Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Parag Mahanti"'
Autor:
Cassandra Coburn, Erik Allman, Parag Mahanti, Alexandre Benedetto, Filipe Cabreiro, Zachary Pincus, Filip Matthijssens, Caroline Araiz, Abraham Mandel, Manolis Vlachos, Sally-Anne Edwards, Grahame Fischer, Alexander Davidson, Rosina E Pryor, Ailsa Stevens, Frank J Slack, Nektarios Tavernarakis, Bart P Braeckman, Frank C Schroeder, Keith Nehrke, David Gems
Publikováno v:
PLoS Biology, Vol 11, Iss 7, p e1001613 (2013)
For cells the passage from life to death can involve a regulated, programmed transition. In contrast to cell death, the mechanisms of systemic collapse underlying organismal death remain poorly understood. Here we present evidence of a cascade of cel
Externí odkaz:
https://doaj.org/article/b5384d0af3b54c4ea29373242cae6123
Autor:
Jagan Srinivasan, Stephan H von Reuss, Neelanjan Bose, Alon Zaslaver, Parag Mahanti, Margaret C Ho, Oran G O'Doherty, Arthur S Edison, Paul W Sternberg, Frank C Schroeder
Publikováno v:
PLoS Biology, Vol 10, Iss 1, p e1001237 (2012)
The nematode C. elegans is an important model for the study of social behaviors. Recent investigations have shown that a family of small molecule signals, the ascarosides, controls population density sensing and mating behavior. However, despite exte
Externí odkaz:
https://doaj.org/article/7345f089cb33440abfaa83f036afae50
Autor:
Fatma Kaplan, Jagan Srinivasan, Parag Mahanti, Ramadan Ajredini, Omer Durak, Rathika Nimalendran, Paul W Sternberg, Peter E A Teal, Frank C Schroeder, Arthur S Edison, Hans T Alborn
Publikováno v:
PLoS ONE, Vol 6, Iss 3, p e17804 (2011)
The ascarosides form a family of small molecules that have been isolated from cultures of the nematode Caenorhabditis elegans. They are often referred to as "dauer pheromones" because most of them induce formation of long-lived and highly stress resi
Externí odkaz:
https://doaj.org/article/2acec5cfb67743e0806ffbc5a4444619
Autor:
Sarah M Cohen, Paul W. Sternberg, Henry H. Le, Oishika Panda, Allison E. Akagi, Joshua C. Judkins, Alexander B. Artyukhin, Parag Mahanti, Frank C. Schroeder
The nematode Caenorhabditis elegans uses simple building blocks from primary metabolism and a strategy of modular assembly to build a great diversity of signaling molecules, the ascarosides, which function as a chemical language in this model organis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bfc7d602b632aec0104544fb6673412a
https://resolver.caltech.edu/CaltechAUTHORS:20170410-105746372
https://resolver.caltech.edu/CaltechAUTHORS:20170410-105746372
Autor:
Sydney L. Campbell, Kathleen J. Dumas, Joshua C. Judkins, Anna M. Zimmerman, Adam Antebi, Frank C. Schroeder, Joshua Wollam, Parag Mahanti, Axel Bethke, Patrick J. Hu, Neelanjan Bose
Publikováno v:
Cell Metab
SummarySmall-molecule ligands of nuclear hormone receptors (NHRs) govern the transcriptional regulation of metazoan development, cell differentiation, and metabolism. However, the physiological ligands of many NHRs remain poorly characterized, primar
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2cbdcf6b9f4909acf5843300192a6971
Autor:
Rabia U. Malik, Parag Mahanti, Donha Park, Frank C. Schroeder, Anna Zimmermann, Andreas H. Ludewig, Donald L. Riddle, Frank Doering, Bennett W. Fox, Axel Bethke, Yevgeniy Izrayelit
Publikováno v:
Proceedings of the National Academy of Sciences. 110:5522-5527
Lifespan in Caenorhabditis elegans , Drosophila , and mice is regulated by conserved signaling networks, including the insulin/insulin-like growth factor 1 (IGF-1) signaling cascade and pathways depending on sirtuins, a family of NAD + -dependent dea
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0fbc9d6879b9732228fbca7f96082a48
https://doi.org/10.1073/pnas.1214467110
https://doi.org/10.1073/pnas.1214467110
Publikováno v:
PMC
Discrimination between pathogenic and beneficial microbes is essential for host organism immunity and homeostasis. Here, we show that chemosensory detection of two secondary metabolites produced by Pseudomonas aeruginosa modulates a neuroendocrine si
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::194e4658c6950ee96ac6af0b4c0f893e
https://pubmed.ncbi.nlm.nih.gov/25525785
https://pubmed.ncbi.nlm.nih.gov/25525785
Autor:
Joshua C. Judkins, Frank C. Schroeder, Parag Mahanti, Isaiah Yim, Jacob B. Hoffman, Adam Antebi
Publikováno v:
Angew Chem Int Ed Engl
The development and lifespan of C. elegans are controlled by the nuclear hormone receptor DAF-12, an important model for the vertebrate vitamin D and liver X receptors. As with its mammalian homologues, DAF-12 function is regulated by bile acid-like
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d71601e9467d5c8125d9019052f4b59f
https://pubmed.ncbi.nlm.nih.gov/24453122
https://pubmed.ncbi.nlm.nih.gov/24453122
Autor:
Alexandre Benedetto, Ailsa Stevens, Bart P. Braeckman, Cassandra Coburn, Zachary Pincus, M. Vlachos, Sally-Anne Edwards, Keith Nehrke, Nektarios Tavernarakis, David Gems, Rosina Pryor, Frank C. Schroeder, Grahame Fischer, Frank J. Slack, Caroline Araiz, Alexander Davidson, Filip Matthijssens, Parag Mahanti, Filipe Cabreiro, Abraham Mandel, Erik L. Allman
Publikováno v:
PLoS Biology; Vol 11
PLOS BIOLOGY
PLoS Biology
PLoS Biology, Vol 11, Iss 7, p e1001613 (2013)
PLOS BIOLOGY
PLoS Biology
PLoS Biology, Vol 11, Iss 7, p e1001613 (2013)
Death of the nematode Caenorhabditis elegans involves a conserved necrotic cell death cascade which generates endogenous blue anthranilate fluorescence, allowing death to be visualized.
For cells the passage from life to death can involve a regu
For cells the passage from life to death can involve a regu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::30280814cad0275e96bcf0e473da8743
http://hdl.handle.net/10044/1/73527
http://hdl.handle.net/10044/1/73527
SummaryThe recognition of molecular patterns associated with specific pathogens or food sources is fundamental to ecology and plays a major role in the evolution of predator-prey relationships [1]. Recent studies showed that nematodes produce an evol
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7f390a158325d159ee93ee7b4db1c781
https://resolver.caltech.edu/CaltechAUTHORS:20130315-093313407
https://resolver.caltech.edu/CaltechAUTHORS:20130315-093313407