Zobrazeno 1 - 10
of 144
pro vyhledávání: '"Paolo Macor"'
Autor:
Davide Busato, Sara Capolla, Paolo Durigutto, Monica Mossenta, Sara Bozzer, Daniele Sblattero, Paolo Macor, Michele Dal Bo, Giuseppe Toffoli
Publikováno v:
Journal of Translational Medicine, Vol 21, Iss 1, Pp 1-13 (2023)
Abstract Background Pancreatic ductal adenocarcinoma (PDAC) is one of the most aggressive cancers with a very low survival rate at 5 years. The use of chemotherapeutic agents results in only modest prolongation of survival and is generally associated
Externí odkaz:
https://doaj.org/article/da4516817faf461f9882e4337173d4b5
Autor:
Sara Capolla, Federico Colombo, Luca De Maso, Prisca Mauro, Paolo Bertoncin, Thilo Kähne, Alexander Engler, Luis Núñez, Ruben Spretz, Gustavo Larsen, Michele Dal Bo, Giuseppe Toffoli, Paolo Macor
Publikováno v:
Journal of Nanobiotechnology, Vol 21, Iss 1, Pp 1-20 (2023)
Abstract Background Nanoparticles represent one of the most important innovations in the medical field. Among nanocarriers, polymeric nanoparticles (PNPs) attracted much attention due to their biodegradability, biocompatibility, and capacity to incre
Externí odkaz:
https://doaj.org/article/62e01429a3cc4ca498bd80beda0dc175
Publikováno v:
Frontiers in Pharmacology, Vol 14 (2023)
Antibody-Drug Conjugates (ADCs) represent an innovative class of potent anti-cancer compounds that are widely used in the treatment of hematologic malignancies and solid tumors. Unlike conventional chemotherapeutic drug-based therapies, that are main
Externí odkaz:
https://doaj.org/article/9f8c921bb7654c3988f94fd5aa170677
Targeted chitosan nanobubbles as a strategy to down-regulate microRNA-17 into B-cell lymphoma models
Autor:
Sara Capolla, Monica Argenziano, Sara Bozzer, Tiziana D’Agaro, Tamara Bittolo, Luigina De Leo, Tarcisio Not, Davide Busato, Michele Dal Bo, Giuseppe Toffoli, Roberta Cavalli, Valter Gattei, Riccardo Bomben, Paolo Macor
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
IntroductionMicroRNAs represent interesting targets for new therapies because their altered expression influences tumor development and progression. miR-17 is a prototype of onco-miRNA, known to be overexpressed in B-cell non-Hodgkin lymphoma (B-NHL)
Externí odkaz:
https://doaj.org/article/700fa76819c64673b3c87d0dc34aa22c
Autor:
Ann-Kathrin Meinshausen, Jacqueline Färber, Sebastian Illiger, Paolo Macor, Christoph H. Lohmann, Jessica Bertrand
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
BackgroundCulture-negative periprosthetic joint infections (PJI) are often false diagnosed as aseptic implant failure leading to unnecessary revision surgeries due to repeated infections. A marker to increase the security of e PJI diagnosis is theref
Externí odkaz:
https://doaj.org/article/bff115a1a8434436a51448cf1e861f19
Autor:
Claudia Grossi, Nagaja Capitani, Marisa Benagiano, Cosima Tatiana Baldari, Chiara Della Bella, Paolo Macor, Francesco Tedesco, Maria Orietta Borghi, Norma Maugeri, Mario Milco D’Elios, Pier Luigi Meroni
Publikováno v:
Frontiers in Immunology, Vol 13 (2023)
Antiphospholipid syndrome (APS) is a systemic autoimmune disorder characterized by recurrent vascular thrombosis and miscarriages in the absence of known causes. Antibodies against phospholipid-binding proteins (aPL) are pathogenic players in both cl
Externí odkaz:
https://doaj.org/article/9f15eca05e6845d489f4edd9b0b9ff04
Autor:
Paolo Macor, Paolo Durigutto, Monica Argenziano, Kate Smith-Jackson, Sara Capolla, Valeria Di Leonardo, Kevin Marchbank, Valerio Stefano Tolva, Fabrizio Semeraro, Concetta T. Ammollo, Mario Colucci, Roberta Cavalli, Pierluigi Meroni, Francesco Tedesco
Publikováno v:
Haematologica, Vol 108, Iss 7 (2022)
β2-glycoprotein I (β2-GPI) is a serum protein widely recognized as the main target of antibodies present in patients with antiphospholipid syndrome (APS). β2-GPI binds to activated endothelial cells, platelets and leukocytes, key players in thromb
Externí odkaz:
https://doaj.org/article/98d50d9c03c845fe962d09eab9d61bcc
Publikováno v:
Pharmaceutics, Vol 14, Iss 12, p 2605 (2022)
Nanoparticles (NPs) are versatile candidates for nanomedical applications due to their unique physicochemical properties. However, their clinical applicability is hindered by their undesirable recognition by the immune system and the consequent immun
Externí odkaz:
https://doaj.org/article/c4da296dfeec40ce802fb40d9545c97d
Autor:
Sara Bozzer, Luca De Maso, Maria Cristina Grimaldi, Sara Capolla, Michele Dal Bo, Giuseppe Toffoli, Paolo Macor
Publikováno v:
Biomedicines, Vol 10, Iss 9, p 2252 (2022)
The use of zebrafish (ZF) embryos as an in vivo model is increasingly attractive thanks to different features that include easy handling, transparency, and the absence of adaptive immunity until 4–6 weeks. These factors allow the development of xen
Externí odkaz:
https://doaj.org/article/f248b637741f42a099a224e48cca9e4f
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 18, p 10279 (2022)
Pancreatic ductal adenocarcinoma (PDAC) accounts for 90% of all pancreatic cancers, with a 5-year survival rate of 7% and 80% of patients diagnosed with advanced or metastatic malignancies. Despite recent advances in diagnostic testing, surgical tech
Externí odkaz:
https://doaj.org/article/45f856c9f5ed4b3c922270a46cd10d65