Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Paranjay, Parikh"'
Autor:
Monica Bubenik, Pavel Mader, Philippe Mochirian, Fréderic Vallée, Jillian Clark, Jean-François Truchon, Alexander L. Perryman, Victor Pau, Igor Kurinov, Karl E. Zahn, Marie-Eve Leclaire, Robert Papp, Marie-Claude Mathieu, Martine Hamel, Nicole M. Duffy, Claude Godbout, Matias Casas-Selves, Jean-Pierre Falgueyret, Prasamit S. Baruah, Olivier Nicolas, Rino Stocco, Hugo Poirier, Giovanni Martino, Alexanne Bonneau Fortin, Anne Roulston, Amandine Chefson, Stéphane Dorich, Miguel St-Onge, Purvish Patel, Charles Pellerin, Stéphane Ciblat, Thomas Pinter, Francis Barabé, Majida El Bakkouri, Paranjay Parikh, Christian Gervais, Agnel Sfeir, Yael Mamane, Stephen J. Morris, W. Cameron Black, Frank Sicheri, Michel Gallant
Publikováno v:
Journal of Medicinal Chemistry. 65:13198-13215
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::947c93bf7b6803db8ed4beb935e92af5
https://doi.org/10.1021/acs.jmedchem.2c00998
https://doi.org/10.1021/acs.jmedchem.2c00998
Autor:
Monica, Bubenik, Pavel, Mader, Philippe, Mochirian, Fréderic, Vallée, Jillian, Clark, Jean-François, Truchon, Alexander L, Perryman, Victor, Pau, Igor, Kurinov, Karl E, Zahn, Marie-Eve, Leclaire, Robert, Papp, Marie-Claude, Mathieu, Martine, Hamel, Nicole M, Duffy, Claude, Godbout, Matias, Casas-Selves, Jean-Pierre, Falgueyret, Prasamit S, Baruah, Olivier, Nicolas, Rino, Stocco, Hugo, Poirier, Giovanni, Martino, Alexanne Bonneau, Fortin, Anne, Roulston, Amandine, Chefson, Stéphane, Dorich, Miguel, St-Onge, Purvish, Patel, Charles, Pellerin, Stéphane, Ciblat, Thomas, Pinter, Francis, Barabé, Majida, El Bakkouri, Paranjay, Parikh, Christian, Gervais, Agnel, Sfeir, Yael, Mamane, Stephen J, Morris, W Cameron, Black, Frank, Sicheri, Michel, Gallant
Publikováno v:
Journal of medicinal chemistry. 65(19)
DNA polymerase theta (Polθ) is an attractive synthetic lethal target for drug discovery, predicted to be efficacious against breast and ovarian cancers harboring BRCA-mutant alleles. Here, we describe our hit-to-lead efforts in search of a selective
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::531f44b082fb5f00fe6c2f82d97a48bc
https://pubmed.ncbi.nlm.nih.gov/36126059
https://pubmed.ncbi.nlm.nih.gov/36126059
Autor:
Mrugesh J. Patel, Kaushal P. Patel, Neeraj Jain, Paranjay Parikh, Alex Chauhan, Nilesh Pandey, Jignesh B. Timaniya
Publikováno v:
RSC Advances. 11:27627-27644
A series of novel pyrazoline scaffolds from coumarin–carbazole chalcones were synthesized. We explored various acetyl, amide, and phenyl substituents at the N-1 position of the pyrazoline core. The synthesized compounds were characterized by FTIR,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::31407c139fc522132ebc42d6417fe5a1
https://doi.org/10.1039/d1ra03970a
https://doi.org/10.1039/d1ra03970a
Publikováno v:
Medicinal Chemistry Research. 29:538-548
In the current study, a novel combinatorial library of substituted 1,2,4-oxadiazoles bearing pyridine and thiazole have been synthesized via the condensation reaction of amidoxime and carboxylic acids and its derivatives in two way. The titled compou
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ba70bc178225e77a440780833ce408ef
https://doi.org/10.1007/s00044-020-02505-8
https://doi.org/10.1007/s00044-020-02505-8
Publikováno v:
OncoTargets and therapy. 15
Vishal Unadkat,1,2 Shishir Rohit,1 Paranjay Parikh,3 Kaushal Patel,3 Vinod Sanna,4 Sanjay Singh2,5 1Kashiv Biosciences Pvt Ltd, Ahmedabad, 382210, Gujarat, India; 2Division of Biological & Life Sciences (Formerly Institute of Life Sciences), School o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eace9393c88ba09040cb04dfb801d23a
https://pubmed.ncbi.nlm.nih.gov/35535170
https://pubmed.ncbi.nlm.nih.gov/35535170
Publikováno v:
Bioorganic chemistry. 114
A molecular dynamics-based sampling of epidermal growth factor receptor tyrosine kinase (EGFR-TK) was carried out to search for energetically more stable protein, which was then used for molecular docking of a series of 1,2,4-oxadiazole derivatives p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::25b7da1cd5e8bc9c264a4a17b715054a
https://pubmed.ncbi.nlm.nih.gov/34768203
https://pubmed.ncbi.nlm.nih.gov/34768203
Publikováno v:
Journal of Molecular Structure. 1249:131605
We have described solvent-free preparation of new pyrano[2,3-c]-pyrazole-5-carbonitriles (1-10) from the reaction of 1,3-diketo ester, aryl hydrazine, aromatic aldehyde, and malononitrile catalyzed by Zinc triflate (which was recycled and reused up t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e51d17fa4a0f3db9383793779c58b7e3
https://doi.org/10.1016/j.molstruc.2021.131605
https://doi.org/10.1016/j.molstruc.2021.131605
Publikováno v:
Bioorganic Chemistry. 117:105459
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::04f153efc6c977ca15ab4c667b968f59
https://doi.org/10.1016/j.bioorg.2021.105459
https://doi.org/10.1016/j.bioorg.2021.105459
Autor:
Unadkat, Vishal (AUTHOR), Rohit, Shishir (AUTHOR), Parikh, Paranjay (AUTHOR), Patel, Kaushal (AUTHOR), Sanna, Vinod (AUTHOR), Singh, Sanjay (AUTHOR)
Publikováno v:
OncoTargets & Therapy. May2022, Vol. 15, p479-495. 17p.
Publikováno v:
ARKIVOC: Online Journal of Organic Chemistry. 2020, Vol. 2020, p155-167. 66p.