Mapping genomic loci implicates genes and synaptic biology in schizophrenia.

Autor: Trubetskoy V; Department of Psychiatry and Psychotherapy, Charité - Universitätsmedizin, Berlin, Germany., Pardiñas AF; MRC Centre for Neuropsychiatric Genetics and Genomics, Division of Psychological Medicine and Clinical Neurosciences, Cardiff University, Cardiff, UK., Qi T; Institute for Molecular Bioscience, University of Queensland, Brisbane, Queensland, Australia.; School of Life Sciences, Westlake University, Hangzhou, China., Panagiotaropoulou G; Department of Psychiatry and Psychotherapy, Charité - Universitätsmedizin, Berlin, Germany., Awasthi S; Department of Psychiatry and Psychotherapy, Charité - Universitätsmedizin, Berlin, Germany., Bigdeli TB; Department of Psychiatry and the Behavioral Sciences, SUNY Downstate Medical Center, New York, NY, USA.; Institute for Genomic Health, SUNY Downstate Medical Center, New York, NY, USA.; Department of Psychiatry, Veterans Affairs New York Harbor Healthcare System, New York, NY, USA., Bryois J; Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden., Chen CY; Biogen, Cambridge, MA, USA.; Analytic and Translational Genetics Unit, Massachusetts General Hospital, Boston, MA, USA.; Psychiatric and Neurodevelopmental Genetics Unit, Center for Genomic Medicine, Massachusetts General Hospital, Boston, MA, USA., Dennison CA; MRC Centre for Neuropsychiatric Genetics and Genomics, Division of Psychological Medicine and Clinical Neurosciences, Cardiff University, Cardiff, UK., Hall LS; MRC Centre for Neuropsychiatric Genetics and Genomics, Division of Psychological Medicine and Clinical Neurosciences, Cardiff University, Cardiff, UK., Lam M; Stanley Center for Psychiatric Research, Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Research Division, Institute of Mental Health, Singapore, Republic of Singapore.; Division of Psychiatry Research, Zucker Hillside Hospital, Glen Oaks, NY, USA., Watanabe K; Department of Complex Trait Genetics, Center for Neurogenomics and Cognitive Research, Amsterdam Neuroscience, Vrije Universiteit Amsterdam, Amsterdam, The Netherlands., Frei O; NORMENT Centre, Division of Mental Health and Addiction, University of Oslo, Oslo, Norway.; Division of Mental Health and Addiction, Oslo University Hospital, Oslo, Norway.; Center for Bioinformatics, Department of Informatics, University of Oslo, Oslo, Norway., Ge T; Psychiatric and Neurodevelopmental Genetics Unit, Center for Genomic Medicine, Massachusetts General Hospital, Boston, MA, USA.; Stanley Center for Psychiatric Research, Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Department of Psychiatry, Harvard Medical School, Boston, MA, USA., Harwood JC; MRC Centre for Neuropsychiatric Genetics and Genomics, Division of Psychological Medicine and Clinical Neurosciences, Cardiff University, Cardiff, UK., Koopmans F; Department of Molecular and Cellular Neurobiology, Center for Neurogenomics and Cognitive Research, Faculty of Science, Amsterdam Neuroscience, Vrije Universiteit, Amsterdam, The Netherlands., Magnusson S; deCODE Genetics, Amgen, Reykjavik, Iceland., Richards AL; MRC Centre for Neuropsychiatric Genetics and Genomics, Division of Psychological Medicine and Clinical Neurosciences, Cardiff University, Cardiff, UK., Sidorenko J; Institute for Molecular Bioscience, University of Queensland, Brisbane, Queensland, Australia., Wu Y; Institute for Molecular Bioscience, University of Queensland, Brisbane, Queensland, Australia., Zeng J; Institute for Molecular Bioscience, University of Queensland, Brisbane, Queensland, Australia., Grove J; The Lundbeck Foundation Initiative for Integrative Psychiatric Research (iPSYCH), Aarhus, Denmark.; Department of Biomedicine and Centre for Integrative Sequencing (iSEQ), Aarhus University, Aarhus, Denmark.; Center for Genomics and Personalized Medicine, Aarhus, Denmark., Kim M; Department of Psychiatry, Semel Institute, David Geffen School of Medicine, University of California Los Angeles, Los Angeles, CA, USA., Li Z; Affiliated Hospital of Qingdao University and Biomedical Sciences Institute of Qingdao University (Qingdao Branch of SJTU Bio-X Institutes), Qingdao University, Qingdao, China.; Bio-X Institutes, Key Laboratory for the Genetics of Developmental and Neuropsychiatric Disorders (Ministry of Education), Collaborative Innovation Center for Brain Science, Shanghai Jiao Tong University, Shanghai, China., Voloudakis G; Department of Psychiatry, Pamela Sklar Division of Psychiatric Genomics, Friedman Brain Institute, Department of Genetics and Genomic Science and Institute for Data Science and Genomic Technology, Icahn School of Medicine at Mount Sinai, New York, NY, USA., Zhang W; Department of Psychiatry, Pamela Sklar Division of Psychiatric Genomics, Friedman Brain Institute, Department of Genetics and Genomic Science and Institute for Data Science and Genomic Technology, Icahn School of Medicine at Mount Sinai, New York, NY, USA.; Department of Genetics and Genomic Sciences and Institute for Genomics and Multiscale Biology, Icahn School of Medicine at Mount Sinai, New York, NY, USA., Adams M; Division of Psychiatry, Centre for Clinical Brain Sciences, University of Edinburgh, Royal Edinburgh Hospital, Edinburgh, UK., Agartz I; NORMENT Centre, Division of Mental Health and Addiction, University of Oslo, Oslo, Norway.; Department of Psychiatric Research, Diakonhjemmet Hospital, Oslo, Norway.; Centre for Psychiatry Research, Department of Clinical Neuroscience, Karolinska Institutet and Stockholm Health Care Services, Stockholm Region, Stockholm, Sweden., Atkinson EG; Analytic and Translational Genetics Unit, Massachusetts General Hospital, Boston, MA, USA.; Stanley Center for Psychiatric Research, Broad Institute of MIT and Harvard, Cambridge, MA, USA., Agerbo E; The Lundbeck Foundation Initiative for Integrative Psychiatric Research (iPSYCH), Aarhus, Denmark.; National Centre for Register-based Research, Aarhus University, Aarhus, Denmark., Al Eissa M; Molecular Psychiatry Laboratory, Division of Psychiatry, University College London, London, UK., Albus M; Comedicum Lindwurmhof, Munich, Germany., Alexander M; Center for Depression, Anxiety and Stress Research, McLean Hospital, Belmont, MA, USA., Alizadeh BZ; University Medical Center Groningen, University Center for Psychiatry, Rob Giel Research Center, University of Groningen, Groningen, The Netherlands.; Department of Epidemiology, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands., Alptekin K; Department of Psychiatry, Dokuz Eylül University School of Medicine, Izmir, Turkey.; Department of Neuroscience, Dokuz Eylül University Graduate School of Health Sciences, Izmir, Turkey., Als TD; The Lundbeck Foundation Initiative for Integrative Psychiatric Research (iPSYCH), Aarhus, Denmark.; Department of Biomedicine and Centre for Integrative Sequencing (iSEQ), Aarhus University, Aarhus, Denmark.; Center for Genomics and Personalized Medicine, Aarhus, Denmark., Amin F; Department of Psychiatry and Behavioral Sciences, Emory University, Atlanta, GA, USA., Arolt V; Department of Psychiatry, University of Münster, Münster, Germany., Arrojo M; Servizo de Psiquiatría, Complexo Hospitalario Universitario de Santiago de Compostela, Servizo Galego de Saúde (SERGAS), Santiago de Compostela, Spain., Athanasiu L; NORMENT Centre, Division of Mental Health and Addiction, University of Oslo, Oslo, Norway.; Division of Mental Health and Addiction, Oslo University Hospital, Oslo, Norway., Azevedo MH; Institute of Medical Psychology, Faculty of Medicine, University of Coimbra, Coimbra, Portugal., Bacanu SA; Virginia Institute for Psychiatric and Behavioral Genetics, Department of Psychiatry, Virginia Commonwealth University, Richmond, VA, USA., Bass NJ; Molecular Psychiatry Laboratory, Division of Psychiatry, University College London, London, UK., Begemann M; Clinical Neuroscience, Max Planck Institute of Experimental Medicine, Göttingen, Germany., Belliveau RA; Stanley Center for Psychiatric Research, Broad Institute of MIT and Harvard, Cambridge, MA, USA., Bene J; Department of Medical Genetics, Medical School, University of Pécs, Pécs, Hungary., Benyamin B; Australian Centre for Precision Health, University of South Australia Cancer Research Institute, University of South Australia, Adelaide, South Australia, Australia.; UniSA Allied Health and Human Performance, University of South Australia, Adelaide, South Australia, Australia.; South Australian Health and Medical Research Institute, Adelaide, South Australia, Australia., Bergen SE; Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden., Blasi G; Department of Basic