Zobrazeno 1 - 10
of 118
pro vyhledávání: '"Paolo Massobrio"'
Publikováno v:
APL Bioengineering, Vol 8, Iss 3, Pp 036112-036112-15 (2024)
Three-dimensionality (3D) was proven essential for developing reliable models for different anatomical compartments and many diseases. However, the neuronal compartment still poses a great challenge as we still do not understand precisely how the bra
Externí odkaz:
https://doaj.org/article/1d5feb0471d5409ea5fd062488b24b5e
Autor:
Valerio Barabino, Ilaria Donati della Lunga, Francesca Callegari, Letizia Cerutti, Fabio Poggio, Mariateresa Tedesco, Paolo Massobrio, Martina Brofiga
Publikováno v:
Frontiers in Cellular Neuroscience, Vol 18 (2024)
IntroductionThe human brain is an intricate structure composed of interconnected modular networks, whose organization is known to balance the principles of segregation and integration, enabling rapid information exchange and the generation of coheren
Externí odkaz:
https://doaj.org/article/06b891fd629e42469a0de27d83e71436
Autor:
Martina Brofiga, Serena Losacco, Fabio Poggio, Roberta Arianna Zerbo, Marco Milanese, Paolo Massobrio, Bruno Burlando
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-15 (2023)
Abstract Understanding the brain functioning is essential for governing brain processes with the aim of managing pathological network dysfunctions. Due to the morphological and biochemical complexity of the central nervous system, the development of
Externí odkaz:
https://doaj.org/article/85c39331c5a748fb8ed1aa7193003595
Publikováno v:
Frontiers in Cellular Neuroscience, Vol 17 (2023)
IntroductionThe goal of this work is to prove the relevance of the experimental model (in vitro neuronal networks in this study) when drug-delivery testing is performed.MethodsWe used dissociated cortical and hippocampal neurons coupled to Micro-Elec
Externí odkaz:
https://doaj.org/article/b5a948bd658c42b893bd3edcb56282b8
Publikováno v:
PLoS Computational Biology, Vol 19, Iss 2, p e1010825 (2023)
Nowadays, in vitro three-dimensional (3D) neuronal networks are becoming a consolidated experimental model to overcome most of the intrinsic limitations of bi-dimensional (2D) assemblies. In the 3D environment, experimental evidence revealed a wider
Externí odkaz:
https://doaj.org/article/d41da5622f6d46498615f0734364b335
Autor:
Martina Brofiga, Paolo Massobrio
Publikováno v:
Frontiers in Neuroscience, Vol 16 (2022)
Externí odkaz:
https://doaj.org/article/f98e1f03c67f415cb6ea98c97f0dabf1
Autor:
Fabio Poggio, Martina Brofiga, Mariateresa Tedesco, Paolo Massobrio, Enrico Adriano, Maurizio Balestrino
Publikováno v:
Biomolecules, Vol 13, Iss 1, p 74 (2022)
The creatine precursor Guanidinoacetic Acid (GAA) accumulates in the genetic deficiency of the GuanidinoAcetate Methyl Transferase (GAMT) enzyme and it is believed to cause the seizures that often occur in this condition. However, evidence that it is
Externí odkaz:
https://doaj.org/article/712142eef1b84eecb0d6ad0d0096d16a
Autor:
Michela Chiappalone, Vinicius R. Cota, Marta Carè, Mattia Di Florio, Romain Beaubois, Stefano Buccelli, Federico Barban, Martina Brofiga, Alberto Averna, Francesco Bonacini, David J. Guggenmos, Yannick Bornat, Paolo Massobrio, Paolo Bonifazi, Timothée Levi
Publikováno v:
Brain Sciences, Vol 12, Iss 11, p 1578 (2022)
Neuroprostheses are neuroengineering devices that have an interface with the nervous system and supplement or substitute functionality in people with disabilities. In the collective imagination, neuroprostheses are mostly used to restore sensory or m
Externí odkaz:
https://doaj.org/article/f4ea3082818d4b3982710b93360553d1
Publikováno v:
Frontiers in Neuroscience, Vol 15 (2021)
The identification of the organization principles on the basis of the brain connectivity can be performed in terms of structural (i.e., morphological), functional (i.e., statistical), or effective (i.e., causal) connectivity. If structural connectivi
Externí odkaz:
https://doaj.org/article/9669f97adedf485494727fa28095c754
Autor:
Stefano Buccelli, Yannick Bornat, Ilaria Colombi, Matthieu Ambroise, Laura Martines, Valentina Pasquale, Marta Bisio, Jacopo Tessadori, Przemysław Nowak, Filippo Grassia, Alberto Averna, Mariateresa Tedesco, Paolo Bonifazi, Francesco Difato, Paolo Massobrio, Timothée Levi, Michela Chiappalone
Publikováno v:
iScience, Vol 19, Iss , Pp 402-414 (2019)
Summary: Recent advances in bioelectronics and neural engineering allowed the development of brain machine interfaces and neuroprostheses, capable of facilitating or recovering functionality in people with neurological disability. To realize energy-e
Externí odkaz:
https://doaj.org/article/497f0d879f4f40329e8f51ffc5993185