Zobrazeno 1 - 10
of 34
pro vyhledávání: '"Paraskevi Krashia"'
Autor:
Maria Luisa De Paolis, Ilaria Paoletti, Claudio Zaccone, Fioravante Capone, Marcello D’Amelio, Paraskevi Krashia
Publikováno v:
Translational Neurodegeneration, Vol 13, Iss 1, Pp 1-34 (2024)
Abstract The last decades have witnessed huge efforts devoted to deciphering the pathological mechanisms underlying Alzheimer’s Disease (AD) and to testing new drugs, with the recent FDA approval of two anti-amyloid monoclonal antibodies for AD tre
Externí odkaz:
https://doaj.org/article/1a3dd9392dfc4313b7daa2859c01f390
Autor:
Annabella Pignataro, Paraskevi Krashia, Margherita De Introna, Annalisa Nobili, Annamaria Sabetta, Francesca Stabile, Livia La Barbera, Sebastian Luca D’Addario, Rossella Ventura, Francesco Cecconi, Marcello D’Amelio, Martine Ammassari-Teule
Publikováno v:
Translational Psychiatry, Vol 13, Iss 1, Pp 1-12 (2023)
Abstract Female, but not male, mice with haploinsufficiency for the proautophagic Ambra1 gene show an autistic-like phenotype associated with hippocampal circuits dysfunctions which include loss of parvalbuminergic interneurons (PV-IN), decrease in t
Externí odkaz:
https://doaj.org/article/20d6a12b58d24bf89cfdf346e543b960
Autor:
Livia La Barbera, Annalisa Nobili, Emma Cauzzi, Ilaria Paoletti, Mauro Federici, Luana Saba, Cecilia Giacomet, Ramona Marino, Paraskevi Krashia, Marcello Melone, Flavio Keller, Nicola Biagio Mercuri, Maria Teresa Viscomi, Fiorenzo Conti, Marcello D’Amelio
Publikováno v:
Molecular Neurodegeneration, Vol 17, Iss 1, Pp 1-22 (2022)
Abstract Background Recent clinical and experimental studies have highlighted the involvement of Ventral Tegmental Area (VTA) dopamine (DA) neurons for the early pathogenesis of Alzheimer’s Disease (AD). We have previously described a progressive a
Externí odkaz:
https://doaj.org/article/2eec18c7824e4c398b158ca11f49f590
Publikováno v:
Neural Regeneration Research, Vol 20, Iss 5, Pp 1405-1406 (2025)
Externí odkaz:
https://doaj.org/article/4d7dd355aa7f4eae8a3a6485848b2167
Publikováno v:
Frontiers in Psychiatry, Vol 13 (2022)
Neuropsychiatric symptoms (NPS) occur in nearly all patients with Alzheimer's Disease (AD). Most frequently they appear since the mild cognitive impairment (MCI) stage preceding clinical AD, and have a prognostic importance. Unfortunately, these symp
Externí odkaz:
https://doaj.org/article/06b5d9be81374fa09dd7299b9437f406
Autor:
Michele Romoli, Paraskevi Krashia, Arjune Sen, Diego Franciotta, Matteo Gastaldi, Annalisa Nobili, Andrea Mancini, Elena Nardi Cesarini, Pasquale Nigro, Nicola Tambasco, Nicola B. Mercuri, Lucilla Parnetti, Massimiliano Di Filippo, Marcello D’Amelio, Sarosh R. Irani, Cinzia Costa, Paolo Calabresi
Publikováno v:
Annals of Clinical and Translational Neurology, Vol 6, Iss 11, Pp 2261-2269 (2019)
Abstract Objective Autoantibody‐mediated forms of encephalitis (AE) include neurological disorders characterized by subacute memory loss, movement disorders, and, often, frequent, focal epileptic seizures. Yet, the electrophysiological effects of t
Externí odkaz:
https://doaj.org/article/cf388d388dcb4407bd9a1ad7e5cf7a4f
Autor:
Paraskevi Krashia, Alberto Cordella, Annalisa Nobili, Livia La Barbera, Mauro Federici, Alessandro Leuti, Federica Campanelli, Giuseppina Natale, Gioia Marino, Valeria Calabrese, Francescangelo Vedele, Veronica Ghiglieri, Barbara Picconi, Giulia Di Lazzaro, Tommaso Schirinzi, Giulia Sancesario, Nicolas Casadei, Olaf Riess, Sergio Bernardini, Antonio Pisani, Paolo Calabresi, Maria Teresa Viscomi, Charles Nicholas Serhan, Valerio Chiurchiù, Marcello D’Amelio, Nicola Biagio Mercuri
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-19 (2019)
Resolvins are endogenous lipids with pro-resolving activity. Here the authors find that rats overexpressing human α-synuclein show defects in dopamine signalling before dopamine cell loss, and that this is associated with low Resolvin D1 levels and
Externí odkaz:
https://doaj.org/article/4400ee42af354c6ca10e2b68760be226
Autor:
Alberto Cordella, Paraskevi Krashia, Annalisa Nobili, Annabella Pignataro, Livia La Barbera, Maria Teresa Viscomi, Alessandro Valzania, Flavio Keller, Martine Ammassari-Teule, Nicola Biagio Mercuri, Nicola Berretta, Marcello D'Amelio
Publikováno v:
Neurobiology of Disease, Vol 116, Iss , Pp 142-154 (2018)
The functional loop involving the ventral tegmental area (VTA), dorsal hippocampus and nucleus accumbens (NAc) plays a pivotal role in the formation of spatial memory and persistent memory traces. In particular, the dopaminergic innervation from the
Externí odkaz:
https://doaj.org/article/78ab95f2ced6435c8f675269d247e8a4
Autor:
Annalisa Nobili, Emanuele Claudio Latagliata, Maria Teresa Viscomi, Virve Cavallucci, Debora Cutuli, Giacomo Giacovazzo, Paraskevi Krashia, Francesca Romana Rizzo, Ramona Marino, Mauro Federici, Paola De Bartolo, Daniela Aversa, Maria Concetta Dell’Acqua, Alberto Cordella, Marco Sancandi, Flavio Keller, Laura Petrosini, Stefano Puglisi-Allegra, Nicola Biagio Mercuri, Roberto Coccurello, Nicola Berretta, Marcello D’Amelio
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-14 (2017)
Dopaminergic dysfunction occurs in Alzheimer’s disease (AD). The authors show that in a mouse model of AD, loss of dopaminergic neurons in the ventral tegmental area, but not the substantia nigra, occurs at early pre-plaque stages, and may contribu
Externí odkaz:
https://doaj.org/article/0bfe3928a258483cb4eba1b96c8e6f16
Publikováno v:
Frontiers in Molecular Neuroscience, Vol 12 (2019)
Externí odkaz:
https://doaj.org/article/e3be52f49047479f9aaca8c1ce809a05