Zobrazeno 1 - 10
of 54
pro vyhledávání: '"Paqui G Través"'
Autor:
Erin D Lew, Jennifer Oh, Patrick G Burrola, Irit Lax, Anna Zagórska, Paqui G Través, Joseph Schlessinger, Greg Lemke
Publikováno v:
eLife, Vol 3 (2014)
The TAM receptor tyrosine kinases Tyro3, Axl, and Mer regulate key features of cellular physiology, yet the differential activities of the TAM ligands Gas6 and Protein S are poorly understood. We have used biochemical and genetic analyses to delineat
Externí odkaz:
https://doaj.org/article/5fea7649da76453ba6611429febbdc74
Autor:
Raquel López-Fontal, Miriam Zeini, Paqui G Través, Mariana Gómez-Ferrería, Ana Aranda, Guillermo T Sáez, Concha Cerdá, Paloma Martín-Sanz, Sonsoles Hortelano, Lisardo Boscá
Publikováno v:
PLoS ONE, Vol 5, Iss 1, p e8710 (2010)
BackgroundThe role of thyroid hormones and their receptors (TR) during liver regeneration after partial hepatectomy (PH) was studied using genetic and pharmacologic approaches. Roles in liver regeneration have been suggested for T3, but there is no c
Externí odkaz:
https://doaj.org/article/2b2b54ad65f54cd09e060e403eb584fa
Autor:
Julie A Di Paolo, Amy Meng, Bernard Murray, Paqui G. Través, Federico Campigotto, René Galien
Publikováno v:
Annals of the Rheumatic Diseases
ObjectiveJanus kinase inhibitors (JAKinibs) are efficacious in rheumatoid arthritis (RA) with variable reported rates of adverse events, potentially related to differential JAK family member selectivity. Filgotinib was compared with baricitinib, tofa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8a3e2584ca5fa719702f7eec30d7c281
http://europepmc.org/articles/PMC8237188
http://europepmc.org/articles/PMC8237188
Autor:
Cristina M. Ramírez, Marta Torrecilla-Parra, Virginia Pardo-Marqués, Mario Fernández de-Frutos, Ana Pérez-García, Carlos Tabraue, Juan Vladimir de la Rosa, Patricia Martín-Rodriguez, Mercedes Díaz-Sarmiento, Uxue Nuñez, Marta C. Orizaola, Paqui G. Través, Marta Camps, Lisardo Boscá, Antonio Castrillo
Publikováno v:
Digital.CSIC. Repositorio Institucional del CSIC
instname
Frontiers in Endocrinology, Vol 12 (2021)
Frontiers in Endocrinology
instname
Frontiers in Endocrinology, Vol 12 (2021)
Frontiers in Endocrinology
© 2021 Ramírez, Torrecilla-Parra, Pardo-Marqués, de-Frutos, Pérez-García, Tabraue, de la Rosa, Martín-Rodriguez, Díaz-Sarmiento, Nuñez, Orizaola, Través, Camps, Boscá and Castrillo.
Macrophages are immune cells that play crucial roles
Macrophages are immune cells that play crucial roles
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f32c8e0afac7b8de3a05abd6418952f7
Autor:
Marta Roche-Molina, Jorge Alegre-Cebollada, Miguel Torres, Luis Jesús Jiménez-Borreguero, Akhila Balachander, Raquel Martínez-de-Mena, Greg Lemke, Andrés Hidalgo, Mario D. Cordero, Juan A. Bernal, Guillermo Reyes, José Ángel Nicolás-Ávila, Lai Guan Ng, Manuel Desco, Silvia G. Priori, Elena Díaz-García, Jackson LiangYao Li, Pura Muñoz-Cánoves, Lorena Cussó, Elena Bonzón-Kulichenko, Fernando García-Marqués, Demetrio J. Santiago, Georgiana Crainiciuc, Héctor Bueno, María Sánchez-Díaz, Carla V. Rothlin, Elías Herrero-Galán, Noelia A-Gonzalez, Lorena Esteban-Martínez, Borja Ibanez, Sandra Martín-Salamanca, Gabriela Guzmán, José Antonio Enríquez, Juan A. Quintana, Jesús Vázquez, Paqui G. Través, Jagoba Larrazabal, Andrés Pun-García, Antonio Castrillo, Ana Victoria Lechuga-Vieco, Andrés González-Guerra, Andrea Rubio-Ponce, Beatriz Castejón-Vega
Publikováno v:
Digital.CSIC. Repositorio Institucional del CSIC
instname
Cell
instname
Cell
Cardiomyocytes are subjected to the intense mechanical stress and metabolic demands of the beating heart. It is unclear whether these cells, which are long-lived and rarely renew, manage to preserve homeostasis on their own. While analyzing macrophag
