Zobrazeno 1 - 10
of 150
pro vyhledávání: '"Paolo A Muraro"'
Autor:
Gavin Giovannoni, Stephen J Walters, David Paling, Olga Ciccarelli, Cindy Cooper, Eli Silber, Martin Duddy, Hannah Hunter, David Hunt, Basil Sharrack, Paul Gallagher, Ian Galea, Richard Nicholas, Annalena Venneri, Neil Robertson, Carolyn Young, Jeremy Hobart, David Rog, Ben Turner, Muhammad Saif, Azza Ismail, Gavin Brittain, John A Snowden, Diana Papaioannou, Alasdair J Coles, Gordon Mazibrada, Neil Scolding, Maruthi Vinjam, Matthew Bursnall, Claire Rice, Ian Pomeroy, Majid Kazmi, Esmaeil Nikfekr, Kim Orchard, Thushan de Silva, Jennifer Petrie, Elisa Roldan, Caroline Besley, Kate E M Duffy, Rachel Glover, Katie Hullock, Colette Beecher, Ian Gabriel, Charalampia Kyriakou, Andy Peniket, Paolo A Muraro, Amy Publicover, Andy Clark, Charles Crawley, Eleni Tholouli, Fran Kinsella, Gabriele De Luca, Jeff Davies, Jenny Byrne, Keith Campbell, Leonora Finisku, Simon Bulley, Vic Campbell
Publikováno v:
BMJ Open, Vol 14, Iss 2 (2024)
Introduction Autologous haematopoietic stem cell transplantation (aHSCT) is increasingly used as treatment for patients with active multiple sclerosis (MS), typically after failure of disease-modifying therapies (DMTs). A recent phase III trial, ‘M
Externí odkaz:
https://doaj.org/article/cef35258b9e74bbbaf15d925d8681e1d
Autor:
Courtney A Bishop, Rexford D Newbould, Jean SZ Lee, Lesley Honeyfield, Rebecca Quest, Alessandro Colasanti, Rehiana Ali, Miriam Mattoscio, Antonio Cortese, Richard Nicholas, Paul M. Matthews, Paolo A Muraro, Adam D Waldman
Publikováno v:
NeuroImage: Clinical, Vol 13, Iss C, Pp 9-15 (2017)
Age of onset in multiple sclerosis (MS) exerts an influence on the course of disease. This study examined whether global and regional brain volumes differed between “younger” and “older” onset MS subjects who were matched for short disease du
Externí odkaz:
https://doaj.org/article/bd04b4f8f670432099a5b7ce73c30af9
Autor:
Mireia Sospedra, Yingdong Zhao, Harald zur Hausen, Paolo A Muraro, Christa Hamashin, Ethel-Michele de Villiers, Clemencia Pinilla, Roland Martin
Publikováno v:
PLoS Pathogens, Vol 1, Iss 4, p e41 (2005)
The triggers of autoimmune diseases such as multiple sclerosis (MS) remain elusive. Epidemiological studies suggest that common pathogens can exacerbate and also induce MS, but it has been difficult to pinpoint individual organisms. Here we demonstra
Externí odkaz:
https://doaj.org/article/8098eda2efd14c3a829fb87aa15fcfdf
Autor:
Maria Teresa Cencioni, Angela Genchi, Gavin Brittain, Thushan I. de Silva, Basil Sharrack, John Andrew Snowden, Tobias Alexander, Raffaella Greco, Paolo A. Muraro
Publikováno v:
Frontiers in Immunology, Vol 12 (2022)
Multiple sclerosis (MS) is a central nervous system (CNS) disorder, which is mediated by an abnormal immune response coordinated by T and B cells resulting in areas of inflammation, demyelination, and axonal loss. Disease-modifying treatments (DMTs)
Externí odkaz:
https://doaj.org/article/36f300aadf6b4e6f99c4ac7b7e411581
Autor:
Sophie A. H. Jacobs, Paolo A. Muraro, Maria T. Cencioni, Sarah Knowles, James H. Cole, Richard Nicholas