Medical Science, Neuroscience and Sense Organs, University of Bari 'Aldo Moro', Bari, Italy., Bobes J; Área de Psiquiatría-Universidad de Oviedo, Hospital Universitario Central de Asturias (HUCA), Asturias, Spain.; Instituto de Investigación Sanitaria del Principado de Asturias (ISPA), Oviedo, Asturias, Spain.; Centro de Investigación Biomédica en Red de Salud Mental, Oviedo, Asturias, Spain., Bonassi S; Unit of Clinical and Molecular Epidemiology, IRCCS San Raffaele Roma and San Raffaele University, Rome, Italy., Braun A; Department of Psychiatry and Psychotherapy, Charité - Universitätsmedizin, Berlin, Germany., Bressan RA; Department of Psychiatry, Universidade Federal de São Paulo, São Paulo, Brazil.; Laboratory of Integrative Neuroscience, Universidade Federal de São Paulo, São Paulo, Brazil., Bromet EJ; Department of Psychiatry and Behavioural Health, Stony Brook University, Stony Brook, NY, USA., Bruggeman R; University Medical Center Groningen, University Center for Psychiatry, Rob Giel Research Center, University of Groningen, Groningen, The Netherlands.; Department of Clinical and Developmental Neuropsychology, University of Groningen, Groningen, The Netherlands., Buckley PF; Health Science Center, University of Tennessee, Memphis, TN, USA., Buckner RL; Department of Psychology, Harvard University, Cambridge, MA, USA., Bybjerg-Grauholm J; The Lundbeck Foundation Initiative for Integrative Psychiatric Research (iPSYCH), Aarhus, Denmark.; Center for Neonatal Screening, Department for Congenital Disorders, Statens Serum Institut, Copenhagen, Denmark., Cahn W; University Medical Center Utrecht, Department of Psychiatry, Rudolf Magnus Institute of Neuroscience, Utrecht, The Netherlands.; Altrecht, General Menthal Health Care, Utrecht, The Netherlands., Cairns MJ; School of Biomedical Sciences and Pharmacy, University of Newcastle, Newcastle, New South Wales, Australia.; Hunter Medical Research Institute, Newcastle, New South Wales, Australia.; Centre for Brain and Mental Health Research, University of Newcastle, Newcastle, New South Wales, Australia., Calkins ME; Department of Psychiatry, University of Pennsylvania, Philadelphia, PA, USA., Carr VJ; School of Psychiatry, University of New South Wales, Sydney, New South Wales, Australia.; Department of Psychiatry, Monash University, Melbourne, Victoria, Australia.; Neuroscience Research Australia, Sydney, New South Wales, Australia., Castle D; Department of Psychiatry, University of Melbourne, Parkville, Victoria, Australia.; St Vincent's Hospital, Melbourne, Victoria, Australia., Catts SV; Brain and Mind Centre, The University of Sydney, Sydney, New South Wales, Australia.; School of Medicine, University of Queensland, Herston, Queensland, Australia., Chambert KD; Stanley Center for Psychiatric Research, Broad Institute of MIT and Harvard, Cambridge, MA, USA., Chan RCK; Institute of Psychology, Chinese Academy of Science, Beijing, China.; Department of Psychology, University of Chinese Academy of Sciences, Beijing, China., Chaumette B; INSERM U1266, Institute of Psychiatry and Neuroscience of Paris, Université de Paris, GHU Paris Psychiatrie & Neurosciences, Paris, France.; Department of Psychiatry, McGill University, Montreal, Québec, Canada., Cheng W; Department of Computer Science, University of North Carolina, Chapel Hill, NC, USA., Cheung EFC; Castle Peak Hospital, Hong Kong, China., Chong SA; Research Division, Institute of Mental Health, Singapore, Republic of Singapore.; Saw Swee Hock School of Public Health, National University of Singapore, Singapore, Republic of Singapore., Cohen D; Faculté de Médecine Sorbonne Université, Groupe de Recherche Clinique no. 15 - Troubles Psychiatriques et Développement (PSYDEV), Department of Child and Adolescent Psychiatry, Hôpital Universitaire de la Pitié-Salpêtrière, Paris, France.; Centre de Référence des Maladies Rares à Expression Psychiatrique, Department of Child and Adolescent Psychiatry, AP-HP Sorbonne Université, Hôpital Universitaire de la Pitié-Salpêtrière, Paris, France.; Institut des Systèmes Intelligents et de Robotique (ISIR), CNRS UMR7222, Faculté des Sciences et Ingénierie, Sorbonne Université, Paris, France., Consoli A; Faculté de Médecine Sorbonne Université, Groupe de Recherche Clinique no. 15 - Troubles Psychiatriques et Développement (PSYDEV), Department of Child and Adolescent Psychiatry, Hôpital Universitaire de la Pitié-Salpêtrière, Paris, France.; Centre de Référence des Maladies Rares à Expression Psychiatrique, Department of Child and Adolescent Psychiatry, AP-HP Sorbonne Université, Hôpital Universitaire de la Pitié-Salpêtrière, Paris, France., Cordeiro Q; Department of Psychiatry, Irmandade da Santa Casa de Misericórdia de São Paulo, São Paulo, Brazil., Costas J; Instituto de Investigación Sanitaria (IDIS) de Santiago de Compostela, Complexo Hospitalario Universitario de Santiago de Compostela (CHUS), Servizo Galego de Saúde (SERGAS), Santiago de Compostela, Spain., Curtis C; Social, Genetic and Developmental Psychiatry Centre, Institute of Psychiatry, Psychology and Neuroscience, King's College London, London, UK.; National Institute for Health Research (NIHR) Maudsley Biomedical Research Centre at South London and Maudsley NHS Foundation Trust and King's College London, London, UK., Davidson M; University of Nicosia Medical School, Nicosia, Cyprus., Davis KL; Department of Psychiatry, Icahn School of Medicine at Mount Sinai, New York, NY, USA., de Haan L; Department of Psychiatry, Academic Medical Centre, University of Amsterdam, Amsterdam, The Netherlands.; Arkin, Institute for Mental Health, Amsterdam, The Netherlands., Degenhardt F; Institute of Human Genetics, University of Bonn, Bonn, Germany., DeLisi LE; Department of Psychiatry, Harvard Medical School, Boston, MA, USA.; Cambridge Health Alliance, Cambridge, MA, USA., Demontis D; The Lundbeck Foundation Initiative for Integrative Psychiatric Research (iPSYCH), Aarhus, Denmark.; Department of Biomedicine and Centre for Integrative Sequencing (iSEQ), Aarhus University, Aarhus, Denmark.; Center for Genomics and Personalized Medicine, Aarhus, Denmark., Dickerson F; Sheppard Pratt Health System, Baltimore, MD, USA., Dikeos D; First Department of Psychiatry, Medical School, National and Kapodistrian University of Athens, Eginition Hospital, Athens, Greece., Dinan T; Department of Psychiatry and Neurobehavioural Sciences, University College Cork, Cork, Ireland.; APC Microbiome Ireland, University College Cork, Cork, Ireland., Djurovic S; NORMENT Centre, Department of Clinical Science, University of Bergen, Bergen, Norway.; Department of Medical Genetics, Oslo University Hospital, Oslo, Norway., Duan J; Center for Psychiatric Genetics, NorthShore University HealthSystem, Evanston, IL, USA.; Department of Psychiatry and Behavioral Neurosciences, The University of Chicago, Chicago, IL, USA., Ducci G; Department of Mental Health, ASL Rome 1, Rome, Italy., Dudbridge F; Department of Health Sciences, University of Leicester, Leicester, UK., Eriksson JG; Department of General Practice and Primary Health Care, University of Helsinki and Helsinki University Hospital, Helsinki, Finland.; Folkhälsan Research Center, Helsinki, Finland.; Department of Obstetrics and Gynecology, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Republic of Singapore., Fañanás L; Department of Evolutionary Biology, Ecology and Environmental Sciences, Faculty of Biology, University of Barcelona, Barcelona, Spain.; Centro de Investigación Biomédica en Red en Salud Mental (CIBERSAM), Madrid, Spain., Faraone SV; Departments of Psychiatry and Neuroscience and Physiology, SUNY Upstate Medical University, Syracuse, NY, USA., Fiorentino A; Molecular Psychiatry Laboratory, Division of Psychiatry, University College London, London, UK., Forstner A; Institute of Human Genetics, University of Bonn, Bonn, Germany.; Centre for Human Genetics, University of Marburg, Marburg, Germany., Frank J; Department of Genetic Epidemiology in Psychiatry, Central Institute of Mental Health, Medical Faculty Mannheim, University of Heidelberg, Mannheim, Germany., Freimer NB; Department of Human Genetics, David Geffen School of Medicine, University of California Los Angeles, Los Angeles, CA, USA.; Department of Psychiatry and Biobehavioral Sciences, University of California Los Angeles, Los Angeles, CA, USA., Fromer M; Division of Psychiatric Genomics, Department of Psychiatry, Icahn School of Medicine at Mount Sinai, New York, NY, USA., Frustaci A; Barnet, Enfield and Haringey Mental Health NHS Trust, St Ann's Hospital, London, UK., Gadelha A; Department of Psychiatry, Universidade Federal de