Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Paolo Giannetti"'
Autor:
Marios Politis, Nayana Lahiri, Flavia Niccolini, Paul Su, Kit Wu, Paolo Giannetti, Rachael I. Scahill, Federico E. Turkheimer, Sarah J. Tabrizi, Paola Piccini
Publikováno v:
Neurobiology of Disease, Vol 83, Iss , Pp 115-121 (2015)
Previous studies have shown activation of the immune system and altered immune response in Huntington's disease (HD) gene carriers. Here, we hypothesized that peripheral and central immune responses could be concurrent pathophysiological events and r
Externí odkaz:
https://doaj.org/article/db7b12c187ca4b4c806a502eb4484aa6
Autor:
Marios Politis, Nayana Lahiri, Flavia Niccolini, Paul Su, Kit Wu, Paolo Giannetti, Rachael I. Scahill, Federico E. Turkheimer, Sarah J. Tabrizi, Paola Piccini
Publikováno v:
Neurobiology of Disease, Vol 98, Iss , Pp 162- (2017)
Externí odkaz:
https://doaj.org/article/67c4d01f02fd430ba0b6496493270cc4
Autor:
Paolo Giannetti, Marios Politis, Paul Su, Federico Turkheimer, Omar Malik, Shiva Keihaninejad, Kit Wu, Richard Reynolds, Richard Nicholas, Paola Piccini
Publikováno v:
Neurobiology of Disease, Vol 65, Iss , Pp 203-210 (2014)
The pathophysiological correlates and the contribution to persisting disability of hypointense T1-weighted MRI lesions, black holes (BH), in multiple sclerosis (MS) are still unclear. In order to study the in vivo functional correlates of this MRI fi
Externí odkaz:
https://doaj.org/article/607d8734529c4cd79b30812c63ba5cb9
Autor:
Sarah J. Tabrizi, Marios Politis, N Lahiri, Rachael I. Scahill, Paola Piccini, Paul Su, Kit Wu, Federico Turkheimer, Paolo Giannetti, Flavia Niccolini
Publikováno v:
Neurobiology of Disease, Vol 83, Iss, Pp 115-121 (2015)
Previous studies have shown activation of the immune system and altered immune response in Huntington's disease (HD) gene carriers. Here, we hypothesized that peripheral and central immune responses could be concurrent pathophysiological events and r
Autor:
Kit Wu, Paul Su, Richard Nicholas, Marios Politis, Paola Piccini, Richard Reynolds, Paolo Giannetti, Omar Malik, Federico Turkheimer, Shiva Keihaninejad
Publikováno v:
Neurobiology of Disease, Vol 65, Iss, Pp 203-210 (2014)
The pathophysiological correlates and the contribution to persisting disability of hypointense T1-weighted MRI lesions, black holes (BH), in multiple sclerosis (MS) are still unclear. In order to study the in vivo functional correlates of this MRI fi
Autor:
Federico Turkheimer, Omar Malik, Richard Nicholas, Paul M. Matthews, Paul Su, Kit Wu, Paola Piccini, Adam D. Waldman, Marios Politis, Shiva Keihaninejad, Paolo Giannetti, Richard Reynolds
Publikováno v:
Neurology. 79:523-530
Objective: Activated microglia are thought to play a major role in cortical gray matter (GM) demyelination in multiple sclerosis (MS). Our objective was to evaluate microglial activation in cortical GM of patients with MS in vivo and to explore its r
Autor:
Richard Reynolds, Shiva Keihaninejad, Federico Turkheimer, Kit Wu, Paolo Giannetti, Paul Su, Paola Piccini, Richard Nicholas, Omar Malik, Marios Politis, Adam D. Waldman
The most accurate predictor of the subsequent development of multiple sclerosis in clinically isolated syndrome is the presence of lesions at magnetic resonance imaging. We used in vivo positron emission tomography with (11)C-(R)-PK11195, a biomarker
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::15c674a36be6ce4eba142d1a7f949df7
http://hdl.handle.net/10044/1/22090
http://hdl.handle.net/10044/1/22090
Autor:
Paul M. Matthews, Richard Nicholas, Omar Malik, Olga Ciccarelli, Qi Guo, Mayca Onega, Paola Piccini, David R. Owen, Alessandro Colasanti, Stuart C.G. Rison, Nils Muhlert, Paolo A. Muraro, Charlotte Thomas, Roger N. Gunn, Rexford D. Newbould, Eugenii A. Rabiner, Paolo Giannetti
Publikováno v:
Journal of nuclear medicine : official publication, Society of Nuclear Medicine. 55(7)
PET radioligand binding to the 18-kD translocator protein (TSPO) in the brains of patients with multiple sclerosis (MS) primarily reflects activated microglia and macrophages. We previously developed genetic stratification for accurate quantitative e
Paolo Giannetti,1 Flavia Niccolini,2 Richard Nicholas11Centre for Neurosciences, Division of Experimental Medicine, Department of Medicine, Imperial College, London, UK; 2University of Rome “Sapienza”, Department of Neurology and Psychiatry, Rome
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a1305f1ae5fb448e2e25fef6646e2367
https://europepmc.org/articles/PMC6065565/
https://europepmc.org/articles/PMC6065565/
Publikováno v:
Drug Design, Development and Therapy
The emergence of oral disease-modifying therapies in multiple sclerosis (MS) will have a significant impact on the evolving scenario of immunomodulatory treatments in MS where current therapies are all injectable. Reducing relapses in trials translat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2c3fd01c319d42733b557f5828357dba
http://resolver.sub.uni-goettingen.de/purl?gs-1/8154
http://resolver.sub.uni-goettingen.de/purl?gs-1/8154