Zobrazeno 1 - 10
of 89
pro vyhledávání: '"Paolo Monaci"'
Autor:
Elena Fattori, Manuela Cappelletti, Paola Lo Surdo, Alessandra Calzetta, Claus Bendtsen, Yan G. Ni, Shilpa Pandit, Ayesha Sitlani, Giuseppe Mesiti, Andrea Carfí, Paolo Monaci
Publikováno v:
Journal of Lipid Research, Vol 53, Iss 8, Pp 1654-1661 (2012)
Successful development of drugs against novel targets crucially depends on reliable identification of the activity of the target gene product in vivo and a clear demonstration of its specific functional role for disease development. Here, we describe
Externí odkaz:
https://doaj.org/article/51478353f5144461a4af522003ffe481
Autor:
Federico Gabrielli, Roberto Salvi, Chiara Garulli, Cristina Kalogris, Serena Arima, Luca Tardella, Paolo Monaci, Serenella M Pupa, Elda Tagliabue, Maura Montani, Elena Quaglino, Lorenzo Stramucci, Claudia Curcio, Cristina Marchini, Augusto Amici
Publikováno v:
PLoS ONE, Vol 8, Iss 3, p e58358 (2013)
We developed a new phage-display based approach, the Large Fragment Phage Display (LFPD), that can be used for mapping conformational epitopes on target molecules of immunological interest. LFPD uses a simplified and more effective phage-display appr
Externí odkaz:
https://doaj.org/article/d9045c217e2d416c967eca4705e368b1
Autor:
Cristina Marchini, Federico Gabrielli, Manuela Iezzi, Santa Zenobi, Maura Montani, Lucia Pietrella, Cristina Kalogris, Anna Rossini, Valentina Ciravolo, Lorenzo Castagnoli, Elda Tagliabue, Serenella M Pupa, Piero Musiani, Paolo Monaci, Sylvie Menard, Augusto Amici
Publikováno v:
PLoS ONE, Vol 6, Iss 4, p e18727 (2011)
Several transgenic mice models solidly support the hypothesis that HER2 (ERBB2) overexpression or mutation promotes tumorigenesis. Recently, a HER2 splice variant lacking exon-16 (Δ16HER2) has been detected in human breast carcinomas. This alternati
Externí odkaz:
https://doaj.org/article/edf05977323b4ac0ad6313f164920140
Autor:
Paolo Monaci, Alessandra Luzzago, Claudia Santini, Alessandra De Pra, Mirko Arcuri, Francesca Magistri, Alessandro Bellini, Helenia Ansuini, Maria Ambrosio, Virginia Ammendola, Maria Giulia Bigotti, Agostino Cirillo, Maurizio Nuzzo, Annamaria Assunta Nasti, Philippe Neuner, Laura Orsatti, Monica Pezzanera, Andrea Sbardellati, Giuseppe Silvestre, Paolo Uva, Valentina Viti, Gaetano Barbato, Stefano Colloca, Anna Demartis, Emanuele De Rinaldis, Saverio Giampaoli, Armin Lahm, Fabio Palombo, Fabio Talamo, Alessandra Vitelli, Alfredo Nicosia, Riccardo Cortese
Publikováno v:
PLoS ONE, Vol 3, Iss 1, p e1508 (2008)
A novel and efficient tagArray technology was developed that allows rapid identification of antibodies which bind to receptors with a specific expression profile, in the absence of biological information. This method is based on the cloning of a spec
Externí odkaz:
https://doaj.org/article/3c3718022e194affb1af37c3b9733a76
Autor:
Paolo Monaci, Mehrdad Behmanesh, Isabella Saggio, Majid Sadeghizadeh, Mohammad Khalaj-Kondori
Publikováno v:
The Journal of Gene Medicine. 13:622-631
Background The ability to direct efficiently and specifically carriers toward target cells and express the transgene of interest is a critical step in gene therapy trails. The display of targeting molecules on the surface of phage particles might rep
Autor:
Guido Forni, Arthur Fridman, Gennaro Ciliberto, Irene Pak, Shridar Dharmapuri, Nicola La Monica, Barbara Cipriani, Carmela Mennuni, Giuseppe Mesiti, Paolo Monaci, Claus Bendtsen, Elisa Scarselli, Ansu Bagchi
Publikováno v:
Human Gene Therapy. 19:670-680
The aim of this study was to evaluate the efficacy of genetic vaccination with rat ErbB2 antigen in a therapeutic setting for the BALB-neuT mouse model of mammary carcinoma and to establish immunological correlates with vaccine efficacy. To define an
Autor:
Elda Tagliabue, Serenella M. Pupa, Cristina Marchini, Roberto Salvi, Claudia Curcio, Maura Montani, Luca Tardella, Serena Arima, Elena Quaglino, Cristina Kalogris, Paolo Monaci, Augusto Amici, Chiara Garulli, Federico Gabrielli, Lorenzo Stramucci
Publikováno v:
PLoS ONE
PLoS ONE, Vol 8, Iss 3, p e58358 (2013)
PLoS ONE, Vol 8, Iss 3, p e58358 (2013)
We developed a new phage-display based approach, the Large Fragment Phage Display (LFPD), that can be used for mapping conformational epitopes on target molecules of immunological interest. LFPD uses a simplified and more effective phage-display appr
Autor:
Guido Forni, Barbara Cipriani, Maurizio Nuzzo, Paolo Monaci, Pasquale Gallo, Daniele Maldini, Sridhar Dharmapuri
Publikováno v:
International Journal of Cancer. 120:574-584
The transforming rat HER2/neu oncogene (neu), when embedded in the genome of transgenic BALB/c (neuT) mice, provokes the development of an invasive carcinoma in each of their 10 mammary glands. We used the neuT mice model system to evaluate the immun
Publikováno v:
Journal of Virology. 77:11094-11104
In spite of its broad host range, adenovirus type 5 (Ad5) transduces a number of clinically relevant tissues and cell types inefficiently, mostly because of low expression of the coxsackievirus-adenovirus receptor (CAR). To improve gene transfer to s
Autor:
Lorena Urbanelli, Sylvie Ménard, Rosaria Orlandi, Chiara Ronchini, Laura Fontana, Paolo Monaci
Publikováno v:
Journal of Molecular Biology. 313:965-976
Screening a random peptide library displayed on phage as fusion to the major capsid protein pVIII identified a ligand binding the human epidermal growth factor receptor 2 (HER2) specifically. By mutating the sequence of this ligand, a “secondary”