Zobrazeno 1 - 10
of 448
pro vyhledávání: '"Papkou A"'
Autor:
Papkou, Andrei, Schalkowski, Rebecca, Barg, Mike-Christoph, Koepper, Svenja, Schulenburg, Hinrich
Publikováno v:
Proceedings: Biological Sciences, 2021 Dec . 288(1965), 1-9.
Externí odkaz:
https://www.jstor.org/stable/27151886
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-15 (2020)
Some bacterial lineages appear to be pre-disposed to evolving antibiotic resistance. Here, the authors show that differential expression of an efflux pump causes widespread variation in evolvability across Staphylococcus aureus isolates, and chemical
Externí odkaz:
https://doaj.org/article/57622c4011834f13aa48b1b348252284
Autor:
Papkou, Andrei, Guzella, Thiago, Yang, Wentao, Koepper, Svenja, Pees, Barbara, Schalkowski, Rebecca, Barg, Mike-Christoph, Rosenstiel, Philip C., Teotónio, Henrique, Schulenburg, Hinrich
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America, 2019 Jan . 116(3), 923-928.
Externí odkaz:
https://www.jstor.org/stable/26574119
Akademický článek
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Autor:
Qiue Yang, Mei Li, Owen B. Spiller, Diego O. Andrey, Philip Hinchliffe, Hui Li, Craig MacLean, Pannika Niumsup, Lydia Powell, Manon Pritchard, Andrei Papkou, Yingbo Shen, Edward Portal, Kirsty Sands, James Spencer, Uttapoln Tansawai, David Thomas, Shaolin Wang, Yang Wang, Jianzhong Shen, Timothy Walsh
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-12 (2017)
The plasmid-encoded MCR-1 enzyme modifies bacterial lipid A, thus conferring resistance to the antibiotic colistin. Here, Yang et al. show that MCR-1 expression can decrease in vitro growth rate, fitness and immune stimulation, and can reduce virulen
Externí odkaz:
https://doaj.org/article/a6d761a9e3b7476da168dbb04950f58a
Publikováno v:
In Zoology August 2016 119(4):330-338
A fitness landscape is a biological analogue of a physical landscape, in which each genotype occupies a location whose elevation corresponds to fitness. Theoretical models predict that rugged fitness landscapes with multiple peaks should impair Darwi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7e9db149eaf3a55bb9c484e56d9b7a49
https://doi.org/10.1101/2023.02.27.530293
https://doi.org/10.1101/2023.02.27.530293
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-15 (2020)
Nature Communications
Nature Communications
The rise of antibiotic resistance in many bacterial pathogens has been driven by the spread of a few successful strains, suggesting that some bacteria are genetically pre-disposed to evolving resistance. Here, we test this hypothesis by challenging a
Autor:
Leila Masri, Antoine Branca, Anna E Sheppard, Andrei Papkou, David Laehnemann, Patrick S Guenther, Swantje Prahl, Manja Saebelfeld, Jacqueline Hollensteiner, Heiko Liesegang, Elzbieta Brzuszkiewicz, Rolf Daniel, Nicolaas K Michiels, Rebecca D Schulte, Joachim Kurtz, Philip Rosenstiel, Arndt Telschow, Erich Bornberg-Bauer, Hinrich Schulenburg
Publikováno v:
PLoS Biology, Vol 13, Iss 6, p e1002169 (2015)
Reciprocal coevolution between host and pathogen is widely seen as a major driver of evolution and biological innovation. Yet, to date, the underlying genetic mechanisms and associated trait functions that are unique to rapid coevolutionary change ar
Externí odkaz:
https://doaj.org/article/a5584d330a0e49db9ae582123520340c
Autor:
Antonio Oliver, R. Craig MacLean, Danna R. Gifford, Tom Vogwill, Andrei Papkou, Victoria Furió
Publikováno v:
Nature ecology & evolution
Gifford, D R, Furió, V, Papkou, A, Vogwill, T, Oliver, A & MacLean, R C 2018, ' Identifying and exploiting genes that potentiate the evolution of antibiotic resistance ', Nature Ecology and Evolution, vol. 2, no. 6, pp. 1033-1039 . https://doi.org/10.1038/s41559-018-0547-x
Nature Ecology & Evolution
Gifford, D R, Furió, V, Papkou, A, Vogwill, T, Oliver, A & MacLean, R C 2018, ' Identifying and exploiting genes that potentiate the evolution of antibiotic resistance ', Nature Ecology and Evolution, vol. 2, no. 6, pp. 1033-1039 . https://doi.org/10.1038/s41559-018-0547-x
Nature Ecology & Evolution
Introductory paragraph There is an urgent need to develop novel approaches for predicting and preventing the evolution of antibiotic resistance. Here we show that the ability to evolve de novo resistance to a clinically important β-lactam antibiotic