The tumor-derived cytokine Chi3l1 induces neutrophil extracellular traps that promote T cell exclusion in triple-negative breast cancer

Autor: Taifour, Tarek, Attalla, Sherif Samer, Zuo, Dongmei, Gu, Yu, Sanguin-Gendreau, Virginie, Proud, Hailey, Solymoss, Emilie, Bui, Tung, Kuasne, Hellen, Papavasiliou, Vasilios, Lee, Chun Geun, Kamle, Suchitra, Siegel, Peter M., Elias, Jack A., Park, Morag, Muller, William J.

Publikováno v: In Immunity 12 December 2023 56(12):2755-2772

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Translational and HIF-1α-Dependent Metabolic Reprogramming Underpin Metabolic Plasticity and Responses to Kinase Inhibitors and Biguanides

Autor: Hulea, Laura, Gravel, Simon-Pierre, Morita, Masahiro, Cargnello, Marie, Uchenunu, Oro, Im, Young Kyuen, Lehuédé, Camille, Ma, Eric H., Leibovitch, Matthew, McLaughlan, Shannon, Blouin, Marie-José, Parisotto, Maxime, Papavasiliou, Vasilios, Lavoie, Cynthia, Larsson, Ola, Ohh, Michael, Ferreira, Tiago, Greenwood, Celia, Bridon, Gaëlle, Avizonis, Daina, Ferbeyre, Gerardo, Siegel, Peter, Jones, Russell G., Muller, William, Ursini-Siegel, Josie, St-Pierre, Julie, Pollak, Michael, Topisirovic, Ivan

Publikováno v: In Cell Metabolism 4 December 2018 28(6):817-832

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An ErbB2/c-Src axis links bioenergetics with PRC2 translation to drive epigenetic 2 reprogramming and mammary tumourigenesis

Autor: Smith, Harvey W, Hirukawa, Alison, Sanguin-Gendreau, Virginie, Nandi, Ipshita, Dufour, Catherine R, Zuo, Dongmei, Tandoc, Kristofferson, Leibovitch, Matthew, Singh, Salendra, Rennhack, Jonathan, Swiatnicki, Matthew, Lavoie, Cynthia, Papavasiliou, Vasilios, Temps, Carolin, Carragher, Neil, Unciti-Broceta, Asier, Savage, Paul, Basik, Mark, van Hoef, Vincent, Larsson, Ola, Cooper, Caroline L, Calderon, Ana Cristina Vargas, Beith, Jane, Millar, Ewan, Selinger, Christina, Giguère, Vincent, Park, Morag, Harris, Lyndsey R, Varadan, Vinay, Andrechek, Eran, O'Toole, Sandra A, Topisirovic, Ivan, Muller, William J

Publikováno v: Smith, H W, Hirukawa, A, Sanguin-Gendreau, V, Nandi, I, Dufour, C R, Zuo, D, Tandoc, K, Leibovitch, M, Singh, S, Rennhack, J, Swiatnicki, M, Lavoie, C, Papavasiliou, V, Temps, C, Carragher, N, Unciti-Broceta, A, Savage, P, Basik, M, van Hoef, V, Larsson, O, Cooper, C L, Calderon, A C V, Beith, J, Millar, E, Selinger, C, Giguère, V, Park, M, Harris, L R, Varadan, V, Andrechek, E, O'Toole, S A, Topisirovic, I & Muller, W J 2019, ' An ErbB2/c-Src axis links bioenergetics with PRC2 translation to drive epigenetic 2 reprogramming and mammary tumourigenesis ', Nature Communications . https://doi.org/10.1038/s41467-019-10681-4

Dysregulation of histone modifications promotes carcinogenesis by altering transcription. Breast cancers frequently overexpress the histone methyltransferase EZH2, the catalytic subunit of Polycomb Repressor Complex 2 (PRC2). However, the role of EZH

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od______3094::02577d115160bd49655e9dec3d10a333
https://hdl.handle.net/20.500.11820/f8ed5961-3469-4b56-a87f-2b4be06c7021