São Paulo, São Paulo, Brazil.; Laboratory of Integrative Neuroscience, Universidade Federal de São Paulo, São Paulo, Brazil., Genovese G; Stanley Center for Psychiatric Research, Broad Institute of MIT and Harvard, Cambridge, MA, USA., Gershon ES; Departments of Psychiatry and Human Genetics, University of Chicago, Chicago, IL, USA., Giannitelli M; Faculté de Médecine Sorbonne Université, Groupe de Recherche Clinique no. 15 - Troubles Psychiatriques et Développement (PSYDEV), Department of Child and Adolescent Psychiatry, Hôpital Universitaire de la Pitié-Salpêtrière, Paris, France.; Centre de Référence des Maladies Rares à Expression Psychiatrique, Department of Child and Adolescent Psychiatry, AP-HP Sorbonne Université, Hôpital Universitaire de la Pitié-Salpêtrière, Paris, France., Giegling I; Department of Psychiatry and Psychotherapy, Medical University of Vienna, Vienna, Austria., Giusti-Rodríguez P; Department of Genetics, University of North Carolina, Chapel Hill, NC, USA., Godard S; Departments of Psychiatry and Human and Molecular Genetics, INSERM, Institut de Myologie, Hôpital de la Pitiè-Salpêtrière, Paris, France., Goldstein JI; Analytic and Translational Genetics Unit, Massachusetts General Hospital, Boston, MA, USA., González Peñas J; Centro de Investigación Biomédica en Red en Salud Mental (CIBERSAM), Madrid, Spain.; Department of Child and Adolescent Psychiatry, Institute of Psychiatry and Mental Health, General Universitario Gregorio Marañón, School of Medicine, Universidad Complutense, IiSGM, Madrid, Spain., González-Pinto A; Centro de Investigación Biomédica en Red en Salud Mental (CIBERSAM), Madrid, Spain.; BIOARABA Health Research Institute, OSI Araba, University Hospital, University of the Basque Country, Vitoria, Spain., Gopal S; Neuroscience Therapeutic Area, Janssen Research and Development, Titusville, NJ, USA., Gratten J; Institute for Molecular Bioscience, University of Queensland, Brisbane, Queensland, Australia.; Mater Research Institute, University of Queensland, Brisbane, Queensland, Australia., Green MF; Department of Psychiatry and Biobehavioral Sciences, Geffen School of Medicine, University of California Los Angeles, Los Angeles, CA, USA.; VA Greater Los Angeles Healthcare System, Los Angeles, CA, USA., Greenwood TA; Department of Psychiatry, University of California San Diego, La Jolla, CA, USA., Guillin O; INSERM, Rouen, France.; Centre Hospitalier du Rouvray, Rouen, France.; UFR Santé, Université de Rouen Normandie, Rouen, France., Gülöksüz S; Department of Psychiatry and Neuropsychology, School for Mental Health and Neuroscience, Maastricht University Medical Centre, Maastricht, The Netherlands.; Department of Psychiatry, Yale School of Medicine, New Haven, CT, USA., Gur RE; Department of Psychiatry, University of Pennsylvania, Philadelphia, PA, USA., Gur RC; Department of Psychiatry, University of Pennsylvania, Philadelphia, PA, USA., Gutiérrez B; Department of Psychiatry, Faculty of Medicine and Biomedical Research Centre (CIBM), University of Granada, Granada, Spain., Hahn E; Department of Psychiatry, Charité - Universitätsmedizin, Berlin, Germany., Hakonarson H; Children's Hospital of Philadelphia, Leonard Madlyn Abramson Research Center, Philadelphia, PA, USA., Haroutunian V; Department of Psychiatry, Icahn School of Medicine at Mount Sinai, New York, NY, USA.; Department of Neuroscience, Icahn School of Medicine at Mount Sinai, New York, NY, USA.; Mental Illness Research Clinical and Education Center (MIRECC), JJ Peters VA Medical Center, New York, NY, USA., Hartmann AM; Department of Psychiatry and Psychotherapy, Medical University of Vienna, Vienna, Austria., Harvey C; Department of Psychiatry, University of Melbourne, Parkville, Victoria, Australia.; NorthWestern Mental Health, Melbourne, Victoria, Australia., Hayward C; MRC Human Genetics Unit, University of Edinburgh, Institute of Genetics and Cancer, Western General Hospital, Edinburgh, UK., Henskens FA; School of Medicine and Public Health, University of Newcastle, Newcastle, New South Wales, Australia., Herms S; Division of Medical Genetics, Department of Biomedicine, University of Basel, Basel, Switzerland., Hoffmann P; Division of Medical Genetics, Department of Biomedicine, University of Basel, Basel, Switzerland., Howrigan DP; Analytic and Translational Genetics Unit, Massachusetts General Hospital, Boston, MA, USA.; Broad Institute of MIT and Harvard, Cambridge, MA, USA., Ikeda M; Department of Psychiatry, Fujita Health University School of Medicine, Toyoake Aichi, Japan., Iyegbe C; Department of Psychosis Studies, Institute of Psychiatry, Psychology and Neuroscience, King's College London, London, UK., Joa I; Regional Centre for Clinical Research in Psychosis, Department of Psychiatry, Stavanger University Hospital, Stavanger, Norway., Julià A; Rheumatology Research Group, Vall d'Hebron Research Institute, Barcelona, Spain., Kähler AK; Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden., Kam-Thong T; Roche Pharma Research and Early Development, Pharmaceutical Sciences, Roche Innovation Center Basel, F. Hoffman-La Roche, Basel, Switzerland., Kamatani Y; Laboratory of Complex Trait Genomics, Department of Computational Biology and Medical Sciences, Graduate School of Frontier Sciences, The University of Tokyo, Tokyo, Japan.; Laboratory for Statistical Analysis, RIKEN Center for Integrative Medical Sciences, Yokohama, Japan., Karachanak-Yankova S; Department of Medical Genetics, Medical University, Sofia, Bulgaria.; Department of Genetics, Faculty of Biology, Sofia University 'St. Kliment Ohridski', Sofia, Bulgaria., Kebir O; INSERM U1266, Institute of Psychiatry and Neuroscience of Paris, Université de Paris, GHU Paris Psychiatrie & Neurosciences, Paris, France., Keller MC; Institute for Behavioural Genetics, University of Colorado Boulder, Boulder, CO, USA., Kelly BJ; School of Medicine and Public Health, University of Newcastle, Newcastle, New South Wales, Australia., Khrunin A; Institute of Molecular Genetics of National Research Centre 'Kurchatov Institute', Moscow, Russia., Kim SW; Department of Psychiatry, Chonnam National University Medical School, Gwangju, Korea., Klovins J; Latvian Biomedical Research and Study Centre, Riga, Latvia., Kondratiev N; Mental Health Research Center, Moscow, Russian Federation., Konte B; Department of Psychiatry and Psychotherapy, Medical University of Vienna, Vienna, Austria., Kraft J; Department of Psychiatry and Psychotherapy, Charité - Universitätsmedizin, Berlin, Germany.; Berlin School of Mind and Brain, Humboldt-Universität zu Berlin, Berlin, Germany., Kubo M; RIKEN Center for Integrative Medical Sciences, Yokohama, Japan., Kučinskas V; Faculty of Medicine, Vilnius University, Vilnius, Lithuania., Kučinskiene ZA; Faculty of Medicine, Vilnius University, Vilnius, Lithuania., Kusumawardhani A; Psychiatry Department, University of Indonesia - Cipto Mangunkusumo National General Hospital, Jakarta, Indonesia., Kuzelova-Ptackova H; Department of Psychiatry, 1st Faculty of Medicine and General University Hospital, Prague, Czech Republic., Landi S; Dipartimento di Biologia, Universita' di Pisa, Pisa, Italy., Lazzeroni LC; Department of Psychiatry and Behavioral Sciences, Stanford University, Stanford, CA, USA.; Department of Biomedical Data Science, Stanford University, Stanford, CA, USA., Lee PH; Stanley Center for Psychiatric Research, Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Psychiatric and Neurodevelopmental Genetics Unit, Department of Psychiatry and Center for Genomic Medicine, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA., Legge SE; MRC Centre for Neuropsychiatric Genetics and Genomics, Division of Psychological Medicine and Clinical Neurosciences, Cardiff University, Cardiff, UK., Lehrer DS; Department of Psychiatry, Wright State University, Dayton, OH, USA., Lencer R; Department of Psychiatry, University of Münster, Münster, Germany., Lerer B; Department of Psychiatry, Hadassah-Hebrew University Medical Center, Jerusalem, Israel., Li M; Zhongshan School of Medicine and Key Laboratory of Tropical Diseases Control (SYSU), Sun Yat-sen University, Guangzhou, China., Lieberman J; Department of Psychiatry, Columbia University, New York, NY, USA., Light GA; Department of Psychiatry, University of California San Diego, La Jolla, CA, USA.; VISN 22, Mental Illness Research, Education and Clinical Center (MIRECC), VA San Diego Healthcare System, San Diego, CA, USA., Limborska S; Institute of Molecular Genetics of National Research Centre 'Kurchatov Institute', Moscow, Russia., Liu CM; Department of Psychiatry, National Taiwan University