Zobrazeno 1 - 10
of 144
pro vyhledávání: '"Paolo Ubezio"'
Autor:
Marco Giordano, Alessandra Decio, Chiara Battistini, Micol Baronio, Fabrizio Bianchi, Alessandra Villa, Giovanni Bertalot, Stefano Freddi, Michela Lupia, Maria Giovanna Jodice, Paolo Ubezio, Nicoletta Colombo, Raffaella Giavazzi, Ugo Cavallaro
Publikováno v:
Journal of Experimental & Clinical Cancer Research, Vol 40, Iss 1, Pp 1-19 (2021)
Abstract Background Cancer stem cells (CSC) have been implicated in tumor progression. In ovarian carcinoma (OC), CSC drive tumor formation, dissemination and recurrence, as well as drug resistance, thus contributing to the high death-to-incidence ra
Externí odkaz:
https://doaj.org/article/ad85c4ef74d047668cf54b3776191384
Autor:
Lavinia Morosi, Marina Meroni, Paolo Ubezio, Ilaria Fuso Nerini, Lucia Minoli, Luca Porcu, Nicolò Panini, Marika Colombo, Barbara Blouw, David W. Kang, Enrico Davoli, Massimo Zucchetti, Maurizio D’Incalci, Roberta Frapolli
Publikováno v:
Journal of Experimental & Clinical Cancer Research, Vol 40, Iss 1, Pp 1-13 (2021)
Abstract Background Scarce drug penetration in solid tumours is one of the possible causes of the limited efficacy of chemotherapy and is related to the altered tumour microenvironment. The abnormal tumour extracellular matrix (ECM) together with abn
Externí odkaz:
https://doaj.org/article/4214b5ab153e4739bc53c7865dca3750
Autor:
Federica Portale, Giulia Cricrì, Silvia Bresolin, Monica Lupi, Stefania Gaspari, Daniela Silvestri, Barbara Russo, Noemi Marino, Paolo Ubezio, Fabio Pagni, Patrizia Vergani, Geertruy Te Kronnie, Maria Grazia Valsecchi, Franco Locatelli, Carmelo Rizzari, Andrea Biondi, Erica Dander, Giovanna D’Amico
Publikováno v:
Haematologica, Vol 104, Iss 3 (2019)
B-cell precursor-acute lymphoblastic leukemia modulates the bone marrow (BM) niche to become leukemia-supporting and chemo-protective by reprogramming the stromal microenvironment. New therapies targeting the interplay between leukemia and stroma can
Externí odkaz:
https://doaj.org/article/53356333dc434c4685139612b426ac39
Autor:
Katiuscia Bonezzi, Dorina Belotti, Brian J. North, Carmen Ghilardi, Patrizia Borsotti, Andrea Resovi, Paolo Ubezio, Antonella Riva, Raffaella Giavazzi, Eric Verdin, Giulia Taraboletti
Publikováno v:
Neoplasia: An International Journal for Oncology Research, Vol 14, Iss 9, Pp 846-854 (2012)
Taxanes are potent inhibitors of cell motility, a property implicated in their antiangiogenic and antimetastatic activity and unrelated to their antiproliferative effect. The molecular mechanism of this anti-motility activity is poorly understood. In
Externí odkaz:
https://doaj.org/article/324bba01ddad45f9bda06f2d628005cb
Publikováno v:
PLoS Computational Biology, Vol 9, Iss 10, p e1003293 (2013)
The antiproliferative response to anticancer treatment is the result of concurrent responses in all cell cycle phases, extending over several cell generations, whose complexity is not captured by current methods. In the proposed experimental/computat
Externí odkaz:
https://doaj.org/article/46a8065e03ef4c0fba78f30d004bfa46
Autor:
Luca Porcu, Angela Recchia, Cristina Bosetti, Maria Vittoria Chiaruttini, Sara Uggeri, Giada Lonati, Paolo Ubezio, Barbara Rizzi, Oscar Corli
Purpose Various prognostic indexes have been proposed to improve physicians’ ability to predict survival time in advanced cancer patients admitted to palliative care (PC), but no optimal score has still been identified. The study therefore aims to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ebc6b45eafc58eea22b09085a79444cb
https://doi.org/10.21203/rs.3.rs-2869187/v1
https://doi.org/10.21203/rs.3.rs-2869187/v1
Autor:
Maurizio D'Incalci, Silvana Pilotti, Alessandro Gronchi, Paolo Giovanni Casali, Roberta Sanfilippo, Silvia Brich, Luca Porcu, Paolo Ubezio, Laura Carrassa, Sergio Marchini, Sara Ballabio, Laura Mannarino, Ilaria Craparotta, Marianna Ponzo, Ezia Bello, Roberta Frapolli
Immunohistochemistry with anti-CD-31 antibody
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::86b4243e96fcf000144b93d6cbdde108
https://doi.org/10.1158/1078-0432.22472168.v1
https://doi.org/10.1158/1078-0432.22472168.v1
Autor:
Maurizio D'Incalci, Silvana Pilotti, Alessandro Gronchi, Paolo Giovanni Casali, Roberta Sanfilippo, Silvia Brich, Luca Porcu, Paolo Ubezio, Laura Carrassa, Sergio Marchini, Sara Ballabio, Laura Mannarino, Ilaria Craparotta, Marianna Ponzo, Ezia Bello, Roberta Frapolli
Purpose:This study was aimed at investigating whether the PPARγ agonist pioglitazone—given in combination with trabectedin—is able to reactivate adipocytic differentiation in myxoid liposarcoma (MLS) patient-derived xenografts, overcoming resist
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a9b6dd86019a596f348e8a0f6689e220
https://doi.org/10.1158/1078-0432.c.6528143.v1
https://doi.org/10.1158/1078-0432.c.6528143.v1
Autor:
Paolo Ubezio, Raffaella Giavazzi, Maria Rosa Bani, Elisa D'Agostini, Francesca Bizzaro, Francesca Falcetta
Comparison of the tumor growth curves of single-drug PTX and two-drugs DDP/PTX treatments with the expected curve for the DDP/PTX combination
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d1cef24fffbd1605d97c0f1b04e7eb3d
https://doi.org/10.1158/0008-5472.22414712
https://doi.org/10.1158/0008-5472.22414712
Autor:
Paolo Ubezio, Raffaella Giavazzi, Maria Rosa Bani, Elisa D'Agostini, Francesca Bizzaro, Francesca Falcetta
The margin for optimizing polychemotherapy is wide, but a quantitative comparison of current and new protocols is rare even in preclinical settings. In silico reconstruction of the proliferation process and the main perturbations induced by treatment
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::78d1b1c087a10de3b0bb49e64f57b596
https://doi.org/10.1158/0008-5472.c.6509057.v1
https://doi.org/10.1158/0008-5472.c.6509057.v1