Zobrazeno 1 - 10
of 59
pro vyhledávání: '"Pappalardo Ms"'
Autor:
Angelo Palmigiano, Corrada Geraci, Grazia M. L. Consoli, Pappalardo Ms, Eva Galante, Salvatore D. Di Puma, Angelo Spadaro, Giuseppe Granata
Publikováno v:
Bioconjugate chemistry 24 (2013): 1710–1720. doi:10.1021/bc400242y
info:cnr-pdr/source/autori:C. Geraci, G. M. L. Consoli, G. Granata, G. Galante, A. Palmigiano, M. Pappalardo, S. D. Di Puma, A. Spadaro/titolo:The first self-adjuvant multicomponent potential vaccine candidates by tethering of four or eight MUC1 antigenic immunodominant PDTRP units on a calixarene platform:synthesis and biological evaluation/doi:10.1021%2Fbc400242y/rivista:Bioconjugate chemistry/anno:2013/pagina_da:1710/pagina_a:1720/intervallo_pagine:1710–1720/volume:24
info:cnr-pdr/source/autori:C. Geraci, G. M. L. Consoli, G. Granata, G. Galante, A. Palmigiano, M. Pappalardo, S. D. Di Puma, A. Spadaro/titolo:The first self-adjuvant multicomponent potential vaccine candidates by tethering of four or eight MUC1 antigenic immunodominant PDTRP units on a calixarene platform:synthesis and biological evaluation/doi:10.1021%2Fbc400242y/rivista:Bioconjugate chemistry/anno:2013/pagina_da:1710/pagina_a:1720/intervallo_pagine:1710–1720/volume:24
MUC1 protein overexpressed in human epithelial carcinoma is a target in development of novel anticancer vaccines. Multiple units of immunodominant B-cell epitope PDTRP MUC1 core sequence were conjugated to calix[4,8]arene platforms containing TLR2 li
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ef0cc1367a093d974a69e76bc2bc2eba
https://doi.org/10.1021/bc400242y
https://doi.org/10.1021/bc400242y
Autor:
Simone Ronsisvalle, Nicole Ronsisvalle, Carmela Parenti, Federica Panarello, Pappalardo Ms, Angelo Spadaro, Giuseppina Aricò, Lorella Pasquinucci
The hypothesis that central analgesia with reduced side effects is obtainable by occupying an ‘allosteric’ site in the MOR ligand binding domain requires the development of new ligands with peculiar pharmacological profile to be used as tools. Ne
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1ec004d7cc5620440e0ab1beb1e684ef
http://hdl.handle.net/20.500.11769/20080
http://hdl.handle.net/20.500.11769/20080
Autor:
Giuseppe Ronsisvalle, Lorella Pasquinucci, Pappalardo Ms, Orazio Prezzavento, Agostino Marrazzo, Vittorio F
Publikováno v:
Il Farmaco. 56:121-125
The results of studies on the design of a heterocyclic scaffold for the dynorphin A pharmacophore and on structure–affinity relationships in the MPCB/CCB series are described. The representative ligands provide insights to binding modes of benzomor
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6ed25f1e3288451f39bcdfcd802cf578
https://doi.org/10.1016/s0014-827x(01)01022-9
https://doi.org/10.1016/s0014-827x(01)01022-9
Autor:
Pappalardo Ms, Valeria Pittalà, Giuseppe Ronsisvalle, Santi Spampinato, Lorella Pasquinucci, Orazio Prezzavento, S. Cacciaguerra, Vittorio F, Agostino Marrazzo
Publikováno v:
Journal of Medicinal Chemistry. 41:1574-1580
A series of (+)-cis-N-normetazocine derivatives has been described, and their affinities for sigma1, sigma2, and phencyclidine (PCP) sites and opioid, muscarinic (M2), dopamine (D2), and serotonin (5-HT2) receptors were evaluated. The effect of the N
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6c3394ec861663f5475e939090fb4a65
https://doi.org/10.1021/jm970333f
https://doi.org/10.1021/jm970333f
Publikováno v:
ChemInform. 22
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4fe3b2d069c30da0a0e769cfdcf5a23f
https://doi.org/10.1002/chin.199134325