Hospital, Taipei, Taiwan.; Neurobiology and Cognitive Science Center, National Taiwan University, Taipei, Taiwan., Lönnqvist J; Mental Health Unit, Department of Public Health Solutions, National Institute for Health and Welfare, Helsinki, Finland.; Department of Psychiatry, University of Helsinki, Helsinki, Finland., Loughland CM; Hunter New England Health and University of Newcastle, Newcastle, New South Wales, Australia., Lubinski J; Department of Genetics and Pathology, International Hereditary Cancer Center, Pomeranian Medical University in Szczecin, Szczecin, Poland., Luykx JJ; Department of Psychiatry and Neuropsychology, School for Mental Health and Neuroscience, Maastricht University Medical Centre, Maastricht, The Netherlands.; Department of Psychiatry, UMC Utrecht Brain Center, University Medical Centre Utrecht, Utrecht University, Utrecht, The Netherlands.; Department of Translational Neuroscience, UMC Utrecht Brain Center, University Medical Center Utrecht, Utrecht University, Utrecht, The Netherlands.; Second Opinion Outpatient Clinic, GGNet Mental Health, Warnsveld, The Netherlands., Lynham A; MRC Centre for Neuropsychiatric Genetics and Genomics, Division of Psychological Medicine and Clinical Neurosciences, Cardiff University, Cardiff, UK., Macek M Jr; Department of Biology and Medical Genetics, 2nd Faculty of Medicine and University Hospital Motol, Prague, Czech Republic., Mackinnon A; Black Dog Institute, University of New South Wales, Randwick, New South Wales, Australia.; Melbourne School of Population and Global Health, University of Melbourne, Melbourne, Victoria, Australia., Magnusson PKE; Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden., Maher BS; Department of Mental Health, Bloomberg School of Public Health, Johns Hopkins University, Baltimore, MD, USA., Maier W; Department for Neurodegenerative Diseases and Geriatric Psychiatry, University Hospital Bonn, Bonn, Germany., Malaspina D; Department of Psychiatry, Icahn School of Medicine at Mount Sinai, New York, NY, USA.; Department of Genetics and Genomics, Icahn School of Medicine at Mount Sinai, New York, NY, USA., Mallet J; Asfalia Biologics, iPEPS-ICM, Hôpital Universitaire de la Pitié-Salpêtrière, Paris, France., Marder SR; Semel Institute for Neurosciene, University of California Los Angeles, Los Angeles, CA, USA., Marsal S; Rheumatology Research Group, Vall d'Hebron Research Institute, Barcelona, Spain., Martin AR; Analytic and Translational Genetics Unit, Massachusetts General Hospital, Boston, MA, USA.; Stanley Center for Psychiatric Research, Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Department of Medicine, Harvard Medical School, Boston, MA, USA., Martorell L; Hospital Universitari Institut Pere Mata, IISPV, Universitat Rovira i Virgili, CIBERSAM, Reus, Spain., Mattheisen M; Department of Biomedicine and Centre for Integrative Sequencing (iSEQ), Aarhus University, Aarhus, Denmark.; Department of Psychiatry, Dalhousie University, Halifax, Nova Scotia, Canada.; Department of Community Health and Epidemiology, Dalhousie University, Halifax, Nova Scotia, Canada.; Institute of Psychiatric Phenomics and Genomics (IPPG), University Hospital, LMU Munich, Munich, Germany., McCarley RW; VA Boston Health Care System, Brockton, MA, USA., McDonald C; Centre for Neuroimaging, Cognition and Genomics (NICOG), National University of Ireland Galway, Galway, Ireland., McGrath JJ; National Centre for Register-based Research, Aarhus University, Aarhus, Denmark.; Queensland Brain Institute, University of Queensland, Brisbane, Queensland, Australia.; Queensland Centre for Mental Health Research, The Park Centre for Mental Health, Brisbane, Queensland, Australia., Medeiros H; Department of Psychiatry and the Behavioral Sciences, Keck School of Medicine, University of Southern California, Los Angeles, CA, USA.; College of Medicine, SUNY Downstate Health Sciences University, New York, NY, USA., Meier S; Department of Psychiatry, Dalhousie University, Halifax, Nova Scotia, Canada.; Department of Biomedicine, Aarhus University, Aarhus, Denmark., Melegh B; Department of Medical Genetics, University of Pécs, School of Medicine, Pécs, Hungary., Melle I; NORMENT Centre, Division of Mental Health and Addiction, University of Oslo, Oslo, Norway.; Division of Mental Health and Addiction, Oslo University Hospital, Oslo, Norway., Mesholam-Gately RI; Department of Psychiatry, Harvard Medical School, Boston, MA, USA.; Massachusetts Mental Health Center Public Psychiatry Division of the Beth Israel Deaconess Medical Center, Boston, MA, USA., Metspalu A; Estonian Genome Center, Institute of Genomics, University of Tartu, Tartu, Estonia., Michie PT; School of Psychology, University of Newcastle, Newcastle, New South Wales, Australia., Milani L; Estonian Genome Center, Institute of Genomics, University of Tartu, Tartu, Estonia., Milanova V; Psychiatric Clinic, Alexandrovska University Hospital, Sofia, Bulgaria., Mitjans M; Clinical Neuroscience, Max Planck Institute of Experimental Medicine, Göttingen, Germany., Molden E; Department of Pharmacy, University of Oslo, Oslo, Norway.; Center for Psychopharmacology, Diakonhjemmet Hospital, Oslo, Norway., Molina E; Department of Nursing, Faculty of Health Sciences and Biomedical Research Centre (CIBM), University of Granada, Granada, Spain., Molto MD; Centro de Investigación Biomédica en Red en Salud Mental (CIBERSAM), Madrid, Spain.; Department of Genetics, Faculty of Biological Sciences, Universidad de Valencia, Valencia, Spain.; Biomedical Research Institute INCLIVA, Valencia, Spain., Mondelli V; National Institute for Health Research (NIHR) Maudsley Biomedical Research Centre at South London and Maudsley NHS Foundation Trust and King's College London, London, UK.; Department of Psychological Medicine, Institute of Psychiatry, Psychology, and Neuroscience, King's College London, London, UK., Moreno C; Centro de Investigación Biomédica en Red en Salud Mental (CIBERSAM), Madrid, Spain.; Department of Child and Adolescent Psychiatry, Institute of Psychiatry and Mental Health, General Universitario Gregorio Marañón, School of Medicine, Universidad Complutense, IiSGM, Madrid, Spain., Morley CP; Departments of Public Health and Preventive Medicine, Family Medicine, and Psychiatry and Behavioral Sciences, State University of New York, Upstate Medical University, Syracuse, NY, USA., Muntané G; Hospital Universitari Institut Pere Mata, IISPV, Universitat Rovira i Virgili, CIBERSAM, Reus, Spain.; Institut de Biologia Evolutiva (UPF-CSIC), Departament de Ciències Experimentals i de la Salut, Universitat Pompeu Fabra, PRBB, Barcelona, Spain., Murphy KC; Department of Psychiatry, Royal College of Surgeons in Ireland, Dublin, Ireland., Myin-Germeys I; Department for Neurosciences, Center for Contextual Psychiatry, KU Leuven, Leuven, Belgium., Nenadić I; Cognitive Neuropsychiatry Laboratory, Department of Psychiatry and Psychotherapy, Philipps Universität Marburg, Marburg, Germany.; Department of Psychiatry and Psychotherapy, Jena University Hospital, Jena, Germany., Nestadt G; Department of Psychiatry and Behavioral Sciences, Johns Hopkins University School of Medicine, Baltimore, MD, USA., Nikitina-Zake L; Latvian Biomedical Research and Study Centre, Riga, Latvia., Noto C; Department of Psychiatry, Universidade Federal de São Paulo, São Paulo, Brazil.; Laboratory of Integrative Neuroscience, Universidade Federal de São Paulo, São Paulo, Brazil., Nuechterlein KH; Department of Psychiatry and Biobehavioral Sciences, Geffen School of Medicine, University of California Los Angeles, Los Angeles, CA, USA., O'Brien NL; Molecular Psychiatry Laboratory, Division of Psychiatry, University College London, London, UK., O'Neill FA; Centre for Public Health, Institute of Clinical Sciences, Queen's University Belfast, Belfast, UK., Oh SY; Department of Statistics and Applied Probability, University of California at Santa Barbara, Santa Barbara, CA, USA.; Computational Research Division, Lawrence Berkeley National Laboratory, Berkeley, CA, USA., Olincy A; Department of Psychiatry, University of Colorado Denver, Aurora, CO, USA., Ota VK; Laboratory of Integrative Neuroscience, Universidade Federal de São Paulo, São Paulo, Brazil.; Department of Morphology and Genetics, Laboratorio de Genetica, Universidade Federal de São Paulo, São Paulo, Brazil., Pantelis C; NorthWestern Mental Health, Melbourne, Victoria, Australia.; Melbourne Neuropsychiatry Centre, University of Melbourne and Melbourne Health, Melbourne, Victoria, Australia.; The Florey Institute of Neuroscience and Mental Health, University of Melbourne, Parkville, Victoria, Australia.; Department