Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Paolo Giovanelli"'
Autor:
Michael J. P. Crowley, Bhavneet Bhinder, Geoffrey J. Markowitz, Mitchell Martin, Akanksha Verma, Tito A. Sandoval, Chang-Suk Chae, Shira Yomtoubian, Yang Hu, Sahil Chopra, Diamile A. Tavarez, Paolo Giovanelli, Dingcheng Gao, Timothy E. McGraw, Nasser K. Altorki, Olivier Elemento, Juan R. Cubillos-Ruiz, Vivek Mittal
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-16 (2023)
The IRE1α-XBP1 arm of the unfolded protein response (UPR) has been associated with immunosuppression and cancer progression. Here the authors show that IRE1α-XBP1 activation is associated with poor overall survival in patients with non-small cell l
Externí odkaz:
https://doaj.org/article/77b087499a044dd7be6eee31431dbce9
Autor:
Juan R. Cubillos-Ruiz, Anniina Färkkilä, Alan D. D'Andrea, David Pépin, Dmitriy Zamarin, E. Alfonso Romero-Sandoval, Kevin Holcomb, Franck J. Barrat, Minkyung Song, Andrew V. Kossenkov, Julia Casado, Vidyanath Chaudhary, Chen Tan, Alexander Emmanuelli, Camilla Salvagno, Deepika Awasthi, Paolo Giovanelli, Eun Sil Park, Sung-Min Hwang, Tito A. Sandoval, Chang-Suk Chae
Lysophosphatidic acid (LPA) is a bioactive lipid enriched in the tumor microenvironment of immunosuppressive malignancies such as ovarian cancer. Although LPA enhances the tumorigenic attributes of cancer cells, the immunomodulatory activity of this
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::33ede94b80b3ea8712940a7fc1e24d87
https://doi.org/10.1158/2159-8290.c.6549535.v1
https://doi.org/10.1158/2159-8290.c.6549535.v1
Autor:
Juan R. Cubillos-Ruiz, Anniina Färkkilä, Alan D. D'Andrea, David Pépin, Dmitriy Zamarin, E. Alfonso Romero-Sandoval, Kevin Holcomb, Franck J. Barrat, Minkyung Song, Andrew V. Kossenkov, Julia Casado, Vidyanath Chaudhary, Chen Tan, Alexander Emmanuelli, Camilla Salvagno, Deepika Awasthi, Paolo Giovanelli, Eun Sil Park, Sung-Min Hwang, Tito A. Sandoval, Chang-Suk Chae
Supplementary Figure from Tumor-Derived Lysophosphatidic Acid Blunts Protective Type I Interferon Responses in Ovarian Cancer
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::583f85e3fff585198f9a8ef99aa0b051
https://doi.org/10.1158/2159-8290.22541002.v1
https://doi.org/10.1158/2159-8290.22541002.v1
Autor:
Chang-Suk Chae, Tito A. Sandoval, Sung-Min Hwang, Eun Sil Park, Paolo Giovanelli, Deepika Awasthi, Camilla Salvagno, Alexander Emmanuelli, Chen Tan, Vidyanath Chaudhary, Julia Casado, Andrew V. Kossenkov, Minkyung Song, Franck J. Barrat, Kevin Holcomb, E. Alfonso Romero-Sandoval, Dmitriy Zamarin, David Pépin, Alan D. D'Andrea, Anniina Färkkilä, Juan R. Cubillos-Ruiz
Publikováno v:
Cancer Discov
Lysophosphatidic acid (LPA) is a bioactive lipid enriched in the tumor microenvironment of immunosuppressive malignancies such as ovarian cancer. Although LPA enhances the tumorigenic attributes of cancer cells, the immunomodulatory activity of this
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::52362ad2096ab4e9bdf05e3a05314eb2
https://europepmc.org/articles/PMC9357054/
https://europepmc.org/articles/PMC9357054/
Autor:
Colleen M. Lau, Paolo Giovanelli, Sam Sheppard, Joseph C. Sun, Hyunu Kim, Sara Violante, Endi K. Santosa, Ming Li, Justin R. Cross
Publikováno v:
Cell reports
SUMMARY Natural killer (NK) cells are cytotoxic lymphocytes capable of rapid cytotoxicity, cytokine secretion, and clonal expansion. To sustain such energetically demanding processes, NK cells must increase their metabolic capacity upon activation. H
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::798759e86ffc327a750f7637f87a9cec
https://pubmed.ncbi.nlm.nih.gov/34077737
https://pubmed.ncbi.nlm.nih.gov/34077737
Autor:
Kotha Subbaramaiah, Sahil Chopra, Minkyung Song, Leandro Jimenez, Philip J. Kingsley, E. Alfonso Romero-Sandoval, Sara Alonso, Juan R. Cubillos-Ruiz, Andrew V. Kossenkov, Paolo Giovanelli, Takao Iwawaki, Andrew J. Dannenberg, Mariano Sánchez Crespo, Miriam M. Fonseca, Tito A. Sandoval, Chang-Suk Chae, Silvia Gutierrez, Chen Tan, Lawrence J. Marnett, Laurie H. Glimcher, Perla Abigail Alvarado-Vazquez
Publikováno v:
Digital.CSIC. Repositorio Institucional del CSIC
instname
instname
Inositol-requiring enzyme 1[α] (IRE1[α])–X-box binding protein spliced (XBP1) signaling maintains endoplasmic reticulum (ER) homeostasis while controlling immunometabolic processes. Yet, the physiological consequences of IRE1a–XBP1 activation i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cd7f2bd6b82231140cea9d66122e0c3f
https://doi.org/10.1126/science.aau6499
https://doi.org/10.1126/science.aau6499
Publikováno v:
Trends in immunology. 40(8)
Dendritic cells (DCs) are fundamental for the initiation and maintenance of immune responses against malignant cells. Despite the unique potential of DCs to elicit robust anticancer immunity, the tumor microenvironment poses a variety of challenges t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6ef0763f6892eaa9e6ffd098dc44d68f
https://pubmed.ncbi.nlm.nih.gov/31301952
https://pubmed.ncbi.nlm.nih.gov/31301952