https://doi.org/10.1002/chin.199134325
Autor:
Pappalardo Ms, Vittorio F, Orazio Prezzavento, Lorella Pasquinucci, Giuseppe Ronsisvalle, Santi Spampinato, S. Cacciaguerra, Agostino Marrazzo, Valeria Pittalà
Publikováno v:
ChemInform. 29
A series of (+)-cis-N-normetazocine derivatives has been described, and their affinities for σ1, σ2, and phencyclidine (PCP) sites and opioid, muscarinic (M2), dopamine (D2), and serotonin (5-HT2) receptors were evaluated. The effect of the N-subst
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::511202de4f694487c9daac518b47662d
https://doi.org/10.1002/chin.199833189
https://doi.org/10.1002/chin.199833189
Autor:
Renato Bernardini, Rosalba Romeo, Luigi Panza, Giuseppe Ronsisvalle, Angelo Spadaro, Ennio Bousquet, Pappalardo Ms
Publikováno v:
ChemInform. 31
The Tn epitope is one of the tumor associated O-linked cell surface glycopeptides. It is expressed in over 70% of human epithelial cancers such as lung, colon, stomach and breast carcinomas. The glycosidic linkage of the Tn antigen, between N-acetylg
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::bb8e34e5e698d1386f476e95020e2c35
https://doi.org/10.1002/chin.200046241
https://doi.org/10.1002/chin.200046241
Autor:
Agostino Marrazzo, Vittorio F, Orazio Prezzavento, Pappalardo Ms, Lorella Pasquinucci, Giuseppe Ronsisvalle
Publikováno v:
ChemInform. 32
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::01ebab4f0839406b73945652eed4c094
https://doi.org/10.1002/chin.200128288
https://doi.org/10.1002/chin.200128288
Autor:
Corrada Geraci, Angelo Spadaro, Grazia M. L. Consoli, Pappalardo Ms, Eva Galante, Ennio Bousquet
Publikováno v:
Bioconjugate chemistry 19 (2008): 751–758. doi:10.1021/bc700411w
info:cnr-pdr/source/autori:Geraci C.; Consoli G. M. L.; Galante E.; Bousquet E.; Pappalardo M.; Spadaro A./titolo:Calix[4]arene Decorated with Four Tn Antigen Glycomimetic Units and P3CS Immunoadjuvant: Synthesis, Characterization, and Anticancer Immunological Evaluation/doi:10.1021%2Fbc700411w/rivista:Bioconjugate chemistry/anno:2008/pagina_da:751/pagina_a:758/intervallo_pagine:751–758/volume:19
info:cnr-pdr/source/autori:Geraci C.; Consoli G. M. L.; Galante E.; Bousquet E.; Pappalardo M.; Spadaro A./titolo:Calix[4]arene Decorated with Four Tn Antigen Glycomimetic Units and P3CS Immunoadjuvant: Synthesis, Characterization, and Anticancer Immunological Evaluation/doi:10.1021%2Fbc700411w/rivista:Bioconjugate chemistry/anno:2008/pagina_da:751/pagina_a:758/intervallo_pagine:751–758/volume:19
A novel anticancer vaccine candidate built on a nonpeptidic scaffold has been synthesized. Four S-Tn tumor-associated glycomimetic antigens have been clustered onto a calix[4]arene scaffold bearing an immunoadjuvant moiety (P3CS). The immunogenicity
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d1b6924fdd2b18791981b407e6e13d4c
https://pubmed.ncbi.nlm.nih.gov/18293897
https://pubmed.ncbi.nlm.nih.gov/18293897
Autor:
Severo Salvadori, Giuseppe Ronsisvalle, E. Cavicchini, Santi Spampinato, Pappalardo Ms, Vittorio F, Lorella Pasquinucci, Sergio Ferri
Publikováno v:
European Journal of Medicinal Chemistry. 25:29-33
A series of dimeric opioid peptides derived from μ selective compounds was synthesized to investigate whether μ and δ receptors coexist as distinct recognition sites on the same receptor complex. Some compounds were several times more potent than
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::03f36088e0d5efb5103bcb16e12bc9a0
https://doi.org/10.1016/0223-5234(90)90161-u
https://doi.org/10.1016/0223-5234(90)90161-u