Zobrazeno 1 - 10
of 22
pro vyhledávání: '"Paraish S. Misra"'
Autor:
Daniel J. Han, Rukhsana Aslam, Paraish S. Misra, Felix Chiu, Tanvi Ojha, Apu Chowdhury, Carmen K. Chan, Hoon-Ki Sung, Darren A. Yuen, Cynthia T. Luk
Publikováno v:
Molecular Metabolism, Vol 66, Iss , Pp 101594- (2022)
Objective: Adipose tissue is a very dynamic metabolic organ that plays an essential role in regulating whole-body glucose homeostasis. Dysfunctional adipose tissue hypertrophy with obesity is associated with fibrosis and type 2 diabetes. Yes-associat
Externí odkaz:
https://doaj.org/article/0cd4e995ce7b4cab97303ebcb9db4249
Autor:
Xiaolin He, Monica F. Tolosa, Tianzhou Zhang, Santosh Kumar Goru, Luisa Ulloa Severino, Paraish S. Misra, Caitríona M. McEvoy, Lauren Caldwell, Stephen G. Szeto, Feng Gao, Xiaolan Chen, Cassandra Atin, Victoria Ki, Noah Vukosa, Catherine Hu, Johnny Zhang, Christopher Yip, Adriana Krizova, Jeffrey L. Wrana, Darren A. Yuen
Publikováno v:
JCI Insight, Vol 7, Iss 4 (2022)
Fibrotic diseases account for nearly half of all deaths in the developed world. Despite its importance, the pathogenesis of fibrosis remains poorly understood. Recently, the two mechanosensitive transcription cofactors YAP and TAZ have emerged as imp
Externí odkaz:
https://doaj.org/article/4fe66df753c24722aff314855974d52f
Publikováno v:
BMC Nephrology, Vol 21, Iss 1, Pp 1-12 (2020)
Abstract Background While histopathologic changes correlate with functional impairment in cross-sectional studies of diabetic nephropathy (DN), whether these findings predict future rate of kidney function loss remains uncertain. We thus sought to ex
Externí odkaz:
https://doaj.org/article/22a320e0f7bf4ba69d65cf1c22a475e2
Publikováno v:
Canadian Journal of Kidney Health and Disease, Vol 6 (2019)
Background: Acute kidney injury (AKI) is a complex and heterogeneous clinical syndrome with limited effective treatment options. Therefore, a coherent research structure considering AKI pathophysiology, treatment, translation, and implementation is c
Externí odkaz:
https://doaj.org/article/7dd94ca58796445d8c14f87f1794c40c
Autor:
Tianzhou Zhang, Xiaolin He, Lauren Caldwell, Santosh Kumar Goru, Luisa Ulloa Severino, Monica F. Tolosa, Paraish S. Misra, Caitríona M. McEvoy, Tania Christova, Yong Liu, Cassandra Atin, Johnny Zhang, Catherine Hu, Noah Vukosa, Xiaolan Chen, Adriana Krizova, Anish Kirpalani, Alex Gregorieff, Ruoyu Ni, Kin Chan, Mandeep K. Gill, Liliana Attisano, Jeffrey L. Wrana, Darren A. Yuen
Publikováno v:
Science Translational Medicine. 14
Fibrosis is a central pathway that drives progression of multiple chronic diseases, yet few safe and effective clinical antifibrotic therapies exist. In most fibrotic disorders, transforming growth factor–β (TGF-β)–driven scarring is an importa
Publikováno v:
Transplantation. 106(5)
The humoral response to two doses of SARS-CoV-2 (Covid-19) vaccine among transplant recipients is inferior to immunocompetent individuals.1 Data on the ‘real-world’ effectiveness of vaccination in kidney transplant recipients [KTRs] are lacking.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4ec0f7d3d032ebc143c92ff160208073
https://doi.org/10.1101/2021.09.21.21263457
https://doi.org/10.1101/2021.09.21.21263457
Autor:
Lauren Caldwell, Kevin D. Burns, Kin Chan, Jeffrey L. Wrana, Darren A. Yuen, Richard E. Gilbert, Paraish S. Misra
Publikováno v:
Canadian Journal of Diabetes
Objectives Diabetes is associated with adverse outcomes, including death, after coronavirus disease 19 (COVID-19) infection. Beyond the lungs, Severe Acute Respiratory Syndrome Coronavirus-2 (SARS-CoV-2), the etiologic agent of the COVID-19 pandemic,
Publikováno v:
Transplantation. 105:S14-S15
Autor:
Paraish S. Misra, M. Cristina Nostro
Publikováno v:
Cell stem cell. 26(4)
Summary The existence of an endocrine progenitor in the adult mouse pancreas has been controversial. Recently in Cell, Wang et al. (2020) use the cell-surface marker Procr to define a population of cells within the adult islet of Langerhans that is c