Enhanced relaxivity of GdIII-complexes with HP-DO3A-like ligands upon the activation of the intramolecular catalysis of the prototropic exchange

Autor: Eliana Gianolio, Attila Forgács, Silvio Aime, Franco Fedeli, Luciano Lattuada, Alberto Fringuello Mingo, Zsolt Baranyai, Paolo Minazzi, Giovanni B. Giovenzana, Attila Bényei, Dávid Horváth, Sonia Colombo Serra

Publikováno v: Inorganic Chemistry Frontiers. 8:1500-1510

Gadolinium(III) complexes have been employed for more than 30 years as contrast agents in magnetic resonance imaging (MRI). In order to further improve the diagnostic accuracy of enhanced magnetic resonance images or to provide comparable enhancement

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f77b1fff735ea38365518683edc7d92b
https://doi.org/10.1039/d0qi01333a

Gd-AAZTA-MADEC, an improved blood pool agent for DCE-MRI studies on mice on 1 T scanners

Autor: Lorena Consolino, Giovanni B. Giovenzana, Simonetta Geninatti-Crich, Silvio Aime, Paolo Minazzi, Francesca Arena, Dario Livio Longo

Publikováno v: Biomaterials 75 (2016): 47–57. doi:10.1016/j.biomaterials.2015.10.012
info:cnr-pdr/source/autori:Longo, Dario Livio; Arena, Francesca; Consolino, Lorena; Minazzi, Paolo; Geninatti-Crich, Simonetta; Giovenzana, Giovanni Battista; Aime, Silvio;/titolo:Gd-AAZTA-MADEC, an improved blood pool agent for DCE-MRI studies on mice on 1 T scanners/doi:10.1016%2Fj.biomaterials.2015.10.012/rivista:Biomaterials/anno:2016/pagina_da:47/pagina_a:57/intervallo_pagine:47–57/volume:75

A novel MRI blood-pool contrast agent (Gd-AAZTA-MADEC) has been compared with established blood pool agents for tumor contrast enhanced images and angiography. Synthesis, relaxometric properties, albumin binding affinity and pharmacokinetic profiles

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bc11f1437fc390109832f1e027a44192
http://hdl.handle.net/2318/1557817

Influence of a novel, versatile bifunctional chelator on theranostic properties of a minigastrin analogue

Autor: Milos Petrik, Elisabeth von Guggenberg, Joachim Pfister, Giovanni B. Giovenzana, Luigi Aloj, Paolo Minazzi, Dominik Summer, Christine Rangger, Clemens Decristoforo

Publikováno v: EJNMMI Research

Background 6-[Bis(carboxymethyl)amino]-1,4-bis(carboxymethyl)-6-methyl-1,4-diazepane (AAZTA ) is a promising chelator with potential advantages over 1,4,7,10-tetraazacyclododecane-1,4,7,10-tetraacetic acid (DOTA) for radiopharmaceutical applications.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::37fa24add3592ec8c0f07ea42c34969a
https://www.repository.cam.ac.uk/handle/1810/287181

A serendipitous one-pot synthesis of the octahydro-2H-pyrazino[1,2-a]pyrazine core.

Autor: Maestri, Claudio, Minazzi, Paolo, Grell, Toni, Colombo, Valentina, Lattuada, Luciano, Giovenzana, Giovanni B., Travagin, Fabio

Publikováno v: Chemical Communications; 9/11/2024, Vol. 60 Issue 70, p9428-9431, 4p

Enhanced relaxivity of Gd^III-complexes with HP-DO3A-like ligands upon the activation of the intramolecular catalysis of the prototropic exchange.

Autor: Lattuada, Luciano, Horváth, Dávid, Colombo Serra, Sonia, Fringuello Mingo, Alberto, Minazzi, Paolo, Bényei, Attila, Forgács, Attila, Fedeli, Franco, Gianolio, Eliana, Aime, Silvio, Giovenzana, Giovanni B., Baranyai, Zsolt

Publikováno v: Inorganic Chemistry Frontiers; 3/21/2021, Vol. 8 Issue 6, p1500-1510, 11p