Surface properties of the seas of Titan as revealed by Cassini mission bistatic radar experiments

Autor: Valerio Poggiali, Giancorrado Brighi, Alexander G. Hayes, Phil D. Nicholson, Shannon MacKenzie, Daniel E. Lalich, Léa E. Bonnefoy, Kamal Oudrhiri, Ralph D. Lorenz, Jason M. Soderblom, Paolo Tortora, Marco Zannoni

Publikováno v: Nature Communications, Vol 15, Iss 1, Pp 1-10 (2024)

Abstract Saturn’s moon Titan was explored by the Cassini spacecraft from 2004 to 2017. While Cassini revealed a lot about this Earth-like world, its radar observations could only provide limited information about Titan’s liquid hydrocarbons seas

Externí odkaz: https://doaj.org/article/82c52dbcbf05419f99eb6bcc9e089f05

An Efficient Method for Vault Nanoparticle Conjugation with Finely Adjustable Amounts of Antibodies and Small Molecules

Autor: Giulia Tomaino, Camilla Pantaleoni, Annalisa D’Urzo, Carlo Santambrogio, Filippo Testa, Matilde Ciprandi, Davide Cotugno, Gianni Frascotti, Marco Vanoni, Paolo Tortora

Publikováno v: International Journal of Molecular Sciences, Vol 25, Iss 12, p 6629 (2024)

Vaults are eukaryotic ribonucleoproteins consisting of 78 copies of the major vault protein (MVP), which assemble into a nanoparticle with an about 60 nm volume-based size, enclosing other proteins and RNAs. Regardless of their physiological role(s),

Externí odkaz: https://doaj.org/article/dd830891f6234f00a1e9aab9e41d6ef3

Achievement of the Planetary Defense Investigations of the Double Asteroid Redirection Test (DART) Mission

Autor: Nancy L. Chabot, Andrew S. Rivkin, Andrew F. Cheng, Olivier S. Barnouin, Eugene G. Fahnestock, Derek C. Richardson, Angela M. Stickle, Cristina A. Thomas, Carolyn M. Ernst, R. Terik Daly, Elisabetta Dotto, Angelo Zinzi, Steven R. Chesley, Nicholas A. Moskovitz, Brent W. Barbee, Paul Abell, Harrison F. Agrusa, Michele T. Bannister, Joel Beccarelli, Dmitriy L. Bekker, Megan Bruck Syal, Bonnie J. Buratti, Michael W. Busch, Adriano Campo Bagatin, Joseph P. Chatelain, Sidney Chocron, Gareth S. Collins, Luca Conversi, Thomas M. Davison, Mallory E. DeCoster, J. D. Prasanna Deshapriya, Siegfried Eggl, Raymond C. Espiritu, Tony L. Farnham, Marin Ferrais, Fabio Ferrari, Dora Föhring, Oscar Fuentes-Muñoz, Igor Gai, Carmine Giordano, David A. Glenar, Edward Gomez, Dawn M. Graninger, Simon F. Green, Sarah Greenstreet, Pedro H. Hasselmann, Isabel Herreros, Masatoshi Hirabayashi, Marek Husárik, Simone Ieva, Stavro L. Ivanovski, Samuel L. Jackson, Emmanuel Jehin, Martin Jutzi, Ozgur Karatekin, Matthew M. Knight, Ludmilla Kolokolova, Kathryn M. Kumamoto, Michael Küppers, Fiorangela La Forgia, Monica Lazzarin, Jian-Yang Li, Tim A. Lister, Ramin Lolachi, Michael P. Lucas, Alice Lucchetti, Robert Luther, Rahil Makadia, Elena Mazzotta Epifani, Jay McMahon, Gianmario Merisio, Colby C. Merrill, Alex J. Meyer, Patrick Michel, Marco Micheli, Alessandra Migliorini, Kate Minker, Dario Modenini, Fernando Moreno, Naomi Murdoch, Brian Murphy, Shantanu P. Naidu, Hari Nair, Ryota Nakano, Cyrielle Opitom, Jens Ormö, J. Michael Owen, Maurizio Pajola, Eric E. Palmer, Pasquale Palumbo, Paolo Panicucci, Laura M. Parro, Jason M. Pearl, Antti Penttilä, Davide Perna, Elisabeta Petrescu, Petr Pravec, Sabina D. Raducan, K. T. Ramesh, Ryan Ridden-Harper, Juan L. Rizos, Alessandro Rossi, Nathan X. Roth, Agata Rożek, Benjamin Rozitis, Eileen V. Ryan, William H. Ryan, Paul Sánchez, Toni Santana-Ros, Daniel J. Scheeres, Peter Scheirich, Cem Berk Senel, Colin Snodgrass, Stefania Soldini, Damya Souami, Thomas S. Statler, Rachel Street, Timothy J. Stubbs, Jessica M. Sunshine, Nicole J. Tan, Gonzalo Tancredi, Calley L. Tinsman, Paolo Tortora, Filippo Tusberti, James D. Walker, C. Dany Waller, Kai Wünnemann, Marco Zannoni, Yun Zhang

Publikováno v: The Planetary Science Journal, Vol 5, Iss 2, p 49 (2024)

NASA's Double Asteroid Redirection Test (DART) mission was the first to demonstrate asteroid deflection, and the mission's Level 1 requirements guided its planetary defense investigations. Here, we summarize DART's achievement of those requirements.

Externí odkaz: https://doaj.org/article/0a519bcd35754cc49681152142d32c4f

Addressing Critical Issues Related to Storage and Stability of the Vault Nanoparticle Expressed and Purified from Komagataella phaffi

Autor: Giulia Tomaino, Camilla Pantaleoni, Diletta Ami, Filomena Pellecchia, Annie Dutriaux, Linda Barbieri, Stefania Garbujo, Antonino Natalello, Paolo Tortora, Gianni Frascotti

Publikováno v: International Journal of Molecular Sciences, Vol 24, Iss 4, p 4214 (2023)

The vault nanoparticle is a eukaryotic assembly consisting of 78 copies of the 99-kDa major vault protein. They generate two cup-shaped symmetrical halves, which in vivo enclose protein and RNA molecules. Overall, this assembly is mainly involved in

Externí odkaz: https://doaj.org/article/a00218998123474bb172d49c55c8ae36

Saporin Toxin Delivered by Engineered Colloidal Nanoparticles Is Strongly Effective against Cancer Cells

Autor: Lucia Salvioni, Filippo Testa, Linda Barbieri, Marco Giustra, Jessica Armida Bertolini, Giulia Tomaino, Paolo Tortora, Davide Prosperi, Miriam Colombo

Publikováno v: Pharmaceutics, Vol 14, Iss 7, p 1517 (2022)

Ribosome-inactivating proteins, including Saporin toxin, have found application in the search for innovative alternative cancer therapies to conventional chemo- and radiotherapy. Saporin’s main mechanism of action involves the inhibition of cytopla

Externí odkaz: https://doaj.org/article/8bb24d31fd374b70b917b6245b825acc