of Psychiatry, Melbourne Medical School, University of Melbourne, Parkville, Victoria, Australia., Papadimitriou GN; First Department of Psychiatry, Medical School, National and Kapodistrian University of Athens, Eginition Hospital, Athens, Greece., Parellada M; Centro de Investigación Biomédica en Red en Salud Mental (CIBERSAM), Madrid, Spain.; Department of Child and Adolescent Psychiatry, Institute of Psychiatry and Mental Health, General Universitario Gregorio Marañón, School of Medicine, Universidad Complutense, IiSGM, Madrid, Spain., Paunio T; Department of Public Health Solutions, Genomics and Biomarkers Unit, National Institute for Health and Welfare, Helsinki, Finland.; Department of Psychiatry and SleepWell Research Program, Faculty of Medicine, University of Helsinki and Helsinki University Central Hospital, Helsinki, Finland., Pellegrino R; Children's Hospital of Philadelphia, Leonard Madlyn Abramson Research Center, Philadelphia, PA, USA., Periyasamy S; Queensland Brain Institute, University of Queensland, Brisbane, Queensland, Australia.; Queensland Centre for Mental Health Research, University of Queensland, Brisbane, Queensland, Australia., Perkins DO; Department of Psychiatry, University of North Carolina, Chapel Hill, NC, USA., Pfuhlmann B; Clinic of Psychiatry and Psychotherapy, Weißer Hirsch, Dresden, Germany., Pietiläinen O; Stanley Center for Psychiatric Research, Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Department of Stem Cell and Regenerative Biology, Harvard University, Cambridge, MA, USA.; Institute for Molecular Medicine Finland (FIMM), University of Helsinki, Helsinki, Finland., Pimm J; Molecular Psychiatry Laboratory, Division of Psychiatry, University College London, London, UK., Porteous D; Centre for Genomic and Experimental Medicine, Institute of Genetics and Molecular Medicine, University of Edinburgh, Western General Hospital, Edinburgh, UK., Powell J; Department of Basic and Clinical Neuroscience, Institute of Psychiatry, Psychology and Neuroscience, King's College London, London, UK., Quattrone D; Social, Genetic and Developmental Psychiatry Centre, Institute of Psychiatry, Psychology and Neuroscience, King's College London, London, UK.; National Institute for Health Research (NIHR) Maudsley Biomedical Research Centre at South London and Maudsley NHS Foundation Trust and King's College London, London, UK.; South London and Maudsley NHS Mental Health Foundation Trust, London, UK., Quested D; Oxford Health NHS Foundation Trust, Warneford Hospital, Oxford, UK.; Department of Psychiatry, University of Oxford, Oxford, UK., Radant AD; Department of Psychiatry and Behavioral Sciences, University of Washington, Seattle, WA, USA.; VA Puget Sound Health Care System, Seattle, WA, USA., Rampino A; Department of Basic Medical Science, Neuroscience and Sense Organs, University of Bari 'Aldo Moro', Bari, Italy., Rapaport MH; Huntsman Mental Health Institute, Department of Psychiatry, University of Utah School of Medicine, Salt Lake City, UT, USA., Rautanen A; Roche Pharma Research and Early Development, Pharmaceutical Sciences, Roche Innovation Center Basel, F. Hoffman-La Roche, Basel, Switzerland., Reichenberg A; Department of Psychiatry, Icahn School of Medicine at Mount Sinai, New York, NY, USA., Roe C; SUNY Upstate Medical University, Syracuse, NY, USA., Roffman JL; Department of Psychiatry, Massachusetts General Hospital, Boston, MA, USA., Roth J; Department of Psychiatry, Psychosomatics and Psychotherapy, Julius-Maximilians-Universität Würzburg, Würzburg, Germany., Rothermundt M; Department of Psychiatry, University of Münster, Münster, Germany., Rutten BPF; Department of Psychiatry and Neuropsychology, School for Mental Health and Neuroscience, Maastricht University Medical Centre, Maastricht, The Netherlands., Saker-Delye S; Généthon, Evry, France., Salomaa V; THL-Finnish Institute for Health and Welfare, Helsinki, Finland., Sanjuan J; Centro de Investigación Biomédica en Red en Salud Mental (CIBERSAM), Madrid, Spain.; Biomedical Research Institute INCLIVA, Valencia, Spain.; Department of Psychiatry, School of Medicine, University of Valencia, Hospital Clínico Universitario de Valencia, Valencia, Spain., Santoro ML; Laboratory of Integrative Neuroscience, Universidade Federal de São Paulo, São Paulo, Brazil.; Department of Morphology and Genetics, Laboratorio de Genetica, Universidade Federal de São Paulo, São Paulo, Brazil., Savitz A; Neuroscience Therapeutic Area, Janssen Research and Development, Titusville, NJ, USA., Schall U; Hunter Medical Research Institute, Newcastle, New South Wales, Australia.; Priority Centre for Brain and Mental Health Research, University of Newcastle, Mater Hospital, McAuley Centre, Newcastle, New South Wales, Australia., Scott RJ; School of Biomedical Sciences and Pharmacy, University of Newcastle, Newcastle, New South Wales, Australia.; Hunter Medical Research Institute, Newcastle, New South Wales, Australia.; Division of Molecular Medicine, NSW Health Pathology North, Newcastle, New South Wales, Australia., Seidman LJ; Department of Psychiatry, Harvard Medical School, Boston, MA, USA.; Massachusetts Mental Health Center Public Psychiatry Division of the Beth Israel Deaconess Medical Center, Boston, MA, USA., Sharp SI; Molecular Psychiatry Laboratory, Division of Psychiatry, University College London, London, UK., Shi J; Division of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, MD, USA., Siever LJ; Department of Psychiatry, Icahn School of Medicine at Mount Sinai, New York, NY, USA.; James J. Peters VA Medical Center, Bronx, NY, USA., Sigurdsson E; Faculty of Medicine, University of Iceland, Reykjavik, Iceland.; Department of Psychiatry, Landspitali University Hospital, Reykjavik, Iceland., Sim K; West Region, Institute of Mental Health, Singapore, Singapore.; Yoo Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore.; Lee Kong Chian School of Medicine, Nanyang Technological University, Singapore, Singapore., Skarabis N; Department of Psychiatry and Psychotherapy, Charité - Universitätsmedizin, Berlin, Germany., Slominsky P; Institute of Molecular Genetics of National Research Centre 'Kurchatov Institute', Moscow, Russia., So HC; School of Biomedical Sciences, The Chinese University of Hong Kong, Hong Kong, China.; Department of Psychiatry, The Chinese University of Hong Kong, Hong Kong, China., Sobell JL; Department of Psychiatry and the Behavioral Sciences, Keck School of Medicine, University of Southern California, Los Angeles, CA, USA., Söderman E; Centre for Psychiatry Research, Department of Clinical Neuroscience, Karolinska Institutet and Stockholm Health Care Services, Stockholm Region, Stockholm, Sweden., Stain HJ; School of Social and Health Sciences, Leeds Trinity University, Leeds, UK.; TIPS - Network for Clinical Research in Psychosis, Stavanger University Hospital, Stavanger, Norway., Steen NE; Division of Mental Health and Addiction, Oslo University Hospital, Oslo, Norway.; NORMENT Centre, Institute of Clinical Medicine, University of Oslo, Oslo, Norway., Steixner-Kumar AA; Clinical Neuroscience, Max Planck Institute of Experimental Medicine, Göttingen, Germany., Stögmann E; Department of Neurology, Medical University of Vienna, Vienna, Austria., Stone WS; Harvard Medical School Department of Psychiatry at Beth Israel Deaconess Medical Center, Boston, MA, USA.; Massachusetts Mental Health Center, Boston, MA, USA., Straub RE; Lieber Institute for Brain Development, Baltimore, MD, USA., Streit F; Department of Genetic Epidemiology in Psychiatry, Central Institute of Mental Health, Medical Faculty Mannheim, University of Heidelberg, Mannheim, Germany., Strengman E; Department of Medical Genetics, University Medical Centre Utrecht, Utrecht, The Netherlands., Stroup TS; Department of Psychiatry, Columbia University, New York, NY, USA., Subramaniam M; Research Division, Institute of Mental Health, Singapore, Republic of Singapore.; Saw Swee Hock School of Public Health, National University of Singapore, Singapore, Republic of Singapore., Sugar CA; Department of Psychiatry and Biobehavioral Sciences, Geffen School of Medicine, University of California Los Angeles, Los Angeles, CA, USA.; Department of Biostatistics, Fielding School of Public Health, University of California Los Angeles, Los Angeles, CA, USA., Suvisaari J; THL-Finnish Institute for Health and Welfare, Helsinki, Finland., Svrakic DM; Department of Psychiatry, Washington University, St Louis, MO, USA., Swerdlow NR; Department of Psychiatry, University of California San Diego, La Jolla, CA, USA., Szatkiewicz JP; Department of Genetics, University of North