Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Paqui G. Traves"'
Autor:
Rafael Mayoral, Olivia Osborn, Joanne McNelis, Andrew M. Johnson, Da Young Oh, Cristina Llorente Izquierdo, Heekyung Chung, Pingping Li, Paqui G. Traves, Gautam Bandyopadhyay, Ariane R. Pessentheiner, Jachelle M. Ofrecio, Joshua R. Cook, Li Qiang, Domenico Accili, Jerrold M. Olefsky
Publikováno v:
Molecular Metabolism, Vol 4, Iss 5, Pp 378-391 (2015)
Objective: Adipose tissue is the primary site for lipid deposition that protects the organisms in cases of nutrient excess during obesogenic diets. The histone deacetylase Sirtuin 1 (SIRT1) inhibits adipocyte differentiation by targeting the transcri
Externí odkaz:
https://doaj.org/article/aa5602b006754977b466515665297212
Publikováno v:
Frontiers in Endocrinology, Vol 7 (2016)
Obesity is a complex metabolic disorder associated with the development of non-communicable diseases such as cirrhosis, nonalcoholic fatty liver disease (NAFLD) and type 2 diabetes (T2D). In humans and rodents, obesity promotes hepatic steatosis and
Autor:
Cristina M. Ramírez, Marta Torrecilla-Parra, Virginia Pardo-Marqués, Mario Fernández de-Frutos, Ana Pérez-García, Carlos Tabraue, Juan Vladimir de la Rosa, Patricia Martín-Rodriguez, Mercedes Díaz-Sarmiento, Uxue Nuñez, Marta C. Orizaola, Paqui G. Través, Marta Camps, Lisardo Boscá, Antonio Castrillo
Publikováno v:
Frontiers in Endocrinology, Vol 12 (2021)
Macrophages are immune cells that play crucial roles in host defense against pathogens by triggering their exceptional phagocytic and inflammatory functions. Macrophages that reside in healthy tissues also accomplish important tasks to preserve organ
Externí odkaz:
https://doaj.org/article/ea4acb3b988442639352fea5ae961d3d
Autor:
María Pimentel-Santillana, Paqui G. Través, Raquel Pérez-Sen, Esmerilda G. Delicado, Paloma Martín-Sanz, María Teresa Miras-Portugal, Lisardo Boscá
Publikováno v:
Mediators of Inflammation, Vol 2014 (2014)
The nucleotide uridine trisphosphate (UTP) released to the extracellular milieu acts as a signaling molecule via activation of specific pyrimidine receptors (P2Y). P2Y receptors are G protein-coupled receptors expressed in many cell types. These rece
Externí odkaz:
https://doaj.org/article/103443025af84c7ea95c9175cf92240c
Publikováno v:
Mediators of Inflammation, Vol 2012 (2012)
The interaction between tumor progression and innate immune system has been well established in the last years. Indeed, several lines of clinical evidence indicate that immune cells such as tumor-associated macrophages (TAMs) interact with tumor cell
Externí odkaz:
https://doaj.org/article/1aebc1f96c294c2cb057461fd2e584f7