Zobrazeno 1 - 10
of 1 495
pro vyhledávání: '"Parasitophorous vacuole"'
Autor:
Zhi-Wei Zhang, Meng Wang, Li-Xiu Sun, Hany M. Elsheikha, Cheng-Lin Lei, Jin-Lei Wang, Bao-Quan Fu, Jian-Xun Luo, Xing-Quan Zhu, Ting-Ting Li
Publikováno v:
Parasites & Vectors, Vol 17, Iss 1, Pp 1-16 (2024)
Abstract Background To successfully replicate within the host cell, Toxoplasma gondii employs several mechanisms to overcome the host cell defenses and mitigate the harmful effects of the free radicals resulting from its own metabolic processes using
Externí odkaz:
https://doaj.org/article/d5526581245047be8aa269604713f5e4
Autor:
Barbara Clough, Daniel Fisch, Todd H. Mize, Vesela Encheva, Ambrosius Snijders, Eva-Maria Frickel
Publikováno v:
mSphere, Vol 8, Iss 6 (2023)
ABSTRACTInfection with the parasite Toxoplasma gondii leads to production of interferon gamma (IFNγ) that stimulates cells to upregulate defense proteins targeting the parasite for cell intrinsic elimination or growth restriction. Various host defen
Externí odkaz:
https://doaj.org/article/895407d7e0a14877a13c4bbd2aa74765
Publikováno v:
mSphere, Vol 8, Iss 4 (2023)
ABSTRACT Toxoplasma gondii is an obligate, intracellular parasite. Infection of a cell produces a unique niche for the parasite named the parasitophorous vacuole (PV) initially composed of host plasma membrane invaginated during invasion. The PV and
Externí odkaz:
https://doaj.org/article/76db4ae80b0b4c5097d89e961faf15b8
Autor:
Emi Hashizaki, Miwa Sasai, Daisuke Okuzaki, Tsubasa Nishi, Takashi Kobayashi, Shiroh Iwanaga, Masahiro Yamamoto
Publikováno v:
mBio, Vol 14, Iss 1 (2023)
ABSTRACT Toxoplasma gondii secretes various virulence effector molecules into host cells to disrupt host interferon-γ (IFN-γ)-dependent immunity. Among these effectors, ROP18 directly phosphorylates and inactivates IFN-inducible GTPases, such as im
Externí odkaz:
https://doaj.org/article/8cce4e57ccc947a185c4c4f86535081e
Akademický článek
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Publikováno v:
Parasites & Vectors, Vol 14, Iss 1, Pp 1-12 (2021)
Abstract Background Neospora caninum is an obligate intracellular parasite that invades host cells and replicates within the parasitophorous vacuole (PV), which resists fusion with host cell lysosomal compartments. To modify the PV, the parasite secr
Externí odkaz:
https://doaj.org/article/f8c0ba263b35491695bb38ada9af6589
Autor:
Minmin Wu, Ran An, Nan Zhou, Ying Chen, Haijian Cai, Qi Yan, Ru Wang, Qingli Luo, Li Yu, Lijian Chen, Jian Du
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Interferon-γ (IFN-γ)-activated macrophages restrain the replication of intracellular parasites and disrupt the integrity of vacuolar pathogens. The growth of the less virulent type II strain of Toxoplasma gondii (such as ME49) was strongly inhibite
Externí odkaz:
https://doaj.org/article/736076b845f34abfb1fe601e11da07e9
Autor:
Gregory L. Blatch
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 10 (2022)
Plasmodium falciparum is a unicellular protozoan parasite and causative agent of the most severe form of malaria in humans. The malaria parasite has had to develop sophisticated mechanisms to preserve its proteome under the changing stressful conditi
Externí odkaz:
https://doaj.org/article/224e618f302f490f900d4bfadd32152f
Autor:
George Ghartey-Kwansah, Frank Adu-Nti, Benjamin Aboagye, Amandus Ankobil, Edward Eyipe Essuman, Yeboah Kwaku Opoku, Samuel Abokyi, Emmanuel Kwasi Abu, Johnson Nyarko Boampong
Publikováno v:
Cell & Bioscience, Vol 10, Iss 1, Pp 1-11 (2020)
Abstract Background Autophagy has a crucial role in the defense against parasites. The interplay existing between host autophagy and parasites has varied outcomes due to the kind of host cell and microorganism. The presence of autophagic compartments
Externí odkaz:
https://doaj.org/article/3048ca1f8c4b46b8b5ec0a5a7622c777
Autor:
Xin Gao, Jigang Yin, Dongqiang Wang, Xiaohui Li, Ying Zhang, Chenchen Wang, Yuanyuan Zhang, Guan Zhu
Publikováno v:
Frontiers in Veterinary Science, Vol 8 (2021)
Apicomplexan parasites possess several unique secretory organelles, including rhoptries, micronemes, and dense granules, which play critical roles in the invasion of host cells. The molecular content of these organelles and their biological roles hav
Externí odkaz:
https://doaj.org/article/325ec3063131498381b532285fb20b61