Zobrazeno 1 - 10
of 26
pro vyhledávání: '"Parathyroid and Rare Bone Disorders"'
Autor:
Minyoung Park, Susana Tsao, Alden Smith, Deborah Murphy, Ami Knoefler, Mishaela R. Rubin, Sanchita Mourya, Loretta Gulley, Bob Sanders
Publikováno v:
Journal of the Endocrine Society
Background: Hypoparathyroidism (HP) is a rare disease that is characterized by insufficient levels of parathyroid hormone, resulting in hypocalcemia, hyperphosphatemia and hypercalciuria. Standard of care (SoC) consists of calcium and active vitamin
Autor:
Xiangbing David Wang, Niharika Yedla
Publikováno v:
Journal of the Endocrine Society
Introduction: The Fourth International Workshop in 2014 delineated guidelines for the diagnosis of NPHPT which include ruling out secondary causes of hyperparathyroidism, and recommended cutoffs for 25 vitamin D (25OHD) to be ≥20ng/mL. Keeping in m
Publikováno v:
Journal of the Endocrine Society
Background: Basal ganglia calcification (BGC) is a well-known complication of hypoparathyroidism. It is currently thought that increased serum phosphate or calcium x phosphate product may be major risk factors. However, the pathophysiology of BGC is
Autor:
Blandine Weiss, Patrick Loustau, Michael D. Culler, Deborah M. Mitchell, Soraya Allas, Dolly Sharma, Danette Astolfi, Kathleen L. Deering, Michael Mannstadt
Publikováno v:
Journal of the Endocrine Society
Objectives: Significant knowledge gaps exist regarding the clinical burden and practice patterns associated with chronic hypoparathyroidism (cHP). This study assessed the clinical burden and practice patterns in patients with cHP identified using sur
Publikováno v:
Journal of the Endocrine Society
Introduction: Hypophosphatasia (HPP) is an autosomal disease resulting from loss-of-function mutations in the ALPL gene encoding tissue-nonspecific alkaline phosphatase (TNSALP). The presentation and severity of the disease is highly variable ranging
Autor:
Joseph Theressa Nehu Parimi, Sowjanya Naha, Timur Gusov, Rajani Gundluru, F N U Marium, Hasan Syed, John Chen Liu
Publikováno v:
Journal of the Endocrine Society
Primary hyperparathyroidism (PHPT) is defined as excessive secretion of parathyroid hormone (PTH) originating from the parathyroid gland. The most common cause is a single parathyroid adenoma which is typically solid. Cystic parathyroid adenomas (CPA
Publikováno v:
Journal of the Endocrine Society
The dysregulation of systemic calcium homeostasis during malignancy is common in most patients with high-grade tumors. The associated comorbidity is known as cancer-induced hypercalcemia (CIH) which affects up to 30% of cases, in the absence of metas
Autor:
Mohammed Bashir, Noora Al-Thani, Mahmoud Zirie, Zaina Abdelhalim Alamer, Emad Naem, Tarik Elhadd, Wajiha Gul, Obada Salameh, Abdul B. Abou-Samra
Publikováno v:
Journal of the Endocrine Society
Introduction: Primary hyperparathyroidism (PHPT) is a common cause of hypercalcemia and mostly caused by benign solitary benign adenoma (80 to 85 %). Definite treatment is the surgical removal. The most commonly used diagnostic modalities are Sestami
Autor:
Eva Lau, Selma B. Souto, Ana Varela, Sandra Belo, Maria Manuel Silva, Fernando Mendonça, Daniela Salazar, João Sérgio Neves, Davide Carvalho, Cláudia Costa, Pedro M. Cabral, Marta Borges Canha, Sara Viana, Jorge Pedro, Patrícia Meira, Rita Lourenço, Maria João Ferreira, Paula Freitas, Vanessa Guerreiro
Publikováno v:
Journal of the Endocrine Society
Introduction: Bariatric surgery (BS) is an effective therapeutic approach for obese patients. It is associated with important gastrointestinal anatomic changes, predisposing these subjects to altered nutrient absorption that impact phosphocalcium met
Publikováno v:
Journal of the Endocrine Society
Background: Atypical parathyroid adenoma is a rare entity that share some pathology features of parathyroid carcinoma such as fibrosis. Little is known about the clinical behavior of atypical parathyroid adenomas. Pathologically, it is defined as a h