Carolina, Chapel Hill, NC, USA., Ta TMT; Department of Psychiatry, Charité - Universitätsmedizin Berlin, Berlin, Germany.; Berlin Institute of Health (BIH), Berlin, Germany., Takahashi A; Laboratory for Statistical and Translational Genetics, RIKEN Center for Integrative Medical Sciences, Yokohama, Japan., Terao C; Laboratory for Statistical and Translational Genetics, RIKEN Center for Integrative Medical Sciences, Yokohama, Japan., Thibaut F; Université de Paris, Faculté de Médecine, Hôpital Cochin-Tarnier, Paris, France.; INSERM U1266, Institut de Psychiatrie et de Neurosciences, Paris, France., Toncheva D; Department of Medical Genetics, Medical University, Sofia, Bulgaria.; Bulgarian Academy of Science, Sofia, Bulgaria., Tooney PA; School of Biomedical Sciences and Pharmacy, University of Newcastle, Newcastle, New South Wales, Australia.; Hunter Medical Research Institute, Newcastle, New South Wales, Australia.; Centre for Brain and Mental Health Research, University of Newcastle, Newcastle, New South Wales, Australia., Torretta S; Department of Basic Medical Science, Neuroscience and Sense Organs, University of Bari 'Aldo Moro', Bari, Italy., Tosato S; Department of Neuroscience, Biomedicine and Movement Sciences, Section of Psychiatry, University of Verona, Verona, Italy., Tura GB; Psychiatry Unit, IRCCS Istituto Centro San Giovanni di Dio Fatebenefratelli, Brescia, Italy., Turetsky BI; Department of Psychiatry, University of Pennsylvania, Philadelphia, PA, USA., Üçok A; Department of Psychiatry, Faculty of Medicine, Istanbul University, Istanbul, Turkey., Vaaler A; Division of Mental Health, St. Olav's Hospital, Trondheim University Hospital, Trondheim, Norway.; Department of Mental Health, Norwegian University of Science and Technology, Trondheim, Norway., van Amelsvoort T; National Institute for Health Research (NIHR) Maudsley Biomedical Research Centre at South London and Maudsley NHS Foundation Trust and King's College London, London, UK.; Department of Psychiatry and Neuropsychology, School for Mental Health and Neuroscience, Maastricht University Medical Centre, Maastricht, The Netherlands., van Winkel R; Department of Psychiatry and Neuropsychology, School for Mental Health and Neuroscience, Maastricht University Medical Centre, Maastricht, The Netherlands.; Department of Neurosciences, Center for Clinical Psychiatry, KU Leuven, Leuven, Belgium., Veijola J; Department of Psychiatry, Research Unit of Clinical Neuroscience, University of Oulu, Oulu, Finland.; Medical Research Center Oulu, Oulu University Hospital and University of Oulu, Oulu, Finland., Waddington J; Molecular and Cellular Therapeutics, Royal College of Surgeons in Ireland, Dublin, Ireland., Walter H; Department of Psychiatry and Psychotherapy, Charité - Universitätsmedizin, Berlin, Germany., Waterreus A; Neuropsychiatric Epidemiology Research Unit, School of Population and Global Health, University of Western Australia, Perth, Western Australia, Australia.; Centre for Clinical Research in Neuropsychiatry, University of Western Australia, Perth, Western Australia, Australia., Webb BT; Virginia Institute for Psychiatric and Behavioral Genetics, Department of Psychiatry, Virginia Commonwealth University, Richmond, VA, USA., Weiser M; Sheba Medical Center, Tel Hashomer, Israel., Williams NM; MRC Centre for Neuropsychiatric Genetics and Genomics, Division of Psychological Medicine and Clinical Neurosciences, Cardiff University, Cardiff, UK., Witt SH; Department of Genetic Epidemiology in Psychiatry, Central Institute of Mental Health, Medical Faculty Mannheim, University of Heidelberg, Mannheim, Germany., Wormley BK; Virginia Institute for Psychiatric and Behavioral Genetics, Department of Psychiatry, Virginia Commonwealth University, Richmond, VA, USA., Wu JQ; Baker Heart and Diabetes Institute, Melbourne, Victoria, Australia., Xu Z; Department of Psychiatry, GGz Centraal, Utrecht, The Netherlands., Yolken R; Stanley Neurovirology Laboratory, Johns Hopkins University School of Medicine, Baltimore, MD, USA., Zai CC; Campbell Family Mental Health Research Institute, Centre for Addiction and Mental Health, Toronto, Ontario, Canada.; Department of Psychiatry, University of Toronto, Toronto, Ontario, Canada., Zhou W; Bio-X Institutes, Key Laboratory for the Genetics of Developmental and Neuropsychiatric Disorders (Ministry of Education), Collaborative Innovation Center for Brain Science, Shanghai Jiao Tong University, Shanghai, China., Zhu F; Department of Psychiatry, The First Affiliated Hospital of Xi'an Jiaotong University, Xi'an, China.; Center for Translational Medicine, The First Affiliated Hospital of Xi'an Jiaotong University, Xi'an, China., Zimprich F; Department of Neurology, Medical University of Vienna, Vienna, Austria., Atbaşoğlu EC; Department of Genetics and Genomics, Icahn School of Medicine at Mount Sinai, New York, NY, USA.; Department of Psychiatry, School of Medicine, Ankara University, Ankara, Turkey., Ayub M; Department of Psychiatry, Queens University Kingston, Kingston, Ontario, Canada., Benner C; Institute for Molecular Medicine Finland (FIMM), University of Helsinki, Helsinki, Finland., Bertolino A; Department of Basic Medical Science, Neuroscience and Sense Organs, University of Bari 'Aldo Moro', Bari, Italy., Black DW; Department of Psychiatry, University of Iowa Carver College of Medicine, Iowa City, IA, USA., Bray NJ; MRC Centre for Neuropsychiatric Genetics and Genomics, Division of Psychological Medicine and Clinical Neurosciences, Cardiff University, Cardiff, UK., Breen G; Social, Genetic and Developmental Psychiatry Centre, Institute of Psychiatry, Psychology and Neuroscience, King's College London, London, UK., Buccola NG; School of Nursing, Louisiana State University Health Sciences Center, New Orleans, LA, USA., Byerley WF; Department of Psychiatry, University of California San Francisco, San Francisco, CA, USA., Chen WJ; Center for Neuropsychiatric Research, National Health Research Institutes, Zhunan Town, Taiwan.; Institute of Epidemiology and Preventive Medicine, College of Public Health, National Taiwan University, Taipei, Taiwan., Cloninger CR; Department of Psychiatry, Washington University, St Louis, MO, USA., Crespo-Facorro B; University of Sevilla, CIBERSAM IBiS, Seville, Spain.; Hospital Universitario Virgen del Rocio, Department of Psychiatry, Universidad del Sevilla, Seville, Spain., Donohoe G; Centre for Neuroimaging, Cognition and Genomics (NICOG), National University of Ireland Galway, Galway, Ireland., Freedman R; Department of Psychiatry, University of Colorado Denver, Aurora, CO, USA., Galletly C; Discipline of Psychiatry, Adelaide Medical School, University of Adelaide, Adelaide, South Australia, Australia.; Ramsay Health Care (SA) Mental Health, Adelaide, South Australia, Australia.; Northern Adelaide Local Health Network, Adelaide, South Australia, Australia., Gandal MJ; Department of Psychiatry, Semel Institute, David Geffen School of Medicine, University of California Los Angeles, Los Angeles, CA, USA., Gennarelli M; Department of Molecular and Translational Medicine, University of Brescia, Brescia, Italy.; Genetic Unit, IRCCS Istituto Centro San Giovanni di Dio Fatebenefratelli, Brescia, Italy., Hougaard DM; The Lundbeck Foundation Initiative for Integrative Psychiatric Research (iPSYCH), Aarhus, Denmark.; Center for Neonatal Screening, Department for Congenital Disorders, Statens Serum Institut, Copenhagen, Denmark., Hwu HG; Neurobiology and Cognitive Science Center, National Taiwan University, Taipei, Taiwan.; Department of Psychiatry, College of Medicine and National Taiwan University Hospital, National Taiwan University, Taipei, Taiwan., Jablensky AV; Centre for Clinical Research in Neuropsychiatry, University of Western Australia, Perth, Western Australia, Australia., McCarroll SA; Stanley Center for Psychiatric Research, Broad Institute of MIT and Harvard, Cambridge, MA, USA., Moran JL; Stanley Center for Psychiatric Research, Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Department of Psychiatry, Massachusetts General Hospital, Boston, MA, USA., Mors O; The Lundbeck Foundation Initiative for Integrative Psychiatric Research (iPSYCH), Aarhus, Denmark.; Psychosis Research Unit, Aarhus University Hospital, Aarhus, Denmark., Mortensen PB; The Lundbeck Foundation Initiative for Integrative Psychiatric Research (iPSYCH), Aarhus, Denmark.; National Centre for Register-based Research, Aarhus University, Aarhus, Denmark., Müller-Myhsok B; Max Planck Institute of Psychiatry, Munich, Germany.; Munich Cluster for Systems Neurology, Munich, Germany.; Department of Health Data Science, University