Zobrazeno 1 - 10
of 24
pro vyhledávání: '"Paola Trono"'
Publikováno v:
Journal of Experimental & Clinical Cancer Research, Vol 42, Iss 1, Pp 1-21 (2023)
Abstract In recent years, research focused on the multifaceted landscape and functions of cancer-associated fibroblasts (CAFs) aimed to reveal their heterogeneity and identify commonalities across diverse tumors for more effective therapeutic targeti
Externí odkaz:
https://doaj.org/article/e09281ff7fdb4567b0b0bb9f575a4fa5
Autor:
Sarah Warren, Paola Nisticò, Federico Cappuzzo, Federica Marchesi, Isabella Sperduti, Silvia Carpano, Francesca De Nicola, Frauke Goeman, Lorenzo D'Ambrosio, Vanesa Gregorc, Claudio Tripodo, Vincenzo Russo, Paolo Visca, Francesca Paolini, Paola Trono, Annalisa Tocci, Belinda Palermo, Anna Di Carlo, Daniel D'Andrea, Francesca Di Modugno, Giacomo Corleone, Mariangela Panetta, Silvia Baldari, Paolo Zucali
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 11, Iss 8 (2023)
Background Understanding how cancer signaling pathways promote an immunosuppressive program which sustains acquired or primary resistance to immune checkpoint blockade (ICB) is a crucial step in improving immunotherapy efficacy. Among the pathways th
Externí odkaz:
https://doaj.org/article/fd3fa3f807bf4ff6ad2b89290cb99193
Autor:
Francesca Di Modugno, Cristina Colosi, Paola Trono, Giuseppe Antonacci, Giancarlo Ruocco, Paola Nisticò
Publikováno v:
Journal of Experimental & Clinical Cancer Research, Vol 38, Iss 1, Pp 1-14 (2019)
Abstract Immune checkpoint inhibitor therapy has changed clinical practice for patients with different cancers, since these agents have demonstrated a significant improvement of overall survival and are effective in many patients. However, an intrins
Externí odkaz:
https://doaj.org/article/a9165f00816b4f42b69007752506e0a5
Publikováno v:
Biology, Vol 10, Iss 9, p 913 (2021)
Chronic viral infection and cancer are closely inter-related and are both characterized by profound alteration of tissue homeostasis. The actin cytoskeleton dynamics highly participate in tissue homeostasis and act as a sensor leading to an immune-me
Externí odkaz:
https://doaj.org/article/ecdb02d6037d443b90d0f9506d8bb88c
Publikováno v:
Biomolecules, Vol 11, Iss 2, p 336 (2021)
Human tissues, to maintain their architecture and function, respond to injuries by activating intricate biochemical and physical mechanisms that regulates intercellular communication crucial in maintaining tissue homeostasis. Coordination of the comm
Externí odkaz:
https://doaj.org/article/89b3c3469d934614a56653738e5881fe
Autor:
Francesca Di Modugno, Marcella Mottolese, Lucia DeMonte, Paola Trono, Michele Balsamo, Andrea Conidi, Elisa Melucci, Irene Terrenato, Francesca Belleudi, Maria Rosaria Torrisi, Massimo Alessio, Angela Santoni, Paola Nisticò
Publikováno v:
PLoS ONE, Vol 5, Iss 12, p e15852 (2010)
hMena and the epithelial specific isoform hMena(11a) are actin cytoskeleton regulatory proteins belonging to the Ena/VASP family. EGF treatment of breast cancer cell lines upregulates hMena/hMena(11a) expression and phosphorylates hMena(11a), suggest
Externí odkaz:
https://doaj.org/article/f7093392d49a4d87ba8650698a1ac7d5
Publikováno v:
Biology
Biology, Vol 10, Iss 913, p 913 (2021)
Biology, Vol 10, Iss 913, p 913 (2021)
Simple Summary Actin cytoskeleton is a dynamic subcellular component critical for maintaining cell shape and for elaborating response to any stimulus converging on the cell. Cytoskeleton constantly interfaces with diverse cellular components and affe
Publikováno v:
Biomolecules
Biomolecules, Vol 11, Iss 336, p 336 (2021)
Biomolecules, Vol 11, Iss 336, p 336 (2021)
Human tissues, to maintain their architecture and function, respond to injuries by activating intricate biochemical and physical mechanisms that regulates intercellular communication crucial in maintaining tissue homeostasis. Coordination of the comm
Publikováno v:
Emerging Topics in Life Sciences
Targeting of immune checkpoint blockers (ICBs), such as cytotoxic T-lymphocyte antigen-4 and programmed-death 1/programmed-death ligand 1, has dramatically changed the landscape of cancer treatment. Seeing patients who were refractory to conventional
Autor:
Giancarlo Ruocco, Paola Trono, Francesca Di Modugno, Giuseppe Antonacci, Paola Nisticò, Cristina Colosi
Publikováno v:
Journal of Experimental & Clinical Cancer Research : CR
Journal of Experimental & Clinical Cancer Research, Vol 38, Iss 1, Pp 1-14 (2019)
Journal of Experimental & Clinical Cancer Research, Vol 38, Iss 1, Pp 1-14 (2019)
Immune checkpoint inhibitor therapy has changed clinical practice for patients with different cancers, since these agents have demonstrated a significant improvement of overall survival and are effective in many patients. However, an intrinsic or acq