Výsledky vyhledávání - "Paolo Dotto, G"

Akademický článek

Integration of Notch1 and calcineurin/NFAT signaling pathway in keratinocyte growth and differentiation control.

Autor: Mammukari, C., Tommasi di Vignano, A., Sharov, A.A., Neilson, J., Havrda, M.C., Roop, D.R., Botchkarev, Vladimir A., Crabtree, G.R., Paolo Dotto, G

The Notch and Calcineurin/NFAT pathways have both been implicated in control of keratinocyte differentiation. Induction of the p21WAF1/Cip1 gene by Notch 1 activation in differentiating keratinocytes is associated with direct targeting of the RBP-J¿

Externí odkaz: http://hdl.handle.net/10454/3660

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Akademický článek

Nuclear lamin A/C phosphorylation by loss of androgen receptor leads to cancer-associated fibroblast activation.

Autor: Ghosh, Soumitra, Isma, Jovan, Ostano, Paola, Mazzeo, Luigi, Toniolo, Annagiada, Das, Monalisa, White, Joni R., Simon, Christian, Paolo Dotto, G.

Publikováno v: Nature Communications; 9/12/2024, Vol. 15 Issue 1, p1-22, 22p

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Akademický článek

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CSL controls telomere maintenance and genome stability in human dermal fibroblasts

Autor: Bottoni, Giulia, Katarkar, Atul, Tassone, Beatrice, Ghosh, Soumitra, Clocchiatti, Andrea, Goruppi, Sandro, Bordignon, Pino, Jafari, Paris, Tordini, Fabio, Lunardi, Thomas, Hoetzenecker, Wolfram, Neel, Victor, Lingner, Joachim, Paolo Dotto, G.

Publikováno v: Nature Communications
Nature Communications, Vol 10, Iss 1, Pp 1-15 (2019)

Genomic instability is a hallmark of cancer. Whether it also occurs in Cancer Associated Fibroblasts (CAFs) remains to be carefully investigated. Loss of CSL/RBP-Jκ, the effector of canonical NOTCH signaling with intrinsic transcription repressive f

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::44737051098d5c3efdb16f7294f89ab6
http://europepmc.org/articles/PMC6715699

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