Zobrazeno 1 - 10
of 27
pro vyhledávání: '"Paola Ruiz Puentes"'
Autor:
Eduardo Ravelo-Nieto, Javier Cifuentes, Paola Ruiz Puentes, Laura Rueda-Gensini, Valentina Quezada, Carlos Ostos, Carolina Muñoz-Camargo, Luis H. Reyes, Alvaro Duarte-Ruiz, Juan C. Cruz
Publikováno v:
Frontiers in Bioengineering and Biotechnology, Vol 11 (2023)
The limited delivery of cargoes at the cellular level is a significant challenge for therapeutic strategies due to the presence of numerous biological barriers. By immobilizing the Buforin II (BUF-II) peptide and the OmpA protein on magnetite nanopar
Externí odkaz:
https://doaj.org/article/d9eb1f2b54ac42f5a8f806466ba26b67
Autor:
Javier Cifuentes, Santiago Cifuentes-Almanza, Paola Ruiz Puentes, Valentina Quezada, Andrés Fernando González Barrios, María-Angélica Calderón-Peláez, Myriam Lucia Velandia-Romero, Marjan Rafat, Carolina Muñoz-Camargo, Sonia L. Albarracín, Juan C. Cruz
Publikováno v:
Frontiers in Bioengineering and Biotechnology, Vol 11 (2023)
Parkinson’s disease (PD) is the second most common neurodegenerative disorder after Alzheimer’s disease. Therefore, development of novel technologies and strategies to treat PD is a global health priority. Current treatments include administratio
Externí odkaz:
https://doaj.org/article/09008c2b741541f4b10190339c16a3d6
Autor:
Paola Ruiz Puentes, Laura Rueda-Gensini, Natalia Valderrama, Isabela Hernández, Cristina González, Laura Daza, Carolina Muñoz-Camargo, Juan C. Cruz, Pablo Arbeláez
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-17 (2022)
Abstract Drug Discovery is an active research area that demands great investments and generates low returns due to its inherent complexity and great costs. To identify potential therapeutic candidates more effectively, we propose protein–ligand wit
Externí odkaz:
https://doaj.org/article/92c4e0ae990b4feea461343e1b0ca929
Autor:
Julian Daniel Torres-Vanegas, Javier Cifuentes, Paola Ruiz Puentes, Valentina Quezada, Andres J. Garcia-Brand, Juan C. Cruz, Luis H. Reyes
Publikováno v:
Frontiers in Chemistry, Vol 10 (2022)
Cell-penetrating agents based on functionalized nanoplatforms have emerged as a promising approach for developing more efficient and multifunctional delivery vehicles for treating various complex diseases that require reaching different intracellular
Externí odkaz:
https://doaj.org/article/78ac5206cf6c4697b998a3637c86223d
Autor:
David Arango, Javier Cifuentes, Paola Ruiz Puentes, Tatiana Beltran, Amaury Bittar, Camila Ocasión, Carolina Muñoz-Camargo, Natasha I. Bloch, Luis H. Reyes, Juan C. Cruz
Publikováno v:
Nanomaterials, Vol 13, Iss 11, p 1782 (2023)
Gene delivery has emerged as a promising alternative to conventional treatment approaches, allowing for the manipulation of gene expression through gene insertion, deletion, or alteration. However, the susceptibility of gene delivery components to de
Externí odkaz:
https://doaj.org/article/0f3c048643414c19aac9884c4525df5b
Autor:
Paola Ruiz Puentes, Maria C. Henao, Javier Cifuentes, Carolina Muñoz-Camargo, Luis H. Reyes, Juan C. Cruz, Pablo Arbeláez
Publikováno v:
Membranes, Vol 12, Iss 7, p 708 (2022)
Antibiotic resistance is a worldwide public health problem due to the costs and mortality rates it generates. However, the large pharmaceutical industries have stopped searching for new antibiotics because of their low profitability, given the rapid
Externí odkaz:
https://doaj.org/article/ec1bfeb581be44a5872ee869ff9ad17d
Autor:
Maria C. Henao, Camila Ocasion, Paola Ruiz Puentes, Cristina González-Melo, Valentina Quezada, Javier Cifuentes, Arnovis Yepes, Juan C. Burgos, Juan C. Cruz, Luis H. Reyes
Publikováno v:
Membranes, Vol 12, Iss 6, p 600 (2022)
At the beginning of 2020, the pandemic caused by the SARS-CoV-2 virus led to the fast sequencing of its genome to facilitate molecular engineering strategies to control the pathogen’s spread. The spike (S) glycoprotein has been identified as the le
Externí odkaz:
https://doaj.org/article/b67b7bff46fa440db31a9098b52a0d0d
Autor:
Paola Ruiz Puentes, Natalia Valderrama, Cristina González, Laura Daza, Carolina Muñoz-Camargo, Juan C Cruz, Pablo Arbeláez
Publikováno v:
PLoS ONE, Vol 16, Iss 4, p e0241728 (2021)
The discovery and development of novel pharmaceuticals is an area of active research mainly due to the large investments required and long payback times. As of 2016, the development of a novel drug candidate required up to $ USD 2.6 billion in invest
Externí odkaz:
https://doaj.org/article/f637bc37b02c4611a93a36ff47ea95af
Autor:
Carlos E. Torres, Javier Cifuentes, Saúl C. Gómez, Valentina Quezada, Kevin A. Giraldo, Paola Ruiz Puentes, Laura Rueda-Gensini, Julian A. Serna, Carolina Muñoz-Camargo, Luis H. Reyes, Johann F. Osma, Juan C. Cruz
Publikováno v:
Pharmaceutics, Vol 14, Iss 2, p 315 (2022)
Magnetite nanoparticles (MNPs) have gained significant attention in several applications for drug delivery. However, there are some issues related to cell penetration, especially in the transport of cargoes that show limited membrane passing. A widel
Externí odkaz:
https://doaj.org/article/3f6680ef67af433391cd700e4345e705
Autor:
Paola Ruiz Puentes, María C. Henao, Carlos E. Torres, Saúl C. Gómez, Laura A. Gómez, Juan C. Burgos, Pablo Arbeláez, Johann F. Osma, Carolina Muñoz-Camargo, Luis H. Reyes, Juan C. Cruz
Publikováno v:
Antibiotics, Vol 9, Iss 12, p 854 (2020)
One of the challenges of modern biotechnology is to find new routes to mitigate the resistance to conventional antibiotics. Antimicrobial peptides (AMPs) are an alternative type of biomolecules, naturally present in a wide variety of organisms, with
Externí odkaz:
https://doaj.org/article/ec31fa0817954515a6c176d970ac394d