonan, L, Falcone, Gj, Radmanesh, F, Fitzpatrick, K, Kanakis, A, Barrick, Tr, Moynihan, B, Lewis, Cm, Boncoraglio, Gb, Lemmens, R, Thijs, V, Sudlow, C, Wardlaw, J, Rothwell, Pm, Meschia, Jf, Worrall, Bb, Levi, C, Bevan, S, Furie, Kl, Dichgans, M, Rosand, J, Markus, Hs, Rost, N, Smoller, S, Sorkin, J, Wang, X, Selim, M, Pikula, A, Wolf, P, Debette, S, Seshadri, S, de Bakker, P, Chasman, D, Rexrode, K, Chen, I, Rotter, J, Luke, M, Sale, M, Lee, Th, Chang, Kc, Elkind, M, Goldstein, L, James, Ml, Breteler, M, O'Donnell, C, Leys, D, Carty, C, Kidwell, C, Olesen, J, Sharma, P, Rich, S, Tatlisumak, T, Happola, O, Bijlenga, P, Soriano, C, Giralt, E, Roquer, J, Jimenez Conde, J, Cotlarcius, I, Hardy, J, Korostynski, M, Boncoraglio, G, Ballabio, E, Parati, E, Mateusz, A, Urbanik, A, Dziedzic, T, Jagiella, J, Gasowski, J, Wnuk, M, Olszanecki, R, Pera, J, Slowik, A, Juchniewicz, Kj, Nyquist, P, Cendes, I, Cabral, N, Franca, P, Goncalves, A, Keller, L, Crisby, M, Kostulas, K, Ahmadi, K, Opherk, C, Duering, M, Malik, R, Gonik, M, Staals, J, Melander, O, Burri, P, Sadr Nabavi, A, Romero, J, Biffi, A, Anderson, C, Falcone, G, Brouwers, B, Du, R, Kourkoulis, C, Battey, T, Lubitz, S, Mueller Myhsok, B, Meschia, J, Brott, T, Pare, G, Pichler, A, Enzinger, C, Schmidt, H, Schmidt, R, Seiler, S, Blanton, S, Yamada, Y, Bersano, A, Rundek, T, Sacco, R, Yvonne Chan, Yf, Gschwendtner, A, Deng, Z, Barr, T, Gwinn, K, Corriveau, R, Singleton, A, Waddy, S, Launer, L, Chen, C, Ke, Le, Lee, Wl, Tan, Ek, Olugbodi, A, Rothwell, P, Schilling, S, Mok, V, Lebedeva, E, Jern, C, Jood, K, Olsson, S, Kim, H, Lee, C, Kilarski, L, Markus, H, Peycke, J, Sheu, W, Chiou, Hy, Chern, J, Giraldo, E, Taqi, M, Jain, V, Lam, O, Howard, G, Woo, D, Kittner, S, Mitchell, B, Cole, J, O'Connell, J, Milewicz, D, Illoh, K, Worrall, B, Stine, C, Karaszewski, B, Werring, D, Sofat, R, Smalley, J, Lindgren, A, Hansen, B, Norrving, B, Smith, G, Martín, Jj, Klijn, K, Van't Hof, F, Algra, A, Macleod, M, Perry, R, Arnett, D, Pezzini, Alessandro, Padovani, Alessandro, Cramer, S, Fisher, M, Saleheen, D, Broderick, J, Kissela, B, Doney, A, Rannikmae, K, Silliman, S, Mcdonough, C, Walters, M, Pedersen, A, Nakagawa, K, Chang, C, Dobbins, M, Mcardle, P, Chang, Yc, Brown, R, Brown, D, Holliday, E, Kalaria, R, Maguire, J, Attia, J, Farrall, M, Giese, Ak, Fornage, M, Majersik, J, Cushman, M, Keene, K, Bennett, S, Tirschwell, D, Psaty, B, Reiner, A, Longstreth, W, Spence, D, Montaner, J, Fernandez Cadenas, I, Langefeld, C, Bushnell, C, Heitsch, L, Lee, Jm, Sheth, K.

Publikováno v: Neurology
Traylor, M, Zhang, C R, Adib-Samii, P, Devan, W J, Parsons, O E, Lanfranconi, S, Gregory, S, Cloonan, L, Falcone, G J, Radmanesh, F, Fitzpatrick, K, Kanakis, A, Barrick, T R, Moynihan, B, Lewis, C M, Boncoraglio, G B, Lemmens, R, Thijs, V, Sudlow, C, Wardlaw, J, Rothwell, P M, Meschia, J F, Worrall, B B, Levi, C, Bevan, S, Furie, K L, Dichgans, M, Rosand, J, Markus, H S & Rost, N 2016, ' Genome-wide meta-analysis of cerebral white matter hyperintensities in patients with stroke ', Neurology, vol. 86, no. 2, pp. 146-153 . https://doi.org/10.1212/WNL.0000000000002263
Traylor, M, Zhang, CR, Adib-samii, P, Devan, WJ, Parsons, OE, Lanfranconi, S, Gregory, S, Cloonan, L, Falcone, GJ, Radmanesh, F, Fitzpatrick, K, Kanakis, A, Barrick, T R, Moynihan, B, Lewis, CM, Boncoraglio, G, Lemmens, R, Thijs, V, Sudlow, C, Wardlaw, J, Rothwell, P M, Meschia, J F, Worrall, B B, Levi, C, Bevan, S, Furie, K L, Dichgans, M, Rosand, J & Markus, H S & Rost, NS 2016, ' Genome-wide meta-analysis of cerebral white matter hyperintensities in patients with stroke ', Neurology, vol. 86, pp. 146-153 . https://doi.org/10.1212/WNL.0000000000002263

Objective: For 3,670 stroke patients from the United Kingdom, United States, Australia, Belgium, and Italy, we performed a genome-wide meta-analysis of white matter hyperintensity volumes (WMHV) on data imputed to the 1000 Genomes reference dataset t

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::80d26018f3faecf89869b04ff1142e32
http://hdl.handle.net/11379/485218

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