Zobrazeno 1 - 10
of 319
pro vyhledávání: '"Paper Sessions"'
BACKGROUND: Proteases are increased in IBS patient colonic tissue and have been shown to activate and sensitize nociceptive (pain-sensing) dorsal root ganglia (DRG) neurons. We found that activation of protease activated receptor 2 (PAR2) on DRG neur
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::364eb98c69b16f2688e3a4675e6d1cb4
https://europepmc.org/articles/PMC6508351/
https://europepmc.org/articles/PMC6508351/
Autor:
Daniela Cardoso Umbelino Cavallini, Bruce A. Vallance, J Y Chan, Larissa Sbaglia Celiberto, Lijun Xia, H T Law, K Bhullar
BACKGROUND: Enteric bacterial pathogens are a major cause of diarrheal disease in developed as well as developing countries. To infect their hosts, most pathogens need to directly infect the intestinal epithelium, however to do so, they must cross th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::37bd14abfe3016b5ca1d04a59acdaa98
https://europepmc.org/articles/PMC6508271/
https://europepmc.org/articles/PMC6508271/
BACKGROUND: Due to health and socioeconomic burdens associated with Inflammatory Bowel Disease (IBD), timely access to specialist care is important. In Canada, speciality gastroenterology (GI) care is accessed only by referral. To receive timely care
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b030444553478da8ad8d1de5ab12e2d8
https://europepmc.org/articles/PMC6508406/
https://europepmc.org/articles/PMC6508406/
Autor:
Dominique Lévesque, François-Michel Boisvert, Jean-Philippe Babeu, François Boudreau, Élie Lambert
BACKGROUND: Hepatocyte nuclear factor 4 alpha (HNF4α) is a transcription factor regulating the expression of intestinal epithelial genes. Up to 12 HNF4α isoforms can be produced by the use of promoters P1 and P2, and alternative splicing. HNF4α ha
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e608bc8177d84918f50e0e07d9b72f9c
https://europepmc.org/articles/PMC6508266/
https://europepmc.org/articles/PMC6508266/
BACKGROUND: Low muscle mass (sarcopenia) is associated with increased mortality in patients with cirrhosis. The association of functional performance with sarcopenia and its impact on mortality has not been well established in cirrhosis. AIMS: 1) Det
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::766bc639f7bf2059d10755684bafd0d2
https://europepmc.org/articles/PMC6508311/
https://europepmc.org/articles/PMC6508311/
BACKGROUND: Colonoscopy preparation is challenging, involving the consumption of a large volume of prep solution in the day leading up to procedure. Adequate preparation is vital for the endoscopist to visualize the full colon. Upwards of 20% of outp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b68943eaa1b1720e3b25db366a33eef5
https://europepmc.org/articles/PMC6508346/
https://europepmc.org/articles/PMC6508346/
BACKGROUND: Inflammation is associated with psychiatric illness, and patients with inflammatory bowel disease (IBD) have elevated risk of anxiety and depression. Pregnancy alters immune functioning, and inflammation may result in psychiatric disorder
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a566530629d06dba0b9ffa605fb3c645
https://europepmc.org/articles/PMC6508215/
https://europepmc.org/articles/PMC6508215/
BACKGROUND: Many patients who present with undiagnosed iron deficiency anemia (IDA) are presumed to have occult gastrointestinal (GI) bleeding as the cause. When investigations include a negative upper endoscopy and colonoscopy, a negative celiac ant
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5979e2ade7831929c932c519ba52ffe9
https://europepmc.org/articles/PMC6508280/
https://europepmc.org/articles/PMC6508280/
AIMS: Tests measuring serum adalimumab levels are not widely available. We aim to evaluate whether serum adalimumab levels correlate with disease severity in patients with Crohn disease. Additionally, as the test is expensive, we aim to see if clinic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cb6894296fc8bf7bb591ab3c3ac20f7d
https://europepmc.org/articles/PMC6508221/
https://europepmc.org/articles/PMC6508221/
BACKGROUND: Neonatal low-GGT cholestasis has a unique differential diagnosis centered on congenital disorders of bile acid transport or synthesis. Kabuki syndrome is a genetic condition with distinctive facies, developmental delay, and skeletal, rena
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8b7327a8466c18d324c4c2663bdc8351
https://europepmc.org/articles/PMC6508257/
https://europepmc.org/articles/PMC6508257/