Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Paras Gaur"'
Autor:
Gabriel Fenteany, Gaurav Sharma, Paras Gaur, Attila Borics, Edit Wéber, Ernő Kiss, Lajos Haracska
Publikováno v:
iScience, Vol 25, Iss 4, Pp 104053- (2022)
Summary: Ubiquitination of proliferating cell nuclear antigen (PCNA) triggers pathways of DNA damage tolerance, including mutagenic translesion DNA synthesis, and comprises a cascade of reactions involving the E1 ubiquitin-activating enzyme Uba1, the
Externí odkaz:
https://doaj.org/article/b4abc35bfc74403c82c1a411e01815c4
Publikováno v:
BMC Molecular and Cell Biology, Vol 21, Iss 1, Pp 1-16 (2020)
Abstract Background Ubiquitination and ubiquitin-like protein post-translational modifications play an enormous number of roles in cellular processes. These modifications are constituted of multistep reaction cascades. Readily implementable and robus
Externí odkaz:
https://doaj.org/article/73aebcb242d04449b6eda0ee75c35490
Publikováno v:
International Journal of Molecular Sciences; Volume 24; Issue 12; Pages: 10274
As many as 700,000 unique sequences in the human genome are predicted to fold into G-quadruplexes (G4s), non-canonical structures formed by Hoogsteen guanine–guanine pairing within G-rich nucleic acids. G4s play both physiological and pathological
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=multidiscipl::c91144800b0f071debd6c9cdb1097763
Publikováno v:
bioRxiv
As many as 700,000 unique sequences in the human genome are predicted to fold into G-quadruplexes (G4s), non-canonical structures formed by Hoogsteen guanine-guanine pairing within G-rich nucleic acids. G4s play both physiological and pathological ro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::096f27d60616a829c6da1081a2c3984b
https://europepmc.org/articles/PMC10197523/
https://europepmc.org/articles/PMC10197523/
Publikováno v:
RSC Advances. 11:8264-8276
The green tea polyphenol (−)-epigallocatechin-3-gallate (EGCG) and some of its analogs potently inhibit the ubiquitin-activating enzyme Uba1. In an effort to understand the possible molecular basis of inhibitory activity of EGCG, we conducted a mol
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e1832613eb32d11950bfb96e29724c5a
https://doi.org/10.1039/d0ra09847g
https://doi.org/10.1039/d0ra09847g
Publikováno v:
RSC advances. 11(14)
The green tea polyphenol (-)-epigallocatechin-3-gallate (EGCG) and some of its analogs potently inhibit the ubiquitin-activating enzyme Uba1. In an effort to understand the possible molecular basis of inhibitory activity of EGCG, we conducted a molec
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::55495ed0a7273b4945607d58a626bef8
https://pubmed.ncbi.nlm.nih.gov/35423322
https://pubmed.ncbi.nlm.nih.gov/35423322
Publikováno v:
BMC Molecular and Cell Biology, Vol 21, Iss 1, Pp 1-16 (2020)
BMC Molecular and Cell Biology
BMC Molecular and Cell Biology
Background Ubiquitination and ubiquitin-like protein post-translational modifications play an enormous number of roles in cellular processes. These modifications are constituted of multistep reaction cascades. Readily implementable and robust methods
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b55f6ec8a17e4c9d53090e1305b2940d
https://doi.org/10.1186/s12860-020-00262-5
https://doi.org/10.1186/s12860-020-00262-5
Autor:
Paras Gaur
Publikováno v:
International Journal for Research in Applied Science and Engineering Technology. :1226-1231
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7afecef0fc3d3e003821c1c30c16a5c2
https://doi.org/10.22214/ijraset.2017.10177
https://doi.org/10.22214/ijraset.2017.10177
Autor:
Paras Gaur, Gabriel Fenteany, László G. Puskás, Lili Hegedűs, Edit Wéber, Ernő Kiss, Tamás A. Martinek, Lajos Haracska, László Hackler, Kata Dudás
Publikováno v:
Scientific Reports
Scientific Reports, Vol 9, Iss 1, Pp 1-16 (2019)
Scientific Reports, Vol 9, Iss 1, Pp 1-16 (2019)
We developed and implemented a reconstituted system to screen for modulators of the ubiquitination of proliferating cell nuclear antigen, a process that activates pathways of DNA damage tolerance and drug resistance. We identified the primary putativ
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::76b7bae5998ebd76d220b5330693ebaf
https://doi.org/10.1038/s41598-019-48888-6
https://doi.org/10.1038/s41598-019-48888-6