Is lipoprotein(a) measurement important for cardiovascular risk stratification in children and adolescents?

Autor: Marco Giussani, Antonina Orlando, Elena Tassistro, Erminio Torresani, Giulia Lieti, Ilenia Patti, Claudia Colombrita, Ilaria Bulgarelli, Laura Antolini, Gianfranco Parati, Simonetta Genovesi

Publikováno v: Italian Journal of Pediatrics, Vol 50, Iss 1, Pp 1-9 (2024)

Abstract Background Elevated lipoprotein (Lp(a)) levels are associated with increased risk of atherosclerotic processes and cardiovascular events in adults. The amount of Lp(a) is mainly genetically determined. Therefore, it is important to identify

Externí odkaz: https://doaj.org/article/b5063d61237743a68975d11618c758cf

Correction: Epigenetic patterns, accelerated biological aging, and enhanced epigenetic drift detected 6 months following COVID‑19 infection: insights from a genome‑wide DNA methylation study

Autor: Luciano Calzari, Davide Fernando Dragani, Lucia Zanotti, Elvira Inglese, Romano Danesi, Rebecca Cavagnola, Alberto Brusati, Francesco Ranucci, Anna Maria Di Blasio, Luca Persani, Irene Campi, Sara De Martino, Antonella Farsetti, Veronica Barbi, Michela Gottardi Zamperla, Giulia Nicole Baldrighi, Carlo Gaetano, Gianfranco Parati, Davide Gentilini

Publikováno v: Clinical Epigenetics, Vol 16, Iss 1, Pp 1-2 (2024)

Externí odkaz: https://doaj.org/article/570306fdaada45f8afb88b99e6226de9

Single-Pill, Triple Antihypertensive Therapy in Rural Sub-Saharan Africa: Preliminary Experience

Autor: Clara Stroppa, Isabella Hunjan, Alice Umulisa, Benitha Irebe, Gianfranco Parati, Mario G. Bianchetti, Bienvenu Muvunyi, Evariste Ntaganda, Vincent Sinabubaraga, Dragana Radovanovic, Sebastiano A. G. Lava, Franco Muggli

Publikováno v: Cardiology and Therapy, Vol 13, Iss 2, Pp 431-442 (2024)

Abstract Introduction Worldwide, arterial hypertension is the foremost preventable and modifiable cardiovascular risk factor. In addition to lifestyle changes, recent international guidelines recommend single-pill, low-dose combinations as initial tr

Externí odkaz: https://doaj.org/article/ee8c37462bb3423f99827239beafd432

A matter of sex—persistent predictive value of MECKI score prognostic power in men and women with heart failure and reduced ejection fraction: a multicenter study

Autor: Giulia Grilli, Elisabetta Salvioni, Federica Moscucci, Alice Bonomi, Gianfranco Sinagra, Michele Schaeffer, Jeness Campodonico, Massimo Mapelli, Maddalena Rossi, Cosimo Carriere, Michele Emdin, Massimo Piepoli, Stefania Paolillo, Michele Senni, Claudio Passino, Anna Apostolo, Federica Re, Caterina Santolamazza, Damiano Magrì, Carlo M. Lombardi, Ugo Corrà, Rosa Raimondo, Antonio Cittadini, Annamaria Iorio, Andrea Salzano, Rocco Lagioia, Carlo Vignati, Roberto Badagliacca, Andrea Passantino, Pasquale Perrone Filardi, Michele Correale, Enrico Perna, Davide Girola, Marco Metra, Gaia Cattadori, Marco Guazzi, Giuseppe Limongelli, Gianfranco Parati, Fabiana De Martino, Maria Vittoria Matassini, Francesco Bandera, Maurizio Bussotti, Angela Beatrice Scardovi, Susanna Sciomer, Piergiuseppe Agostoni, MECKI Score Research Group, Armando Ferraretti, Cristina Gussago, Domenico Scrutinio, Donatella Bertipaglia, Elisa Battaia, Michele Moretti, Francesca Pietrucci, Geza Halasz, Bruno Capelli, Giovanna Gallo, Emiliano Fiori, Giovanni Marchese, Giuseppe Pacileo, Fabio Valente, Rossella Vastarella, Rita Gravino, Matilda Shkoza, Nikita Baracchini, Teresa Capovilla, Andrea Di Lenarda, Alberto Maria Marra, Roberta D’Assante, Giulia Crisci, Roberto Ricci, Luca Arcari, Sergio Caravita, Elena Viganò, Stefania Farina, Beatrice Pezzuto, Pietro Palermo, Mauro Contini, Paola Gugliandolo, Irene Mattavelli, Michele Della Rocca

Publikováno v: Frontiers in Cardiovascular Medicine, Vol 11 (2024)

BackgroundA sex-based evaluation of prognosis in heart failure (HF) is lacking.Methods and resultsWe analyzed the Metabolic Exercise test data combined with Cardiac and Kidney Indexes (MECKI) score registry, which includes HF with reduced ejection fr

Externí odkaz: https://doaj.org/article/dd800531adc14f9b826b5f5b2a843ce7

Host genetics and COVID-19 severity: increasing the accuracy of latest severity scores by Boolean quantum features

