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pro vyhledávání: '"Parathyroid chief cell"'
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Publikováno v:
Experimental and Clinical Transplantation. 20:854-862
Objectives: Tissue-specific immunogenicity can be characterized by the determination of human leukocyte antigens (HLA). Parathyroid hyperplasia tissue cells are presumed to have the ability to lose HLA class I expression profile during cultivation, w
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::895faf70760ccdf2a43a38b178d54445
https://doi.org/10.6002/ect.2018.0388
https://doi.org/10.6002/ect.2018.0388
Autor:
Sheridan M. Hoy
Publikováno v:
Drugs. 81:1593-1596
Upacicalcet (UPASITA®) is an intravenous calcimimetic agent being developed by Sanwa Kagaku Kenkyusho, under license from EA Pharma, for the treatment of secondary hyperparathyroidism (SHPT), a common and early complication of chronic kidney disease
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c3d4216793b439fc85240d43f0fcb108
https://doi.org/10.1007/s40265-021-01578-y
https://doi.org/10.1007/s40265-021-01578-y
Autor:
Chitresh Kumar, Lakshmy Ramakrishnan, P Chatterjee, Mehar Chand Sharma, M Tabin, M Boruah, Shipra Agarwal, S Kardam
Publikováno v:
Journal of Endocrinological Investigation. 45:337-346
Calcium sensing receptor (CaSR), on the surface of normal parathyroid cells, is essential for maintaining serum calcium levels. The normal pattern of CaSR immunostaining remains undefined and is presumptively circumferential. Given the physiological
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ff27e10665c28f6c5fa2764fcd95b144
https://doi.org/10.1007/s40618-021-01646-w
https://doi.org/10.1007/s40618-021-01646-w
Publikováno v:
Journal of Investigative Medicine. 69:785-788
Permanent hypoparathyroidism is an endocrine disease that is mostly associated with the disruption of the parathyroid glands during surgery. Allotransplantation is the most promising approach for treatment particularly for its cost-effective and exac
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e40afe40be2349f0e380afab4b309db0
https://doi.org/10.1136/jim-2020-001648
https://doi.org/10.1136/jim-2020-001648
The Role of Genetic Factors in Endocrine Tissues Development and Its Regulation In Vivo and In Vitro
Publikováno v:
Russian Journal of Genetics. 57:273-281
Endocrine cells can be fully functional after heterotopic transplantation into mammals, which makes them a promising tool for regenerative medicine. However, to date, cellular therapy for endocrine diseases is limited by the inability to efficiently
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::40474542cc872912ed88450ab4878610
https://doi.org/10.1134/s102279542103008x
https://doi.org/10.1134/s102279542103008x
Autor:
Rajesh V. Thakker, Radu Mihai
Publikováno v:
European Journal of Endocrinology
Background Permanent postsurgical hypoparathyroidism (POSH) is a major complication of anterior neck surgery in general and of thyroid surgery in particular. Depending on diagnostic criteria, up to 10% of patients undergoing bilateral thyroid surgery
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::33726ad6c81cade9347878f9a1d39b10
http://europepmc.org/articles/PMC8052514
http://europepmc.org/articles/PMC8052514
Publikováno v:
Biotechnology & Biotechnological Equipment, Vol 35, Iss 1, Pp 1207-1213 (2021)
With CRISPR/Cas9 gene editing technology, human umbilical cord mesenchymal stem cells (HUMSCs) were directionally induced to differentiate into parathyroid cells. The study provides the theoretical and experimental basis for the application of HUMSCs
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7ca0d09638fbfec0d660b75e65b600b6
https://doaj.org/article/1b785ee5f8cd472d8287e9a35aff371c
https://doaj.org/article/1b785ee5f8cd472d8287e9a35aff371c
Autor:
Hiroyuki Yamada, Masaaki Inaba, Yoshihiro Sugiura, Kazutsune Harada, Atsuto Inoue, Masanori Emoto, Tomoe Hirakawa, Mikiyasu Taguchi, Ikue Kobayashi, Noriyuki Hayashi, Yasuo Imanishi, Daichi Miyaoka, Aiko Fujioka
Publikováno v:
Journal of Bone and Mineral Metabolism. 39:396-403
Etelcalcetide (Parsabiv®, AMG 416/ONO-5163) is a novel allosteric modulator for the calcium-sensing receptor approved for hemodialysis patients with secondary hyperparathyroidism of uremia. Etelcalcetide reduced parathyroid hormone levels in hemodia
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9cdf37fc17e8b599df06d1a13824c6b3
https://doi.org/10.1007/s00774-020-01158-2
https://doi.org/10.1007/s00774-020-01158-2
Publikováno v:
American Journal of Physiology-Renal Physiology. 318:F639-F646
Little is known about changes in parathyroid cells when calcimimetics are withdrawn. We examined the response of parathyroid glands to cinacalcet (Cina) withdrawal in uremic Sprague-Dawley rats fed a high-phosphate diet to develop secondary hyperpara
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5787d2e473e7cfcf46667aa4df880dd6
https://doi.org/10.1152/ajprenal.00479.2019
https://doi.org/10.1152/ajprenal.00479.2019