of Liverpool, Liverpool, UK., Neil AL; Menzies Institute for Medical Research, University of Tasmania, Hobart, Tasmania, Australia., Nordentoft M; The Lundbeck Foundation Initiative for Integrative Psychiatric Research (iPSYCH), Aarhus, Denmark.; Mental Health Services in the Capital Region of Denmark, Mental Health Center Copenhagen, University of Copenhagen, Copenhagen, Denmark., Pato MT; Rutgers University, Robert Wood Johnson Medical School, New Brunswick, NJ, USA.; Rutgers University, New Jersey Medical School, Newark, NJ, USA., Petryshen TL; Psychiatric and Neurodevelopmental Genetics Unit, Department of Psychiatry and Center for Genomic Medicine, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA., Pirinen M; Institute for Molecular Medicine Finland (FIMM), University of Helsinki, Helsinki, Finland.; Department of Mathematics and Statistics, University of Helsinki, Helsinki, Finland.; Department of Public Health, University of Helsinki, Helsinki, Finland., Pulver AE; Department of Psychiatry and Behavioral Sciences, Johns Hopkins University School of Medicine, Baltimore, MD, USA., Schulze TG; Institute of Psychiatric Phenomics and Genomics (IPPG), University Hospital, LMU Munich, Munich, Germany.; Department of Psychiatry and Behavioral Sciences, SUNY Upstate Medical University, Syracuse, NY, USA.; Department of Psychiatry and Psychotherapy, University Medical Center Göttingen, Göttingen, Germany.; Department of Psychiatry and Behavioral Sciences, The Johns Hopkins University, Baltimore, MD, USA., Silverman JM; Department of Psychiatry, Icahn School of Medicine at Mount Sinai, New York, NY, USA.; James J. Peters VA Medical Center, Bronx, NY, USA., Smoller JW; Stanley Center for Psychiatric Research, Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Psychiatric and Neurodevelopmental Genetics Unit, Department of Psychiatry and Center for Genomic Medicine, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA., Stahl EA; Division of Psychiatric Genomics, Department of Psychiatry, Icahn School of Medicine at Mount Sinai, New York, NY, USA.; Program in Medical and Population Genetics, The Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Regeneron Genetics Center, Orange, CA, USA., Tsuang DW; Department of Psychiatry and Behavioral Sciences, University of Washington, Seattle, WA, USA.; VA Puget Sound Health Care System, Seattle, WA, USA., Vilella E; Hospital Universitari Institut Pere Mata, IISPV, Universitat Rovira i Virgili, CIBERSAM, Reus, Spain., Wang SH; College of Public Health, China Medical University, Taichung, Taiwan., Xu S; State Key Laboratory of Genetic Engineering and Ministry of Education (MOE) Key Laboratory of Contemporary Anthropology, Collaborative Innovation Center of Genetics and Development, Human Phenome Institute, School of Life Sciences, Fudan University, Shanghai, China.; School of Life Science and Technology, ShanghaiTech University, Shanghai, China.; Center for Excellence in Animal Evolution and Genetics, Chinese Academy of Sciences, Kunming, China., Adolfsson R; Department of Clinical Sciences, Psychiatry, Umeå University, Umeå, Sweden., Arango C; Centro de Investigación Biomédica en Red en Salud Mental (CIBERSAM), Madrid, Spain.; Department of Child and Adolescent Psychiatry, Institute of Psychiatry and Mental Health, General Universitario Gregorio Marañón, School of Medicine, Universidad Complutense, IiSGM, Madrid, Spain., Baune BT; Department of Psychiatry, University of Münster, Münster, Germany.; The Florey Institute of Neuroscience and Mental Health, University of Melbourne, Parkville, Victoria, Australia.; Department of Psychiatry, Melbourne Medical School, University of Melbourne, Parkville, Victoria, Australia., Belangero SI; Laboratory of Integrative Neuroscience, Universidade Federal de São Paulo, São Paulo, Brazil.; Department of Morphology and Genetics, Laboratorio de Genetica, Universidade Federal de São Paulo, São Paulo, Brazil., Børglum AD; The Lundbeck Foundation Initiative for Integrative Psychiatric Research (iPSYCH), Aarhus, Denmark.; Department of Biomedicine and Centre for Integrative Sequencing (iSEQ), Aarhus University, Aarhus, Denmark.; Center for Genomics and Personalized Medicine, Aarhus, Denmark., Braff D; Department of Psychiatry, University of California San Diego, La Jolla, CA, USA.; VISN 22, Mental Illness Research, Education and Clinical Center (MIRECC), VA San Diego Healthcare System, San Diego, CA, USA., Bramon E; Division of Psychiatry, Department of Mental Health Neuroscience, University College London, London, UK., Buxbaum JD; Department of Psychiatry, Icahn School of Medicine at Mount Sinai, New York, NY, USA., Campion D; INSERM, Rouen, France.; Centre Hospitalier du Rouvray, Rouen, France., Cervilla JA; Department of Psychiatry, San Cecilio University Hospital, University of Granada, Granada, Spain., Cichon S; Institute of Medical Genetics and Pathology, University Hospital Basel, Basel, Switzerland.; Department of Biomedicine, University of Basel, Basel, Switzerland.; Institute of Neuroscience and Medicine (INM-1), Research Center Juelich, Juelich, Germany., Collier DA; Eli Lilly and Company, Windlesham, UK., Corvin A; Neuropsychiatric Genetics Research Group, Department of Psychiatry, Trinity College Dublin, Dublin, Ireland., Curtis D; UCL Genetics Institute, University College London, London, UK.; Centre for Psychiatry, Queen Mary University London, London, UK., Forti MD; Social, Genetic and Developmental Psychiatry Centre, Institute of Psychiatry, Psychology and Neuroscience, King's College London, London, UK.; National Institute for Health Research (NIHR) Maudsley Biomedical Research Centre at South London and Maudsley NHS Foundation Trust and King's College London, London, UK.; South London and Maudsley NHS Mental Health Foundation Trust, London, UK., Domenici E; Department of Cellular, Computational and Integrative Biology, University of Trento, Trento, Italy., Ehrenreich H; Clinical Neuroscience, Max Planck Institute of Experimental Medicine, Göttingen, Germany., Escott-Price V; MRC Centre for Neuropsychiatric Genetics and Genomics, Division of Psychological Medicine and Clinical Neurosciences, Cardiff University, Cardiff, UK.; Dementia Research Institute, Cardiff University, Cardiff, UK., Esko T; Estonian Genome Center, Institute of Genomics, University of Tartu, Tartu, Estonia.; Program in Medical and Population Genetics, The Broad Institute of MIT and Harvard, Cambridge, MA, USA., Fanous AH; Department of Psychiatry, Veterans Affairs New York Harbor Healthcare System, New York, NY, USA.; Department of Psychiatry, Phoenix VA Healthcare System, Phoenix, AZ, USA.; Banner-University Medical Center, Phoenix, AZ, USA., Gareeva A; Department of Human Molecular Genetics of the Institute of Biochemistry and Genetics of the Ufa Federal Research Center of the Russian Academy of Sciences (IBG UFRC RAS), Ufa, Russia.; Federal State Educational Institution of Highest Education Bashkir State Medical University of Public Health Ministry of Russian Federation (BSMU), Ufa, Russia., Gawlik M; Department of Psychiatry, Psychosomatics and Psychotherapy, Julius-Maximilians-Universität Würzburg, Würzburg, Germany., Gejman PV; Center for Psychiatric Genetics, NorthShore University HealthSystem, Evanston, IL, USA.; Department of Psychiatry and Behavioral Neurosciences, The University of Chicago, Chicago, IL, USA., Gill M; Neuropsychiatric Genetics Research Group, Department of Psychiatry, Trinity College Dublin, Dublin, Ireland., Glatt SJ; Psychiatric Genetic Epidemiology and Neurobiology Laboratory (PsychGENe lab), Department of Psychiatry and Behavioral Sciences, SUNY Upstate Medical University, Syracuse, NY, USA., Golimbet V; Mental Health Research Center, Moscow, Russian Federation., Hong KS; Department of Psychiatry, Sungkyunkwan University School of Medicine, Samsung Medical Center, Seoul, Korea., Hultman CM; Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden., Hyman SE; Stanley Center for Psychiatric Research, Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Department of Stem Cell and Regenerative Biology, Harvard University, Cambridge, MA, USA., Iwata N; Department of Psychiatry, Fujita Health University School of Medicine, Toyoake Aichi, Japan., Jönsson EG; Centre for Psychiatry Research, Department of Clinical Neuroscience, Karolinska Institutet and Stockholm Health Care Services, Stockholm Region, Stockholm, Sweden.; NORMENT Centre, Institute of Clinical Medicine, University of Oslo, Oslo, Norway., Kahn RS; University Medical Center Utrecht, Department of Psychiatry, Rudolf Magnus Institute of Neuroscience, Utrecht, The