Výsledky vyhledávání - "Paolo Pessina"

The Effects of Hypoxia/Reoxygenation on the Physiological Behaviour of U373-Mg Astrocytes

Autor: Gian Paolo Pessina, Paola De Rosa, Silvia Leoncini, Silvia Maria Maiorca, Lucia Ciccoli, Carlo Aldinucci, Claudia Sticozzi, Mitri Palmi, Cinzia Signorini

Publikováno v: Neurochemical Research. 35:42-49

Nerve cells are very susceptible to hypoxia responsive for mitochondrial dysfunctions involved in the subsequent oxidative stress, apoptosis and necrosis. In this paper, we examined the effect of 12 h incubation of U-373 MG astrocytes in hypoxic envi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c5ccf1bc549a3a7eff67158b1e83251f
https://doi.org/10.1007/s11064-009-0028-3

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Potentiation of intracellular Ca2+mobilization by hypoxia-induced NO generation in rat brain striatal slices and human astrocytoma U-373 MG cells and its involvement in tissue damage

Autor: Carlo Aldinucci, Alberto Benocci, Mitri Palmi, Gian Pietro Sgaragli, Julian Blanco Garcia, Antonella Meini, Gian Paolo Pessina, Maria Frosini

Publikováno v: European Journal of Neuroscience. 17:692-700

The relationship between nitric oxide (NO) and intracellular Ca 2 + in hypoxic-ischemic brain damage is not known in detail. Here we used rat striatal slices perfused under low-oxygen and Ca 2 + -free conditions and cultured human astrocytoma cells i

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::539714caacc42d08216c97239de73baa
https://doi.org/10.1046/j.1460-9568.2003.02483.x

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Pharmacokinetics and catabolism of tumor necrosis factor-α in rat lungs

Autor: E. Luzzi, Michela Tanzini, Velio Bocci, Luana Paulesu, F. Corradeschi, Carlo Aldinucci, Gian Paolo Pessina

Publikováno v: Immunopharmacology. 29:245-250

The role of the lungs in the catabolism of tumor necrosis factor alpha (TNF-alpha) either in normal rats, or in rats subjected to an acute cigarette smoking episode has been evaluated by using isolated and perfused lung preparations. After administra

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7653af178964296f8048e8702519cfbf
https://doi.org/10.1016/0162-3109(95)00064-z

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The physiological behaviour of IMR-32 neuroblastoma cells is affected by a 12-h hypoxia/24-h reoxygenation period

Autor: Silvia Leoncini, Lucia Ciccoli, Silvia Maria Maiorca, Carlo Aldinucci, Giuseppe Valacchi, Paola De Rosa, Gian Paolo Pessina, Mitri Palmi, Cinzia Signorini, Claudia Sticozzi

Nervous system cells are highly dependent on adequate tissue oxygenation and are very susceptible to hypoxia, which causes mitochondrial dysfunctions involved in apoptosis and necrosis. In this paper, we examine the effect of a 12-h incubation of dif

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b94d4590e38f3b081e7f2f053eb5bb59
http://hdl.handle.net/11365/19200

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Hypoxia affects the physiological behaviour of rat cortical synaptosomes

Autor: Giuseppe Buonocore, Silvia Leoncini, Alessandra Carretta, Cinzia Signorini, Gian Paolo Pessina, Carlo Aldinucci, Lucia Ciccoli

Nerve cells, especially synaptosomes, are very susceptible to hypoxia and the subsequent oxidative stress. In this paper, we examined the effects of hypoxia (93% N(2):2% O(2):5% CO(2), v/v/v) on rat cortical synaptosomes by evaluating modifications o

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a55fc731533de5cca866204d76a1a946
http://hdl.handle.net/11365/3690

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Role of intracellular Ca2+ and calmodulin/MAP kinase kinase/extracellular signal-regulated protein kinase signalling pathway in the mitogenic and antimitogenic effect of nitric oxide in glia- and neurone-derived cell lines

Autor: Maria Frosini, Antonella Meini, Mitri Palmi, Gian Paolo Pessina, Julian Blanco Garcia, Carlo Aldinucci

Publikováno v: The European journal of neuroscience. 23(7)

To elucidate the mechanism of cell growth regulation by nitric oxide (NO) and the role played in it by Ca2+, we studied the relationship among intracellular Ca2+ concentration ([Ca2+]i), mitogen-activated protein kinases [extracellular signal-regulat

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6d96a31860e43e8b0c83a3066e067cde
https://pubmed.ncbi.nlm.nih.gov/16623825

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Potentiation of intracellular Ca2+ mobilization by hypoxia-induced NO generation in rat brain striatal slices and human astrocytoma U-373 MG cells and its involvement in tissue damage

Autor: Antonella, Meini, Alberto, Benocci, Maria, Frosini, Gian Pietro, Sgaragli, Julian Blanco, Garcia, Gian Paolo, Pessina, Carlo, Aldinucci, Mitri, Palmi

Publikováno v: The European journal of neuroscience. 17(4)

The relationship between nitric oxide (NO) and intracellular Ca2+ in hypoxic-ischemic brain damage is not known in detail. Here we used rat striatal slices perfused under low-oxygen and Ca2+-free conditions and cultured human astrocytoma cells incuba

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::ce459ceb9258aeb66f4c4fe41bb9454f
https://pubmed.ncbi.nlm.nih.gov/12603259

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The effect of strong static magnetic field on lymphocytes

Autor: Gianpietro Sgaragli, Gian Paolo Pessina, Carlo Aldinucci, Claudia Bonechi, Claudio Rossi, Antonella Meini, Mitri Palmi, Alberto Benocci, Federica Pessina, Julian Blanco Garcia

We investigated whether static electromagnetic fields (EMFs) at a flux density of 4.75 T, generated by an NMR apparatus (NMRF), could promote movements of Ca2+, cell proliferation, and the eventual production of proinflammatory cytokines in human per

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0a1baf3c40e5e198d459e8fcbd5beedf
http://hdl.handle.net/11365/34185

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The effect of exposure to high flux density static and pulsed magnetic fields on lymphocyte function

Autor: Julian Blanco Garcia, Carlo Aldinucci, Antonella Meini, Mitri Palmi, Alberto Benocci, Gianpietro Sgaragli, Gian Paolo Pessina, Claudia Bonechi, Claudio Rossi, Federica Pessina

We investigated whether a combination of static electromagnetic field (EMF) at a flux density of 4.75 T together with pulsed EMF at a flux density of 0.7 mT generated by an NMR apparatus (NMRF), could promote movements of Ca(2+), cell proliferation,

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::15b7d037e07209bd3311f3d9adf6b990
http://hdl.handle.net/11365/34130

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