Zobrazeno 1 - 10
of 126
pro vyhledávání: '"Paolo d'Amico"'
Autor:
Lorenzo Gerratana, Andrew A. Davis, Marko Velimirovic, Katherine Clifton, Whitney L. Hensing, Ami N. Shah, Charles S. Dai, Carolina Reduzzi, Paolo D’Amico, Firas Wehbe, Arielle Medford, Seth A. Wander, William J. Gradishar, Amir Behdad, Fabio Puglisi, Cynthia X. Ma, Aditya Bardia, Massimo Cristofanilli
Publikováno v:
Breast Cancer Research, Vol 25, Iss 1, Pp 1-12 (2023)
Abstract Background although being central for the biology and druggability of hormone-receptor positive, HER2 negative metastatic breast cancer (MBC), ESR1 and PIK3CA mutations are simplistically dichotomized as mutated or wild type in current clini
Externí odkaz:
https://doaj.org/article/e709c732d873422f9a1a421cdc570023
Autor:
Andrew A. Davis, Lorenzo Gerratana, Katherine Clifton, Arielle J. Medford, Marko Velimirovic, Whitney L. Hensing, Leslie Bucheit, Ami N. Shah, Paolo D'Amico, Carolina Reduzzi, Qiang Zhang, Charles S. Dai, Elyssa N. Denault, Nusayba A. Bagegni, Mateusz Opyrchal, Foluso O. Ademuyiwa, Ron Bose, William J. Gradishar, Amir Behdad, Cynthia X. Ma, Aditya Bardia, Massimo Cristofanilli
Publikováno v:
EBioMedicine, Vol 86, Iss , Pp 104316- (2022)
Summary: Background: Limited data exist to characterise molecular differences in circulating tumour DNA (ctDNA) for patients with invasive lobular carcinoma (ILC). We analysed metastatic breast cancer patients with ctDNA testing to assess genomic dif
Externí odkaz:
https://doaj.org/article/07b125b3c92b42acba72a92a3f8e5d48
Autor:
Rokana Taftaf, Xia Liu, Salendra Singh, Yuzhi Jia, Nurmaa K. Dashzeveg, Andrew D. Hoffmann, Lamiaa El-Shennawy, Erika K. Ramos, Valery Adorno-Cruz, Emma J. Schuster, David Scholten, Dhwani Patel, Youbin Zhang, Andrew A. Davis, Carolina Reduzzi, Yue Cao, Paolo D’Amico, Yang Shen, Massimo Cristofanilli, William A. Muller, Vinay Varadan, Huiping Liu
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-15 (2021)
Circulating tumor cell (CTC) clusters are more efficient at mediating metastasis as compared to single cells and are associated with poor prognosis in breast cancer. Here, the authors show that ICAM1 is enriched in CTC clusters and its loss suppresse
Externí odkaz:
https://doaj.org/article/017f7ea6455b4bbfa2e1554f4c8f4748
Autor:
Carolina REDUZZI, Lorenzo Gerratana, Youbin Zhang, Maroua MANAI, Paolo D’Amico, Andrew A. Davis, Jeannine Donahue, Ami N. Shah, Massimo Cristofanilli
Publikováno v:
Cancer Research. 83:P2-26
Background: Circulating tumor cells (CTCs) in breast cancer (BC) are commonly defined as epithelial cells (EPCAM and cytokeratin (CK) positive), lacking the universal blood cell marker CD45. Nonetheless, CTCs expressing both CK and CD45 (= dual-posit
Autor:
Giuseppe Emmanuele Umana, Nicola Alberio, Paolo Amico, Anna Maria Lavecchia, Saverio Fagone, Marco Fricia, Giovanni Nicoletti, Salvatore Cicero, Gianluca Scalia
Publikováno v:
Interdisciplinary Neurosurgery, Vol 20, Iss , Pp - (2020)
Background: Ovarian brain metastases represent a very rare occurrence and without treatment, prognosis is very poor, with a median survival of one month. We present a unique case of a patient affected by a giant cystic intracerebral metastasis (>7 cm
Externí odkaz:
https://doaj.org/article/dab1f6cc529a4711945d47677c04405f
Autor:
Lorenzo Gerratana, Andrew A. Davis, Marko Velimirovic, Carolina Reduzzi, Katherine Clifton, Leslie Bucheit, Whitney L. Hensing, Ami N. Shah, Tania Pivetta, Charles S. Dai, Paolo D'Amico, Firas Wehbe, Arielle Medford, Seth A. Wander, William J. Gradishar, Amir Behdad, Cynthia X. Ma, Fabio Puglisi, Aditya Bardia, Massimo Cristofanilli
Publikováno v:
JCO Precision Oncology.
PURPOSE As the continuation beyond progression (BP) of cyclin-dependent kinase 4/6 inhibitors (CDK4/6i) is becoming increasingly attractive for the treatment of patients with hormone receptor (HR)–positive, human epidermal growth factor receptor 2
Autor:
Mandara M. Harikar, Gianluca Ferini, Paolo Palmisciano, Muhammad Shakir, Paolo Amico, Stefano Ferraresi, Giuseppe E. Umana
Publikováno v:
Frontiers in Oncology. 13
IntroductionMalignant peripheral nerve sheath tumors (MPNSTs) are a group of rare soft tissue sarcomas of mesenchymal origin. These tumors generally require extensive local excision owing to their aggressive potential. Though the role of radiotherapy
Autor:
MATIAS BALDONCINI, GIANLUCA FERINI, GIUSEPPE E. UMANA, BIPIN CHAURASIA, MICKAELA ECHAVARRIA DEMICHELIS, JUAN F. VILLALONGA, PAOLO PALMISCIANO, PAOLO AMICO, SABINO LUZZI, DEREK O. PIPOLO, ALVARO CAMPERO
Publikováno v:
Anticancer Research. 42:3203-3207
Extraventricular supratentorial ependymomas are rare entities. Most ependymomas are located at the infratentorial and intraventricular level, and only in a small group of cases they do not present continuity with the ventricular system. This is a cas
Autor:
Massimo Cristofanilli, Paolo D'Amico
Publikováno v:
JCO Oncology Practice. 18:331-334
Autor:
Bruno A Duso, Elena Gavilán Dorronzoro, Giulia Tini, Maria R de Filippo, Emanuele Bonetti, Maria R Ippolito, Chiara Soriani, Paolo D'Amico, Simona Rodighiero, Giuseppe Curigliano, Stefano Santaguida, Massimo Cristofanilli, Pier Giuseppe Pelicci, Luca Mazzarella
Publikováno v:
Cancer Research. 82:P5-13
Background: Despite major technological and conceptual advancements, treatment decisions in HER2+ metastatic breast cancer (mBC) remain largely based on clinical evidence, with no established predictive biomarkers to direct treatment for individual p