Zobrazeno 1 - 10
of 140
pro vyhledávání: '"Paranjapye A"'
Autor:
Shih-Hsing Leir, Svyatoslav Tkachenko, Alekh Paranjapye, Frederick Meckler, Arnaud J. Van Wettere, Jenny L. Kerschner, Elizabeth Kuznetsov, Makayla Schacht, Pulak Gillurkar, Misha Regouski, Iuri Viotti Perisse, Cheyenne M. Marriott, Ying Liu, Ian Bunderson, Kenneth L. White, Irina A. Polejaeva, Ann Harris
Publikováno v:
Molecular Medicine, Vol 30, Iss 1, Pp 1-29 (2024)
Abstract Background Pancreatic fibrosis is an early diagnostic feature of the common inherited disorder cystic fibrosis (CF). Many people with CF (pwCF) are pancreatic insufficient from birth and the replacement of acinar tissue with cystic lesions a
Externí odkaz:
https://doaj.org/article/3d9ef7d36912408cb3c56c41ca33552c
Autor:
Sriram Vaidyanathan, Jenny L. Kerschner, Alekh Paranjapye, Vrishti Sinha, Brian Lin, Tracy A. Bedrosian, Adrian J. Thrasher, Giandomenico Turchiano, Ann Harris, Matthew H. Porteus
Publikováno v:
Molecular Therapy: Nucleic Acids, Vol 35, Iss 1, Pp 102134- (2024)
A “universal strategy” replacing the full-length CFTR cDNA may treat >99% of people with cystic fibrosis (pwCF), regardless of their specific mutations. Cas9-based gene editing was used to insert the CFTR cDNA and a truncated CD19 (tCD19) enrichm
Externí odkaz:
https://doaj.org/article/b980cfbabc854f999ab24fb41f1df1a5
Autor:
Vaidyanathan, Sriram, Kerschner, Jenny L., Paranjapye, Alekh, Sinha, Vrishti, Lin, Brian, Bedrosian, Tracy A., Thrasher, Adrian J., Turchiano, Giandomenico, Harris, Ann, Porteus, Matthew H.
Publikováno v:
In Molecular Therapy - Nucleic Acids 12 March 2024 35(1)
Autor:
Arnaud J. Van Wettere, Shih‐Hsing Leir, Calvin U. Cotton, Misha Regouski, Iuri Viotti Perisse, Jenny L. Kerschner, Alekh Paranjapye, Zhiqiang Fan, Ying Liu, Makayla Schacht, Kenneth L. White, Irina A. Polejaeva, Ann Harris
Publikováno v:
FASEB BioAdvances, Vol 5, Iss 1, Pp 13-26 (2023)
Abstract Highly effective modulator therapies for cystic fibrosis (CF) make it a treatable condition for many people. However, although CF respiratory illness occurs after birth, other organ systems particularly in the digestive tract are damaged bef
Externí odkaz:
https://doaj.org/article/43c1be17a98f465c84755dd90b13f12b
Akademický článek
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Publikováno v:
Physiological Reports, Vol 11, Iss 11, Pp n/a-n/a (2023)
Abstract The airway epithelial cell line, 16HBE14o−, is an important cell model for studying airway disease. 16HBE14o− cells were originally generated from primary human bronchial epithelial cells by SV40‐mediated immortalization, a process tha
Externí odkaz:
https://doaj.org/article/f3b80707068b4937ab72b9f4a67a4357
Akademický článek
Tento výsledek nelze pro nepřihlášené uživatele zobrazit.
K zobrazení výsledku je třeba se přihlásit.
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Autor:
Kerschner, Jenny L.1 (AUTHOR), Paranjapye, Alekh1 (AUTHOR), Harris, Ann1 (AUTHOR) ann.harris@case.edu
Publikováno v:
Physiological Reports. Jun2023, Vol. 11 Issue 11, p1-12. 12p.
Publikováno v:
In Journal of Biological Chemistry August 2021 297(2)
Publikováno v:
European Journal of Cell Biology, Vol 101, Iss 3, Pp 151231- (2022)
The evolutionary relationship of cells within tissues having a similar function but located in different anatomical sites is of considerable biological interest. The development of single-cell RNA sequencing (scRNA-seq) protocols has greatly enhanced
Externí odkaz:
https://doaj.org/article/a31e211b13a24795b9063efe7a9fb326