Publikováno v:
Frontiers in Neurology, Vol 12 (2022)
Background: Magnetic Resonance Imaging (MRI) analysis method “brain-age” paradigm could offer an intuitive prognostic metric (brain-predicted age difference: brain-PAD) for disability in Multiple Sclerosis (MS), reflecting structural brain health
Externí odkaz:
https://doaj.org/article/7ed8e2dbfab04bc69b99882a05a47409
Autor:
Tobias Alexander, John A. Snowden, Joachim Burman, Hyun-Dong Chang, Nicoletta Del Papa, Dominique Farge, James O. Lindsay, Florent Malard, Paolo A. Muraro, Rosamaria Nitti, Azucena Salas, Basil Sharrack, Mohamad Mohty, Raffaella Greco
Publikováno v:
Frontiers in Oncology, Vol 11 (2021)
Over the past decades, hematopoietic stem cell transplantation (HSCT) has been evolving as specific treatment for patients with severe and refractory autoimmune diseases (ADs), where mechanistic studies have provided evidence for a profound immune re
Externí odkaz:
https://doaj.org/article/f5ccbc09aed1483bb7994e04a50eb978
Autor:
Roberta Amoriello, Maria Chernigovskaya, Victor Greiff, Alberto Carnasciali, Luca Massacesi, Alessandro Barilaro, Anna M. Repice, Tiziana Biagioli, Alessandra Aldinucci, Paolo A. Muraro, David A. Laplaud, Andreas Lossius, Clara Ballerini
Publikováno v:
EBioMedicine, Vol 68, Iss , Pp 103429- (2021)
Background: T cells play a key role in the pathogenesis of multiple sclerosis (MS), a chronic, inflammatory, demyelinating disease of the central nervous system (CNS). Although several studies recently investigated the T-cell receptor (TCR) repertoir
Externí odkaz:
https://doaj.org/article/9548b214c40f43b3ae8bd667decfb8cd
Autor:
Antonio Uccelli, Alice Laroni, Lou Brundin, Michel Clanet, Oscar Fernandez, Seyed Massood Nabavi, Paolo A. Muraro, Roberto S. Oliveri, Ernst W. Radue, Johann Sellner, Per Soelberg Sorensen, Maria Pia Sormani, Jens Thomas Wuerfel, Mario A. Battaglia, Mark S. Freedman, on behalf of the MESEMS study group
Publikováno v:
Trials, Vol 20, Iss 1, Pp 1-13 (2019)
Abstract Background Multiple sclerosis (MS) is an inflammatory disease of the central nervous system with a degenerative component, leading to irreversible disability. Mesenchymal stem cells (MSC) have been shown to prevent inflammation and neurodege
Externí odkaz:
https://doaj.org/article/cecb42ab3b814fa7b6f5dace14d6516b
Autor:
Fiona Roberts, Helen Hobbs, Helen Jessop, Cristina Bozzolini, Joachim Burman, Raffaella Greco, Azza Ismail, Majid Kazmi, Kirill Kirgizov, Gianluigi Mancardi, Susan Mawson, Paolo A. Muraro, Mathieu Puyade, Riccardo Saccardi, Barbara Withers, Bregje Verhoeven, Basil Sharrack, John A. Snowden
Publikováno v:
Frontiers in Neurology, Vol 11 (2020)
Autologous haematopoietic stem cell transplantation (AHSCT) is increasingly used to treat people with multiple sclerosis (MS). Supported by an evolving evidence base, AHSCT can suppress active inflammation in the central nervous system and induce lon
Externí odkaz:
https://doaj.org/article/b9f26c1551774dd488ef6e7c10130eba
Autor:
Paolo A. Muraro
Publikováno v:
Science. 380:470-471
Autologous hematopoietic stem cell transplantation is effective, but mechanisms are elusive