Výsledky vyhledávání - "Paolo Rodighiero"

Synthesis and biological activity of linear and angular 4-methoxymethylthienocoumarins and 4-acetoxymethylthienocoumarins

Autor: Paolo Rodighiero, Giovanni Pastorini, Lisa Dalla Via, Ornella Gia, Sebastiano Marciani Magno

Publikováno v: Il Farmaco. 53:313-319

This paper reports the synthesis of 4-methoxymethyl and 4-acetoxymethyl-6,9-dimethyl-2 H -thieno[3,2-g]-1-benzopyran-2-one as well as 4-methoxymethyl- and 4-acetoxymethyl-6,9-dimethyl-2 H -thieno[2,3-h]-1-benzopyran-2-one. The synthesized derivatives

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b5f0af1e96b27d2210556aefdc027b22
https://doi.org/10.1016/s0014-827x(98)00007-x

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Difurocoumarins, Psoralen Analogs: Synthesis and DNA Photobinding

Autor: Francesco Dall'Acqua, Paolo Rodighiero, Anne C. E. Moor, Sergio Caffieri, Adriano Guiotto, Gerard M. J. Beijersbergen van Henegouwen, Adriana Chilin

Publikováno v: Zeitschrift für Naturforschung B. 50:1257-1264

A new tetracyclic derivative, difurocoumarin, was synthesized and studied in order to ascertain its possible use as a photochemotherapeutic agent alternative to psoralens. The compound proved able to photobind monofunctionally to DNA on irradiation w

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::22e34bb27ae626ff73111cf1fa3964be
https://doi.org/10.1515/znb-1995-0821

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DNA damage and topoisomerase II inhibition induced by a benzopsoralen derivative

Autor: B. Pani, Francarosa Baccichetti, Paolo Rodighiero, Elio Russo, Franco Bordin, Christine Marzano, Barbisin M, F. Carlassare, M. Tamaro

Publikováno v: Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis. 311:277-285

The ability of 4-hydroxymethyl-4',5'-benzopsoralen (HMBP) to damage DNA of Chinese hamster ovary cells (CHO) and to inhibit the activity of topoisomerase II in vitro has been studied. This compound is characterized by a fourth ring condensed at the f

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d97155c25113a8af5e79caf4cc8b2778
https://doi.org/10.1016/0027-5107(94)90186-4

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4,6,4′-Trimethylangelicin induces interstrand cross-links in mammalian cell DNA

Autor: Paolo Rodighiero, C. Gatto, Francarosa Baccichetti, Christine Marzano, F. Carlassare, Franco Bordin

Publikováno v: Journal of Photochemistry and Photobiology B: Biology. 26:197-201

4,6,4′-Trimethylangelicin, a well-known effective photosensitizer described as a pure monofunctional reactant with DNA, can induce interstrand cross-links in mammalian cell DNA in vivo (about 15% relative to 8-methoxypsoralen), as observed using al

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d0a12e6152753e9030ffd26001f0e6b7
https://doi.org/10.1016/1011-1344(94)07040-7

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2,6-Dimethyl-9-methoxy-4H-pyrrolo [3,2,1-ij]quinolin-4-one, a new compound with unusual photosensitizing properties

Autor: Francarosa Baccichetti, Christine Marzano, Franco Bordin, Adriana Chilin, Paolo Rodighiero, F. Carlassare, Andrea Guiotto

Publikováno v: Journal of Photochemistry and Photobiology B: Biology. 24:101-108

Some photobiological properties of 2,6-dimethyl-9-methoxy-4H-pyrrolo [3,2,1-ij]quinolin-4-one (PQ) have been studied in comparison with 8-methoxypsoralen (8-MOP). In Ehrlich cells, PQ induced a moderate inhibition in DNA and RNA syntheses in the dark

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::32e45fd8179ccdcf87221b46ba33bd1e
https://doi.org/10.1016/1011-1344(94)07011-3

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Synthesis of methyl derivatives of new polycyclic systems of 4H-furo[3,2-g]pyrrolo[3,2,1-ij]quinolin-4-one, of 1H,5H- and 3H,5H-benzofuro[5,6,7-ij]quinolizin-5-one

Autor: P. Manzini, Giuliano Bandoli, Paolo Rodighiero, Adriana Chilin, A. Guiotto

Publikováno v: Journal of Heterocyclic Chemistry. 30:715-722

The synthesis of new tetracyclic 4H-furo[3,2-g]pyrrolo[3,2,1-ij]quinolin-4-ones, 15–17, 1H,5H-benzofuro[5,6, 7-ij]quinolizin-5-ones, 18–20, and 3H,5H-benzofuro[5,6,7-ij]quinolizin-5-ones, 21–23 is described. The planarity of the structure of be

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::106f9e0ab9684bfc0ca90fe1387faa31
https://doi.org/10.1002/jhet.5570300322

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ChemInform Abstract: Synthesis of Methyl Derivatives of New Polycyclic Systems of 4H-Furo(3, 2-g)pyrrolo(3,2,1-ij)quinolin-4-one, of 1H,5H- and 3H,5H-Benzofuro(5,6, 7-ij)quinolizin-5-one

Autor: Paolo Rodighiero, Giuliano Bandoli, Adriana Chilin, P. Manzini, A. Guiotto

Publikováno v: ChemInform. 24

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::d1c9ff66c25285a6537975e00e2f74fe
https://doi.org/10.1002/chin.199349201

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