Netherlands.; Department of Psychiatry, Icahn School of Medicine at Mount Sinai, New York, NY, USA., Kennedy JL; Campbell Family Mental Health Research Institute, Centre for Addiction and Mental Health, Toronto, Ontario, Canada.; Department of Psychiatry, University of Toronto, Toronto, Ontario, Canada., Khusnutdinova E; Department of Human Molecular Genetics of the Institute of Biochemistry and Genetics of the Ufa Federal Research Center of the Russian Academy of Sciences (IBG UFRC RAS), Ufa, Russia.; Federal State Educational Institution of Highest Education Bashkir State Medical University of Public Health Ministry of Russian Federation (BSMU), Ufa, Russia., Kirov G; MRC Centre for Neuropsychiatric Genetics and Genomics, Division of Psychological Medicine and Clinical Neurosciences, Cardiff University, Cardiff, UK., Knowles JA; Department of Psychiatry and Zilkha Neurogenetics Institute, Keck School of Medicine at University of Southern California, Los Angeles, CA, USA.; Department of Cell Biology, State University of New York, Downstate Health Sciences University, New York, NY, USA., Krebs MO; INSERM U1266, Institute of Psychiatry and Neuroscience of Paris, Université de Paris, GHU Paris Psychiatrie & Neurosciences, Paris, France., Laurent-Levinson C; Faculté de Médecine Sorbonne Université, Groupe de Recherche Clinique no. 15 - Troubles Psychiatriques et Développement (PSYDEV), Department of Child and Adolescent Psychiatry, Hôpital Universitaire de la Pitié-Salpêtrière, Paris, France.; Centre de Référence des Maladies Rares à Expression Psychiatrique, Department of Child and Adolescent Psychiatry, AP-HP Sorbonne Université, Hôpital Universitaire de la Pitié-Salpêtrière, Paris, France., Lee J; Department of Psychosis, Institute of Mental Health, Singapore, Singapore.; Neuroscience and Mental Health, Lee Kong Chian School of Medicine, Nanyang Technological University, Singapore, Singapore., Lencz T; Division of Psychiatry Research, Zucker Hillside Hospital, Glen Oaks, NY, USA.; Institute of Behavioral Science, Feinstein Institutes for Medical Research, Manhasset, NY, USA.; Department of Psychiatry, Zucker School of Medicine at Hofstra/Northwell, Hempstead, NY, USA., Levinson DF; Department of Psychiatry and Behavioral Sciences, Stanford University, Stanford, CA, USA., Li QS; Neuroscience Therapeutic Area, Janssen Research and Development, Titusville, NJ, USA., Liu J; Human Genetics, Genome Institute of Singapore, A*STAR, Singapore, Singapore.; Department of Medicine, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore., Malhotra AK; Division of Psychiatry Research, Zucker Hillside Hospital, Glen Oaks, NY, USA.; Institute of Behavioral Science, Feinstein Institutes for Medical Research, Manhasset, NY, USA.; Department of Psychiatry, Zucker School of Medicine at Hofstra/Northwell, Hempstead, NY, USA., Malhotra D; Roche Pharma Research and Early Development, Roche Innovation Center Basel, F. Hoffman-La Roche, Basel, Switzerland., McIntosh A; Division of Psychiatry, Centre for Clinical Brain Sciences, University of Edinburgh, Royal Edinburgh Hospital, Edinburgh, UK., McQuillin A; Molecular Psychiatry Laboratory, Division of Psychiatry, University College London, London, UK., Menezes PR; Department of Preventative Medicine, Faculdade de Medicina FMUSP, University of São Paulo, São Paulo, Brazil., Morgan VA; Neuropsychiatric Epidemiology Research Unit, School of Population and Global Health, University of Western Australia, Perth, Western Australia, Australia.; Centre for Clinical Research in Neuropsychiatry, University of Western Australia, Perth, Western Australia, Australia., Morris DW; Centre for Neuroimaging, Cognition and Genomics (NICOG), National University of Ireland Galway, Galway, Ireland., Mowry BJ; Queensland Brain Institute, University of Queensland, Brisbane, Queensland, Australia.; Queensland Centre for Mental Health Research, University of Queensland, Brisbane, Queensland, Australia., Murray RM; 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Publikováno v: Nature [Nature] 2022 Apr; Vol. 604 (7906), pp. 502-508. Date of Electronic Publication: 2022 Apr 08.

Partitioning heritability of regulatory and cell-type-specific variants across 11 common diseases

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Publikováno v: American journal of human genetics, 95(5), 535-552. Cell Press
American Journal of Human Genetics, 95(5), 535-52. Cell Press
Gusev, A, Lee, S H, Trynka, G, Finucane, H, Vilhjálmsson, B J, Xu, H, Zang, C, Ripke, S, Bulik-Sullivan, B, Stahl, E, Kähler, A K, Hultman, C M, Purcell, S M, McCarroll, S A, Daly, M, Pasaniuc, B, Sullivan, P F, Neale, B M, Wray, N R, Raychaudhuri, S, Price, A L & Schizophrenia Working Group of the Psychiatric Genomics Consortium (Manuel Mattheisen and Jakob Grove, members) 2014, ' Partitioning Heritability of Regulatory and Cell-Type-Specific Variants across 11 Common Diseases ', American Journal of Human Genetics, vol. 95, no. 5, pp. 535-52 . https://doi.org/10.1016/j.ajhg.2014.10.004
Gusev, A, Lee, S H, Trynka, G, Finucane, H, Vilhjálmsson, B J, Xu, H, Zang, Z, Ripke, S, Bulik-Sullivan, B K, Stahl, E, Kähler, A K, Hultman, C M, Purcell, S M, McCarroll, S A, Daly, M, Pasaniuc, B, Sullivan, P F, Neale, B M, Wray, N R, Raychaudhuri, S & Price, A L 2014, ' Partitioning heritability of regulatory and cell-type-specific variants across 11 common diseases. ', American Journal of Human Genetics, vol. 95, no. 5, pp. 535-552 . https://doi.org/10.1016/j.ajhg.2014.10.004
The American Journal of Human Genetics
ResearcherID
American Journal of Human Genetics, 95(5), 535-552. Cell Press

Regulatory and coding variants are known to be enriched with associations identified by genome-wide association studies (GWASs) of complex disease, but their contributions to trait heritability are currently unknown. We applied variance-component met

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e29bdf4204020af869d2d95c2fb75871
https://cris.maastrichtuniversity.nl/en/publications/75c3ad86-f8fe-4e39-8084-1e7684a19e86

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Autor: Calabrò M; Department of Biomedical and Dental Sciences and Morphofunctional Imaging, University of Messina, Messina, Italy., Mandelli L; Department of Biomedical and NeuroMotor Sciences, University of Bologna, Viale Carlo Pepoli 5, 40123, Bologna, Italy., Crisafulli C; Department of Biomedical and Dental Sciences and Morphofunctional Imaging, University of Messina, Messina, Italy., Porcelli S; Department of Biomedical and NeuroMotor Sciences, University of Bologna, Viale Carlo Pepoli 5, 40123, Bologna, Italy., Albani D; Laboratory of Biology of Neurodegenerative Disorders, Neuroscience Department, Istituto di Ricerche Farmacologiche Mario Negri IRCSS, Milan, Italy., Politis A; Department of Psychiatry, University of Athens Medical School, Eginition Hospital, Athens, Greece., Papadimitriou GN; Department of Psychiatry, University of Athens Medical School, Eginition Hospital, Athens, Greece., Di Nicola M; Fondazione Policlinico Universitario 'A. Gemelli' - IRCCS, Università Cattolica del Sacro Cuore, Rome, Italy., Janiri L; Fondazione Policlinico Universitario 'A. Gemelli' - IRCCS, Università Cattolica del Sacro Cuore, Rome, Italy., Colombo R; Fondazione Policlinico Universitario 'A. Gemelli' - IRCCS, Università Cattolica del Sacro Cuore, Rome, Italy., Martinotti G; Department of Neuroscience, Imaging and Clinical Sciences, University 'G. d'Annunzio' of Chieti, Chieti, Italy., Bellomo A; Psychiatry Unit, Department of Medical Sciences, University of Foggia, Foggia, Italy., Vieta E; Bipolar Disorders Unit, Institute of Neuroscience, Hospital Clínic, University of Barcelona, IDIBAPS, CIBERSAM, Barcelona, Catalonia, Spain., Bonassi S; Unit of Clinical and Molecular Epidemiology, IRCCS San Raffaele Pisana, Rome, Italy, and Department of Human Sciences and Quality of Life Promotion, San Raffaele University, Rome, Italy., Frustaci A; Barnet, Enfield and Haringey Mental Health NHS Trust, St.Ann's Hospital, St.Ann's Road, London, N15 3 TH, UK., Ducci G; Mental Health Department, ASL Roma 1, Rome, Italy., Landi S; Dipartimento di Biologia, Università di Pisa, Pisa, Italy., Boccia S; Section of Hygiene, Institute of Public Health, Universita' Cattolica del Sacro Cuore, Fondazione Policlinico 'Agostino Gemelli' IRCCS, Rome, Italy., Serretti A; Department of Biomedical and NeuroMotor Sciences, University of Bologna, Viale Carlo Pepoli 5, 40123, Bologna, Italy. alessandro.serretti@unibo.it.

Publikováno v: Molecular biology reports [Mol Biol Rep] 2020 Jan; Vol. 47 (1), pp. 191-200. Date of Electronic Publication: 2019 Oct 08.