Zobrazeno 1 - 10
of 29
pro vyhledávání: '"Paolo Medini"'
Publikováno v:
iScience, Vol 26, Iss 9, Pp 107545- (2023)
Summary: Little is known about estrous effects on brain microcircuits. We examined the accessory olfactory bulb (AOB) in vivo, in anesthetized naturally cycling females, as model microcircuit receiving coital somatosensory information. Whole-cell rec
Externí odkaz:
https://doaj.org/article/52389d887e924b018b781f788c754472
Autor:
Stylianos Papaioannou, Paolo Medini
Publikováno v:
Frontiers in Neuroscience, Vol 16 (2022)
The holy grail for every neurophysiologist is to conclude a causal relationship between an elementary behaviour and the function of a specific brain area or circuit. Our effort to map elementary behaviours to specific brain loci and to further manipu
Externí odkaz:
https://doaj.org/article/1e28930bea294cc59e6ffcfeb8055e73
Publikováno v:
PLoS ONE, Vol 8, Iss 12, p e82044 (2013)
Monocular deprivation (MD) during development leads to a dramatic loss of responsiveness through the deprived eye in primary visual cortical neurons, and to degraded spatial vision (amblyopia) in all species tested so far, including rodents. Such los
Externí odkaz:
https://doaj.org/article/fbcdb33c802f4195802106bbd84cb5b3
Multiphoton microscopy allows measurement of network activity as well as the manipulation of cell type specific or functionally identified neuronal subpopulations with optogenetic holographic stimulation. When neurons co-express an activity reporter
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1b2cf2e3747d24f0b97a46f814415cd4
https://doi.org/10.1101/2022.08.06.503049
https://doi.org/10.1101/2022.08.06.503049
Publikováno v:
Journal of Psychiatry & Neuroscience : JPN
Background: Auditory hallucinations (which occur when the distinction between thoughts and perceptions is blurred) are common in psychotic disorders. The orbitofrontal cortex (OFC) may be implicated, because it receives multiple inputs, including sou
Autor:
Lars Thelander, Andrei Chabes, Jonas von Hofsten, Paolo Lorenzon, Per Stål, Phong Tran, Paolo Medini, Sushma Sharma, Paulina H. Wanrooij, Anna Karin Nilsson, Anna-Karin Olofsson
Publikováno v:
Journal of Biological Chemistry. 294:15889-15897
The building blocks of DNA, dNTPs, can be produced de novo or can be salvaged from deoxyribonucleosides. However, to what extent the absence of de novo dNTP production can be compensated for by the salvage pathway is unknown. Here, we eliminated de n
Publikováno v:
Journal of neuroscience methods. 362
BACKGROUNDBrain visual circuits are often studied in vivo by imaging Ca2+ indicators with green-shifted emission spectra. Polychromatic white visual stimuli have a spectrum that partially overlaps indicators’ emission spectra, resulting in signific
Autor:
Rajendra Kumar, Kazutoshi Kasho, Ikenna Obi, Kristoffer Brännström, Rabindra Nath Das, Parham L. Pourbozorgi, James E. Mason, Jan Jamroskovic, Nasim Sabouri, Mattias Hedenström, Mara Doimo, Sjoerd Wanrooij, Sebastian Sulis Sato, Marco Deiana, Erik Chorell, Almaz Akhunzianov, Paolo Medini, Daniel Öhlund, Karam Chand
Publikováno v:
Journal of the American Chemical Society
The signal transducer and activator of transcription 3 (STAT3) protein is a master regulator of most key hallmarks and enablers of cancer, including cell proliferation and the response to DNA damage. G-Quadruplex (G4) structures are four-stranded non
Autor:
Paolo Medini, Bojana Kokinovic
Publikováno v:
The Journal of Physiology. 596:1949-1964
Recovery after stroke is mediated by plastic changes largely occurring in the lesion periphery. However, little is known about the microcircuit changes underlying recovery, the extent to which peri ...
Autor:
Erica Barini, Maria Grazia Spillantini, Laura Gasparini, Paolo Medini, Nadia Mazzaro, Michel Goedert
Publikováno v:
The Journal of neuroscience : the official journal of the Society for Neuroscience. 36(7)
Tauopathies are neurodegenerative diseases characterized by intraneuronal inclusions of hyperphosphorylated tau protein and abnormal expression of brain-derived neurotrophic factor (BDNF), a key modulator of neuronal survival and function. The severi