Autor: Gabriele Martelloni, Alessio Turchi, Chiara Fallerini, Andrea Degl’Innocenti, Margherita Baldassarri, Simona Olmi, Simone Furini, Alessandra Renieri, GEN-COVID Multicenter study, Francesca Mari, Sergio Daga, Ilaria Meloni, Mirella Bruttini, Susanna Croci, Mirjam Lista, Debora Maffeo, Elena Pasquinelli, Giulia Brunelli, Kristina Zguro, Viola Bianca Serio, Enrica Antolini, Simona Letizia Basso, Samantha Minetto, Giulia Rollo, Martina Rozza, Angela Rina, Rossella Tita, Maria Antonietta Mencarelli, Caterina Lo Rizzo, Anna Maria Pinto, Francesca Ariani, Francesca Montagnani, Mario Tumbarello, Ilaria Rancan, Massimiliano Fabbiani, Elena Bargagli, Laura Bergantini, Miriana d’Alessandro, Paolo Cameli, David Bennett, Federico Anedda, Simona Marcantonio, Sabino Scolletta, Federico Franchi, Maria Antonietta Mazzei, Susanna Guerrini, Edoardo Conticini, Luca Cantarini, Bruno Frediani, Danilo Tacconi, Chiara Spertilli Raffaelli, Arianna Emiliozzi, Marco Feri, Alice Donati, Raffaele Scala, Luca Guidelli, Genni Spargi, Marta Corridi, Cesira Nencioni, Leonardo Croci, Gian Piero Caldarelli, Davide Romani, Paolo Piacentini, Maria Bandini, Elena Desanctis, Silvia Cappelli, Anna Canaccini, Agnese Verzuri, Valentina Anemoli, Manola Pisani, Agostino Ognibene, Maria Lorubbio, Alessandro Pancrazzi, Massimo Vaghi, Antonella D’Arminio Monforte, Federica Gaia Miraglia, Mario U. Mondelli, Stefania Mantovani, Raffaele Bruno, Marco Vecchia, Marcello Maffezzoni, Enrico Martinelli, Massimo Girardis, Stefano Busani, Sophie Venturelli, Andrea Cossarizza, Andrea Antinori, Alessandra Vergori, Stefano Rusconi, Matteo Siano, Arianna Gabrieli, Agostino Riva, Daniela Francisci, Elisabetta Schiaroli, Carlo Pallotto, Saverio Giuseppe Parisi, Monica Basso, Sandro Panese, Stefano Baratti, Pier Giorgio Scotton, Francesca Andretta, Mario Giobbia, Renzo Scaggiante, Francesca Gatti, Francesco Castelli, Eugenia Quiros-Roldan, Melania Degli Antoni, Isabella Zanella, Matteo della Monica, Carmelo Piscopo, Mario Capasso, Roberta Russo, Immacolata Andolfo, Achille Iolascon, Giuseppe Fiorentino, Massimo Carella, Marco Castori, Giuseppe Merla, Gabriella Maria Squeo, Filippo Aucella, Pamela Raggi, Rita Perna, Matteo Bassetti, Antonio Di Biagio, Maurizio Sanguinetti, Luca Masucci, Alessandra Guarnaccia, Serafina Valente, Alex Di Florio, Marco Mandalà, Alessia Giorli, Lorenzo Salerni, Patrizia Zucchi, Pierpaolo Parravicini, Elisabetta Menatti, Tullio Trotta, Ferdinando Giannattasio, Gabriella Coiro, Fabio Lena, Gianluca Lacerenza, Cristina Mussini, Luisa Tavecchia, Lia Crotti, Gianfranco Parati, Roberto Menè, Maurizio Sanarico, Marco Gori, Francesco Raimondi, Alessandra Stella, Filippo Biscarini, Tiziana Bachetti, Maria Teresa La Rovere, Maurizio Bussotti, Serena Ludovisi, Katia Capitani, Simona Dei, Sabrina Ravaglia, Annarita Giliberti, Giulia Gori, Rosangela Artuso, Elena Andreucci, Angelica Pagliazzi, Erika Fiorentini, Antonio Perrella, Francesco Bianchi, Paola Bergomi, Emanuele Catena, Riccardo Colombo, Sauro Luchi, Giovanna Morelli, Paola Petrocelli, Sarah Iacopini, Sara Modica, Silvia Baroni, Giulia Micheli, Marco Falcone, Donato Urso, Giusy Tiseo, Tommaso Matucci, Davide Grassi, Claudio Ferri, Franco Marinangeli, Francesco Brancati, Antonella Vincenti, Valentina Borgo, Stefania Lombardi, Mirco Lenzi, Massimo Antonio Di Pietro, Francesca Vichi, Benedetta Romanin, Letizia Attala, Cecilia Costa, Andrea Gabbuti, Alessio Bellucci, Marta Colaneri, Patrizia Casprini, Cristoforo Pomara, Massimiliano Esposito, Roberto Leoncini, Michele Cirianni, Lucrezia Galasso, Marco Antonio Bellini, Chiara Gabbi, Nicola Picchiotti

Publikováno v: Frontiers in Genetics, Vol 15 (2024)

The impact of common and rare variants in COVID-19 host genetics has been widely studied. In particular, in Fallerini et al. (Human genetics, 2022, 141, 147–173), common and rare variants were used to define an interpretable machine learning model

Externí odkaz: https://doaj.org/article/2ccef210408b4a0bb20150b784f90208