Zobrazeno 1 - 10
of 556
pro vyhledávání: '"Paolo de Coppi"'
Autor:
Savvas Savvidis, Roberta Ragazzini, Valeria Conde de Rafael, J. Ciaran Hutchinson, Lorenzo Massimi, Fabio A. Vittoria, Sara Campinoti, Tom Partridge, Olumide K. Ogunbiyi, Alessia Atzeni, Neil J. Sebire, Paolo De Coppi, Alberto Mittone, Alberto Bravin, Paola Bonfanti, Alessandro Olivo
Publikováno v:
Communications Medicine, Vol 4, Iss 1, Pp 1-12 (2024)
Abstract Background The thymus, responsible for T cell-mediated adaptive immune system, has a structural and functional complexity that is not yet fully understood. Until now, thymic anatomy has been studied using histological thin sections or confoc
Externí odkaz:
https://doaj.org/article/46d78d1b44754c699d1b650dc9f7fdd6
Autor:
Alexandra Stewart, Roganie Govender, Simon Eaton, Christina H. Smith, Paolo De Coppi, Jo Wray
Publikováno v:
Orphanet Journal of Rare Diseases, Vol 19, Iss 1, Pp 1-15 (2024)
Abstract Introduction Eating, drinking and swallowing difficulties are commonly reported morbidities for individuals born with OA/TOF. This study aimed to determine the nature and prevalence of eating, drinking and oro-pharyngeal swallowing difficult
Externí odkaz:
https://doaj.org/article/9429cc7640f742ad974793ec3878b3b1
Publikováno v:
Journal of Pediatric Surgery Open, Vol 4, Iss , Pp 100092- (2023)
Background: Congenital duodenal obstruction occur with other anomalies in 50% of cases. Although predictable, its association with biliary/pancreatic anomalies is rarely reported. All cases of duodenal atresia (DA) and stenosis (DS) associated with b
Externí odkaz:
https://doaj.org/article/e02646fe2d6d490fa5e9e23fa246b677
Hydrogel-in-hydrogel live bioprinting for guidance and control of organoids and organotypic cultures
Autor:
Anna Urciuolo, Giovanni Giuseppe Giobbe, Yixiao Dong, Federica Michielin, Luca Brandolino, Michael Magnussen, Onelia Gagliano, Giulia Selmin, Valentina Scattolini, Paolo Raffa, Paola Caccin, Soichi Shibuya, Dominic Scaglioni, Xuechun Wang, Ju Qu, Marko Nikolic, Marco Montagner, Gabriel L. Galea, Hans Clevers, Monica Giomo, Paolo De Coppi, Nicola Elvassore
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-14 (2023)
Abstract Three-dimensional hydrogel-based organ-like cultures can be applied to study development, regeneration, and disease in vitro. However, the control of engineered hydrogel composition, mechanical properties and geometrical constraints tends to
Externí odkaz:
https://doaj.org/article/8d949ed909e143ba8263b25ad3233dc1
Autor:
M. Guftar Shaikh, Angela K. Lucas-Herald, Antonia Dastamani, Maria Salomon Estebanez, Senthil Senniappan, Noina Abid, Sumera Ahmad, Sophie Alexander, Bindu Avatapalle, Neelam Awan, Hester Blair, Roisin Boyle, Alexander Chesover, Barbara Cochrane, Ross Craigie, Annaruby Cunjamalay, Sarah Dearman, Paolo De Coppi, Karen Erlandson-Parry, Sarah E. Flanagan, Clare Gilbert, Niamh Gilligan, Caroline Hall, Jayne Houghton, Ritika Kapoor, Helen McDevitt, Zainab Mohamed, Kate Morgan, Jacqueline Nicholson, Ana Nikiforovski, Elaine O'Shea, Pratik Shah, Kirsty Wilson, Chris Worth, Sarah Worthington, Indraneel Banerjee
Publikováno v:
Frontiers in Endocrinology, Vol 14 (2023)
Congenital hyperinsulinism (CHI) is a condition characterised by severe and recurrent hypoglycaemia in infants and young children caused by inappropriate insulin over-secretion. CHI is of heterogeneous aetiology with a significant genetic component a
Externí odkaz:
https://doaj.org/article/6ae549a70f2e4683982d8ee5ac0a6878
Publikováno v:
Frontiers in Chemical Engineering, Vol 5 (2023)
Lung organoids have emerged as powerful tools for studying lung distal diseases by recapitulating the cellular diversity and microenvironment of the lung tissue. This review article highlights the advancements in leveraging mechanobiology and biophys
Externí odkaz:
https://doaj.org/article/2f4ade9450904e9eb7748889bbfcca4a
Publikováno v:
Frontiers in Chemical Engineering, Vol 5 (2023)
Gastrointestinal organ failure, from congenital or postnatally acquired pathologies, is a major cause of death across countries of all income levels. Organoids and engineered tissues have been widely investigated as tools to model organ functions and
Externí odkaz:
https://doaj.org/article/d0f685c53f014a89bf8f254f4e9e47f1
Autor:
Giuseppe Calà, Beatrice Sina, Paolo De Coppi, Giovanni Giuseppe Giobbe, Mattia Francesco Maria Gerli
Publikováno v:
Frontiers in Bioengineering and Biotechnology, Vol 11 (2023)
During the past 10 years the world has experienced enormous progress in the organoids field. Human organoids have shown huge potential to study organ development, homeostasis and to model diseases in vitro. The organoid technology has been widely and
Externí odkaz:
https://doaj.org/article/22956992a6c248b39b863d674e93224e
Autor:
Edoardo Maghin, Eugenia Carraro, Daniele Boso, Arben Dedja, Mattia Giagante, Paola Caccin, Raluca Ana-Maria Barna, Silvia Bresolin, Alice Cani, Giulia Borile, Deborah Sandrin, Filippo Romanato, Francesca Cecchinato, Anna Urciuolo, Dorianna Sandonà, Paolo De Coppi, Piero G. Pavan, Martina Piccoli
Publikováno v:
npj Regenerative Medicine, Vol 7, Iss 1, Pp 1-15 (2022)
Abstract The production of skeletal muscle constructs useful for replacing large defects in vivo, such as in congenital diaphragmatic hernia (CDH), is still considered a challenge. The standard application of prosthetic material presents major limita
Externí odkaz:
https://doaj.org/article/1bbd983d9cd5431fa103f3f36913e3b0
Autor:
Giovanni Giuseppe Giobbe, Francesco Bonfante, Brendan C. Jones, Onelia Gagliano, Camilla Luni, Elisa Zambaiti, Silvia Perin, Cecilia Laterza, Georg Busslinger, Hannah Stuart, Matteo Pagliari, Alessio Bortolami, Eva Mazzetto, Anna Manfredi, Chiara Colantuono, Lucio Di Filippo, Alessandro Filippo Pellegata, Valentina Panzarin, Nikhil Thapar, Vivian Sze Wing Li, Simon Eaton, Davide Cacchiarelli, Hans Clevers, Nicola Elvassore, Paolo De Coppi
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-14 (2021)
Several clinical reports have described gastrointestinal symptoms for COVID-19, though whether the virus can replicate within the stomach remains unclear. Here the authors generate gastric organoids from human biopsies and show that the virus can eff
Externí odkaz:
https://doaj.org/article/16f8748d432646d085ed25fa4b80e5ce