Zobrazeno 1 - 10
of 54
pro vyhledávání: '"Paolo Carrega"'
Autor:
Alessia Calabrò, Fabiana Drommi, Claudia De Pasquale, Giuseppe Navarra, Paolo Carrega, Irene Bonaccorsi, Guido Ferlazzo, Stefania Campana
Publikováno v:
Gut Microbes, Vol 16, Iss 1 (2024)
Growing evidence highlights the pivotal role of RORγt-innate lymphoid cells (ILCs) in the establishment of antitumor immune response and in enhancing tumor sensitivity to immunotherapy. Noteworthy, type 3 ILCs (ILC3s) have been recently acknowledged
Externí odkaz:
https://doaj.org/article/e88c4b1ea4454d27a50898e99a8082b3
Autor:
Monica Parodi, Simonetta Astigiano, Paolo Carrega, Gabriella Pietra, Chiara Vitale, Laura Damele, Melania Grottoli, Maria de la Luz Guevara Lopez, Riccardo Ferracini, Giulia Bertolini, Ilaria Roato, Massimo Vitale, Paola Orecchia
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
Since the first studies, the mouse models have provided crucial support for the most important discoveries on NK cells, on their development, function, and circulation within normal and tumor tissues. Murine tumor models were initially set to study m
Externí odkaz:
https://doaj.org/article/0309575181784972bcbc9dc6dafb0a48
Autor:
Carlo Genova, Chiara Dellepiane, Paolo Carrega, Sara Sommariva, Guido Ferlazzo, Paolo Pronzato, Rosaria Gangemi, Gilberto Filaci, Simona Coco, Michela Croce
Publikováno v:
Frontiers in Immunology, Vol 12 (2022)
In the last decade, the treatment of non-small cell lung cancer (NSCLC) has been revolutionized by the introduction of immune checkpoint inhibitors (ICI) directed against programmed death protein 1 (PD-1) and its ligand (PD-L1), or cytotoxic T lympho
Externí odkaz:
https://doaj.org/article/fdf9dff0eeab48d6bc67db88fdefbeb5
Autor:
Selene Ottonello, Carlo Genova, Irene Cossu, Vincenzo Fontana, Erika Rijavec, Giovanni Rossi, Federica Biello, Maria Giovanna Dal Bello, Marco Tagliamento, Angela Alama, Simona Coco, Simona Boccardo, Irene Vanni, Guido Ferlazzo, Lorenzo Moretta, Francesco Grossi, Maria Cristina Mingari, Paolo Carrega, Gabriella Pietra
Publikováno v:
Frontiers in Immunology, Vol 11 (2020)
Immune checkpoint blockade represents a major breakthrough in advanced non-small cell lung cancer (NSCLC) therapy. However, success is limited to a subset of patients and there is a critical need to identify robust biomarkers associated with clinical
Externí odkaz:
https://doaj.org/article/d2bc4156441047f087b7ab4cc39af254
Autor:
Ana Raykova, Paolo Carrega, Frank M. Lehmann, Robert Ivanek, Vanessa Landtwing, Isaak Quast, Jan D. Lünemann, Daniela Finke, Guido Ferlazzo, Obinna Chijioke, Christian Münz
Publikováno v:
Blood Advances, Vol 1, Iss 27, Pp 2679-2691 (2017)
Abstract: Type 3 innate lymphoid cells (ILC3s) fulfill protective functions at mucosal surfaces via cytokine production. Although their plasticity to become ILC1s, the innate counterparts of type 1 helper T cells, has been described previously, we re
Externí odkaz:
https://doaj.org/article/719cb6bbebc148f887d5b58086f1fa60
Autor:
Irene Bonaccorsi, Domenico Spinelli, Claudia Cantoni, Chiara Barillà, Narayana Pipitò, Claudia De Pasquale, Daniela Oliveri, Riccardo Cavaliere, Paolo Carrega, Filippo Benedetto, Guido Ferlazzo
Publikováno v:
Frontiers in Immunology, Vol 10 (2019)
A wide array of immune cells, including lymphocytes, is known to be present and to play a pathogenetic role in atherosclerotic lesions. However, limited information is currently available regarding the presence of Natural Killer (NK) cell subsets wit
Externí odkaz:
https://doaj.org/article/a113861ab8cd4fb2a92a58bd827c573e
Autor:
Roberta Castriconi, Paolo Carrega, Alessandra Dondero, Francesca Bellora, Beatrice Casu, Stefano Regis, Guido Ferlazzo, Cristina Bottino
Publikováno v:
Frontiers in Immunology, Vol 9 (2018)
A large body of data shows that Natural Killer (NK) cells are immune effectors exerting a potent cytolytic activity against tumors and virus infected cells. The discovery and characterization of several inhibitory and activating receptors unveiled mo
Externí odkaz:
https://doaj.org/article/dd83e38de9a34bcda308bc5eb0177a91
Autor:
Irene Bonaccorsi, Claudia Cantoni, Paolo Carrega, Daniela Oliveri, Gabrielle Lui, Romana Conte, Michele Navarra, Riccardo Cavaliere, Elisabetta Traggiai, Marco Gattorno, Alberto Martini, Maria Cristina Mingari, Alessandro Moretta, Guido Ferlazzo
Publikováno v:
PLoS ONE, Vol 5, Iss 11, p e15080 (2010)
Plasmacytoid dendritic cells (pDCs) are a subset of dendritic cells endowed with the capacity of producing large amounts of IFNα. Here we show that the Leukocyte-Associated Ig-like Receptor-1 (LAIR-1) is abundantly expressed on pDCs (the highest exp
Externí odkaz:
https://doaj.org/article/8ad6751fa98a4c419b42d9951c4951a3
Autor:
Paolo Carrega, Gaetana Pezzino, Paola Queirolo, Irene Bonaccorsi, Michela Falco, Giuseppe Vita, Daniela Pende, Aldo Misefari, Alessandro Moretta, Maria Cristina Mingari, Lorenzo Moretta, Guido Ferlazzo
Publikováno v:
PLoS ONE, Vol 4, Iss 12, p e8132 (2009)
BACKGROUND: Despite Natural Killer (NK) cells were originally defined as effectors of spontaneous cytotoxicity against tumors, extremely limited information is so far available in humans on their capability of killing cancer cells in an autologous se
Externí odkaz:
https://doaj.org/article/26c2d12aa12a4b639b859768316d0533
Autor:
Giacomo Sidoti Migliore, Stefania Campana, Chiara Barberi, Claudia De Pasquale, Gaetana Pezzino, Riccardo Cavaliere, Paola Orecchia, Giovanna Ginestra, Giuseppina Mandalari, Genny Del Zotto, Irene Bonaccorsi, Paolo Carrega, Maria Cristina Mingari, Guido Ferlazzo
Publikováno v:
Journal of Leukocyte Biology. 113:535-540
Polyvalent mechanical bacterial lysate is effective in the prevention of respiratory tract infections, although its mechanism of action is not entirely elucidated. Because epithelial cells constitute the frontline defense against infections, we inves