Zobrazeno 1 - 10
of 338
pro vyhledávání: '"Paolo Rovero"'
Autor:
Francesca Nuti, Feliciana Real Fernández, Mirko Severi, Rita Traversi, Vassilios Fanos, Maria Elisabeth Street, Paola Palanza, Paolo Rovero, Anna Maria Papini
Publikováno v:
Molecules, Vol 29, Iss 22, p 5434 (2024)
Exposure to endocrine-disrupting chemicals (EDCs) is inevitable, and growing scientific evidence indicates that even very low doses can negatively impact human health, particularly during pregnancy and the neonatal period. As part of the European pro
Externí odkaz:
https://doaj.org/article/1f1dfaa3144b45179c5544ede3d3471a
Autor:
Francesca Nuti, Maud Larregola, Agnieszka Staśkiewicz, Bernhard Retzl, Nataša Tomašević, Lorenzo Macchia, Maria E. Street, Michał Jewgiński, Olivier Lequin, Rafal Latajka, Paolo Rovero, Christian W. Gruber, Michael Chorev, Anna Maria Papini
Publikováno v:
Journal of Enzyme Inhibition and Medicinal Chemistry, Vol 38, Iss 1 (2023)
Oxytocin (OT) is a neurohypophyseal peptide hormone containing a disulphide-bridged pseudocyclic conformation. The biomedical use of OT peptides is limited amongst others by disadvantageous pharmacokinetic parameters. To increase the stability of OT
Externí odkaz:
https://doaj.org/article/5e89b8ca7f1645cab06fcfd921debf44
Autor:
Patrycja Ledwoń, Waldemar Goldeman, Katarzyna Hałdys, Michał Jewgiński, Greta Calamai, Joanna Rossowska, Anna Maria Papini, Paolo Rovero, Rafał Latajka
Publikováno v:
Journal of Enzyme Inhibition and Medicinal Chemistry, Vol 38, Iss 1 (2023)
The development of skin-care products is recently growing. Cosmetic formulas containing active ingredients with proven efficacy, namely cosmeceuticals, are based on various compounds, including peptides. Different whitening agents featuring anti-tyro
Externí odkaz:
https://doaj.org/article/72c5d9c7730f47889829d5a2f1611826
Autor:
Chiara Testa, Anna Maria Papini, Reinhard Zeidler, Daniela Vullo, Fabrizio Carta, Claudiu T. Supuran, Paolo Rovero
Publikováno v:
Journal of Enzyme Inhibition and Medicinal Chemistry, Vol 37, Iss 1, Pp 592-596 (2022)
We report for the first time Antibody-Drug-Conjugates (ADCs) containing human (h) Carbonic Anhydrase (CA; EC 4.2.1.1) directed Monoclonal Antibodies (MAbs) linked to low molecular weight inhibitors of the same enzymes by means of hydrophilic peptide
Externí odkaz:
https://doaj.org/article/94ce2de81c164617ae629512ea83371a
Autor:
Maria Alfreda Stincarelli, Michael Quagliata, Andrea Di Santo, Lorenzo Pacini, Feliciana Real Fernandez, Rosaria Arvia, Silvia Rinaldi, Anna Maria Papini, Paolo Rovero, Simone Giannecchini
Publikováno v:
Virus Research, Vol 334, Iss , Pp 199170- (2023)
Severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) has posed a great concern in human population. To fight coronavirus emergence, we have dissected the conserved amino acid region of the internal fusion peptide in the S2 subunit of Spike gl
Externí odkaz:
https://doaj.org/article/ab4dc02ec3824c52a4b17e9743313b63
Autor:
Hendrik Rusche, Edoardo Marrani, Feliciana Real-Fernandez, Roberta Ponti, Francesco Terzani, Ilaria Maccora, Olivier Monasson, Maria Vincenza Mastrolia, Elisa Peroni, Ilaria Pagnini, Rolando Cimaz, Anna Maria Papini, Gabriele Simonini, Paolo Rovero
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-13 (2021)
Abstract Immune response to biologics treatment, while widely reported, yet fails to correlate with clinical outcomes and assay to assay comparison is often not possible. Hence, we developed a new peptide based-detection assay to stratify pediatric p
Externí odkaz:
https://doaj.org/article/cb1b521c419a45e9849274f9c708bf09
Autor:
Annunziata D'Ercole, Silvia Nistri, Lorenzo Pacini, Alfonso Carotenuto, Federica Santoro, Anna Maria Papini, Ross A. D. Bathgate, Daniele Bani, Paolo Rovero
Publikováno v:
Frontiers in Pharmacology, Vol 13 (2022)
The peptide hormone relaxin (RLX), also available as clinical-grade recombinant protein (serelaxin), holds great promise as a cardiovascular and anti-fibrotic agent but is limited by the pharmacokinetic issues common to all peptide drugs. In this stu
Externí odkaz:
https://doaj.org/article/df68676b7ec8426f970ad17c8d091f2b
Autor:
Agnieszka Staśkiewicz, Michael Quagliata, Feliciana Real-Fernandez, Francesca Nuti, Roberta Lanzillo, Vincenzo Brescia-Morra, Hendrik Rusche, Michal Jewginski, Alfonso Carotenuto, Diego Brancaccio, Rina Aharoni, Ruth Arnon, Paolo Rovero, Rafal Latajka, Anna Maria Papini
Publikováno v:
Frontiers in Chemistry, Vol 10 (2022)
The involvement of Myelin Basic Protein (MBP) in Multiple Sclerosis (MS) has been widely discussed in the literature. This intrinsically disordered protein has an interesting α-helix motif, which can be considered as a conformational epitope. In thi
Externí odkaz:
https://doaj.org/article/c71a478a745049bc9ab1490a141428d9
Autor:
Federico Pratesi, Fosca Errante, Lorenzo Pacini, Irina Charlot Peña-Moreno, Sebastian Quiceno, Alfonso Carotenuto, Saidou Balam, Drissa Konaté, Mahamadou M. Diakité, Myriam Arévalo-Herrera, Andrey V. Kajava, Paolo Rovero, Giampietro Corradin, Paola Migliorini, Anna M. Papini, Sócrates Herrera
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
The currently devastating pandemic of severe acute respiratory syndrome known as coronavirus disease 2019 or COVID-19 is caused by the coronavirus SARS-CoV-2. Both the virus and the disease have been extensively studied worldwide. A trimeric spike (S
Externí odkaz:
https://doaj.org/article/db7a21810d1d45da83786d7e19d42baf
Autor:
Abdouramane Traoré, Merepen A. Guindo, Drissa Konaté, Bourama Traoré, Seidina A. Diakité, Salimata Kanté, Assitan Dembélé, Abdourhamane Cissé, Nathan C. Incandela, Mamoudou Kodio, Yaya I. Coulibaly, Ousmane Faye, Andrey V. Kajava, Federico Pratesi, Paola Migliorini, Anna Maria Papini, Lorenzo Pacini, Paolo Rovero, Fosca Errante, Mahamadou Diakité, Myriam Arevalo-Herrera, Socrates Herrera, Giampietro Corradin, Saidou Balam
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Despite the global interest and the unprecedented number of scientific studies triggered by the COVID-19 pandemic, few data are available from developing and low-income countries. In these regions, communities live under the threat of various transmi
Externí odkaz:
https://doaj.org/article/7e4d704e33184b28aa812537d1dbaa1c