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4caf2fcf15150f4a98268a0193bb21a6
http://hdl.handle.net/10261/226682
http://hdl.handle.net/10261/226682
Autor:
Greg Lemke, Anna Zagórska, Rafael Mayoral, Paqui G. Través, Lidia Jiménez-García, Patrick Burrola, Bryan L. Copple, Francisco J. Tapia, Jenna D. Strickland
The TAM receptor tyrosine kinases (RTK) Mer and Axl have been implicated in liver disease, yet our understanding of their roles in liver homeostasis and injury is limited. We therefore examined the performance of Mer and Axl mutant mice during aging,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::02dd1ba2f54ba4bdd8f2ff3a068a99aa
https://doi.org/10.1101/2020.03.13.990143
https://doi.org/10.1101/2020.03.13.990143
Autor:
Greg Lemke, Anna Zagórska, Paqui G. Través, Joanne Oh, Lidia Jiménez-García, Jenna D. Strickland, Bryan L. Copple, Rafael Mayoral, Francisco J. Tapia, Patrick Burrola
Publikováno v:
Life Science Alliance
Digital.CSIC. Repositorio Institucional del CSIC
instname
Digital.CSIC. Repositorio Institucional del CSIC
instname
Genome-wide association studies have implicated the TAM receptor tyrosine kinase (RTK) Mer in liver disease, yet our understanding of the role that Mer and its related RTKs Tyro3 and Axl play in liver homeostasis and the response to acute injury is l
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cda7c2200e51d570ca478c1449d99a3e
https://pubmed.ncbi.nlm.nih.gov/32571802
https://pubmed.ncbi.nlm.nih.gov/32571802
Autor:
Beatriz de las Heras, Sandra Herranz, Paqui G. Través, Raquel López-Fontal, Alfonso Luque, María Angeles Higueras, Lidia Jiménez-García, Sonsoles Hortelano
Publikováno v:
ABACUS. Repositorio de Producción Científica
Universidad Europea (UEM)
Universidad Europea (UEM)
Endothelial activation contributes to lung inflammatory disorders by inducing leucocyte recruitment to pulmonary parenchyma. Consequently, vascular-targeted therapies constitute promising strategies for the treatment of inflammatory pathologies. In t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dc2991416974e8894da32f8d42a603c2
https://doi.org/10.1042/bcj20160343
https://doi.org/10.1042/bcj20160343
Autor:
Greg Lemke, Yusuf Tufail, Humberto Leal-Bailey, Lawrence Fourgeaud, Patrick Burrola, Axel Nimmerjahn, Carla V. Rothlin, Paqui G. Través, Perri Callaway, Erin D. Lew, Anna Zagórska
Publikováno v:
Nature. 532:240-244
Microglia are damage sensors for the central nervous system (CNS), and the phagocytes responsible for routine non-inflammatory clearance of dead brain cells. Here we show that the TAM receptor tyrosine kinases Mer and Axl regulate these microglial fu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::957e009ac4fe003fb9a1b6e23706786c
https://doi.org/10.1038/nature17630
https://doi.org/10.1038/nature17630
Autor:
Paqui G. Través, Gautam Bandyopadhyay, Domenico Accili, Li Qiang, Ariane Pessentheiner, Joshua R. Cook, Olivia Osborn, Jerrold M. Olefsky, Jachelle M. Ofrecio, Joanne C. McNelis, Cristina Llorente Izquierdo, Pingping Li, Andrew M.F. Johnson, Heekyung Chung, Da Young Oh, Rafael Mayoral
Publikováno v:
Molecular Metabolism, Vol 4, Iss 5, Pp 378-391 (2015)
Molecular Metabolism
Molecular Metabolism
Objective Adipose tissue is the primary site for lipid deposition that protects the organisms in cases of nutrient excess during obesogenic diets. The histone deacetylase Sirtuin 1 (SIRT1) inhibits adipocyte differentiation by targeting the transcrip
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c031b3fedbf1b35abe6b80b1cc1f430c
https://doi.org/10.1016/j.molmet.2015.02.007
https://doi.org/10.1016/j.molmet.2015.02.007