Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Paolo Cantelmi"'
Autor:
Alexia Mattellone, Dario Corbisiero, Paolo Cantelmi, Giulia Martelli, Chiara Palladino, Alessandra Tolomelli, Walter Cabri, Lucia Ferrazzano
Publikováno v:
Molecules, Vol 28, Iss 20, p 7183 (2023)
The growing applications of peptide-based therapeutics require the development of efficient protocols from the perspective of an industrial scale-up. T3P® (cyclic propylphosphonic anhydride) promotes amidation in the solution-phase through a biomime
Externí odkaz:
https://doaj.org/article/8e2861d3dee14e1aaff9503098aa8e8c
Autor:
Walter Cabri, Paolo Cantelmi, Dario Corbisiero, Tommaso Fantoni, Lucia Ferrazzano, Giulia Martelli, Alexia Mattellone, Alessandra Tolomelli
Publikováno v:
Frontiers in Molecular Biosciences, Vol 8 (2021)
Targeting protein-protein interactions (PPIs) has been recently recognized as an emerging therapeutic approach for several diseases. Up today, more than half a million PPI dysregulations have been found to be involved in pathological events. The dyna
Externí odkaz:
https://doaj.org/article/bebbb00d10bc48b8b623ec2bb61e43df
Autor:
Dario Corbisiero, Tommaso Fantoni, Lucia Ferrazzano, Giulia Martelli, Paolo Cantelmi, Alexia Mattellone, Chiara Palladino, Magda Monari, Riccardo Pedrazzani, Alessandra Tolomelli, Walter Cabri
Publikováno v:
ACS Omega. 7:26919-26927
The enantioselective 1,3-dipolar cycloaddition of nitrones and arylpropionaldehydes to generate highly functionalized scaffolds for application in drug discovery was herein investigated. The use of a second-generation MacMillan catalyst as hydrochlor
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8a30e597e4bf4c405804046a1b248384
https://doi.org/10.1021/acsomega.2c03477
https://doi.org/10.1021/acsomega.2c03477
Autor:
Alexia Mattellone, Dario Corbisiero, Lucia Ferrazzano, Paolo Cantelmi, Giulia Martelli, Chiara Palladino, Alessandra Tolomelli, Walter Cabri
Publikováno v:
Green Chemistry. 25:2563-2571
A fast and greensolution-phase peptide synthesis (GSolPPS) via continuous protocol, addressed with propylphosphonic anhydride T3P® as coupling reagent and N-benzyloxycarbonyl-protecting group easily removed by hydrogenation is herein reported.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::822486f6962774f8c2d3dd1c50f3ad29
https://doi.org/10.1039/d3gc00431g
https://doi.org/10.1039/d3gc00431g
Autor:
Lucia Ferrazzano, Martina Catani, Alberto Cavazzini, Giulia Martelli, Dario Corbisiero, Paolo Cantelmi, Tommaso Fantoni, Alexia Mattellone, Chiara De Luca, Simona Felletti, Walter Cabri, Alessandra Tolomelli
Publikováno v:
Green Chemistry. 24:975-1020
Developing greener synthesis processes is an inescapable necessity to transform the industrial landscape, mainly in the pharmaceutical sector, into a long-term, sustainable reality. In this context, the renaissance of peptides as medical treatments,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4791977f33431568cbaafd80d9ada452
https://doi.org/10.1039/d1gc04387k
https://doi.org/10.1039/d1gc04387k
Autor:
Tommaso Fantoni, Antonio Ricci, Marco Mor, Sara Bernardoni, Giulia Martelli, Lucia Ferrazzano, Walter Cabri, Paolo Cantelmi, Federica Vacondio, Alessandra Tolomelli, Francesca Ferlenghi, Dario Corbisiero, Alexia Mattellone
Publikováno v:
Chemsuschem
The identification of a green, versatile, user‐friendly, and efficient methodology is necessary to facilitate the use of Heck‐Cassar‐Sonogashira (HCS) cross‐coupling reaction in drug discovery and industrial production in the pharmaceutical s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::359996303448dc26df8c1631221f9527
https://doi.org/10.1002/cssc.202100623
https://doi.org/10.1002/cssc.202100623
Autor:
Giulia Martelli, Alexia Mattellone, Walter Cabri, Chiara Palladino, Paolo Cantelmi, Lucia Ferrazzano, Marco Macis, Dario Corbisiero, Alessandra Tolomelli, Tommaso Fantoni, Antonio Ricci
Publikováno v:
Green Chemistry. 23:8096-8107
Solid Phase Peptide Synthesis (SPPS) is a key technology for the production of pharmaceutical grade peptides, although it represents the worst modality in the pharma segment when considering its Process Mass Intensity (PMI). Consequently, academic an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b883f3b53f62a52669edc35634060b37
https://doi.org/10.1039/d1gc02634h
https://doi.org/10.1039/d1gc02634h
Autor:
Paolo Cantelmi, Giulia Martelli, Dario Corbisiero, Tommaso Fantoni, Walter Cabri, Alessandra Tolomelli, Alexia Mattellone, Lucia Ferrazzano
Publikováno v:
Frontiers in Molecular Biosciences, Vol 8 (2021)
Frontiers in Molecular Biosciences
Frontiers in Molecular Biosciences
Targeting protein-protein interactions (PPIs) has been recently recognized as an emerging therapeutic approach for several diseases. Up today, more than half a million PPI dysregulations have been found to be involved in pathological events. The dyna
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0e992013a99d4e41ff46be2372f71995
https://doi.org/10.3389/fmolb.2021.697586
https://doi.org/10.3389/fmolb.2021.697586
Autor:
Tommaso Fantoni, Dario Corbisiero, Walter Cabri, Paolo Cantelmi, Giulia Martelli, Francesca Ferlenghi, Federica Vacondio, Marco Mor, Alessandra Tolomelli, Antonio Ricci, Alexia Mattellone, Lucia Ferrazzano
The investigation of new green biogenic pyrrolidinones as alternative solvents to N,N-dimethylformamide (DMF) for solid phase peptide synthesis (SPPS) led to the identification of N-octyl pyrrolidone (NOP) as the best candidate. NOP showed good perfo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::09ab7da685e9c83cea23a9447fa6ad80
http://hdl.handle.net/11585/822026
http://hdl.handle.net/11585/822026
