Zobrazeno 1 - 10
of 389
pro vyhledávání: '"Papoian, Garegin A."'
We present a multi-resolution methodology for modelling F-actin filaments. It provides detailed microscopic information at the level of individual monomers at a lower computational cost by replacing the monomer-based model in parts of the simulated f
Externí odkaz:
http://arxiv.org/abs/2203.01284
Mechanochemical simulations of actomyosin networks are traditionally based on one-dimensional models of actin filaments having zero width. Here, and in the follow up paper, approaches are presented for more efficient modelling which incorporates stre
Externí odkaz:
http://arxiv.org/abs/2112.01480
Autor:
Ciocanel, Maria-Veronica, Chandrasekaran, Aravind, Mager, Carli, Ni, Qin, Papoian, Garegin, Dawes, Adriana
Cortical actin networks are highly dynamic and play critical roles in shaping the mechanical properties of cells. The actin cytoskeleton undergoes significant reorganization over the course of the cell cycle, when cortical actin transitions between o
Externí odkaz:
http://arxiv.org/abs/2107.14751
Simulating soft matter systems such as the cytoskeleton can enable deep understanding of experimentally observed phenomena. One challenge of modeling such systems is realistic description of the steric repulsion between nearby polymers. Previous mode
Externí odkaz:
http://arxiv.org/abs/2102.11446
Eukaryotic cells are mechanically supported by a polymer network called the cytoskeleton, which consumes chemical energy to dynamically remodel its structure. Recent experiments in vivo have revealed that this remodeling occasionally happens through
Externí odkaz:
http://arxiv.org/abs/2006.01884
Histone variants regulate replication, transcription, DNA damage repair, and chromosome segregation. Though widely accepted as a paradigm, it has not been rigorously demonstrated that histone variants encode unique mechanical properties. Here, we pre
Externí odkaz:
http://arxiv.org/abs/1910.10247
Quantifying entropy production in various active matter phases will open new avenues for probing self-organization principles in these far-from-equilibrium systems. It has been hypothesized that the dissipation of free energy by active matter systems
Externí odkaz:
http://arxiv.org/abs/1902.10323
In modeling the interior of cells by simulating a reaction-diffusion master equation over a grid of compartments, one employs the assumption that the copy numbers of various chemical species are small, discrete quantities. We show that in this case,
Externí odkaz:
http://arxiv.org/abs/1901.10520
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America, 2021 Oct 01. 118(41), 1-12.
Externí odkaz:
https://www.jstor.org/stable/27093388