Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Paola R. Lev"'
Autor:
Geraldine De Luca, Paola R. Lev, Maria F. Camacho, Nora P. Goette, Federico Sackmann, Miguel A. Castro Ríos, Beatriz Moiraghi, Veronica Cortes Guerrieri, Georgina Bendek, Emiliano Carricondo, Alicia Enrico, Veronica Vallejo, Ana Varela, Marina Khoury, Marina Gutierrez, Irene B. Larripa, Rosana F. Marta, Ana C. Glembotsky, Paula G. Heller
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
Myelofibrosis (MF) is a clonal hematopoietic stem cell disorder classified among chronic myeloproliferative neoplasms, characterized by exacerbated myeloid and megakaryocytic proliferation and bone marrow fibrosis. It is induced by driver (JAK2/CALR/
Externí odkaz:
https://doaj.org/article/5d6f229ff02c42ab976c494419308bc5
Pathogenic mechanisms contributing to thrombocytopenia in patients with systemic lupus erythematosus
Autor:
M. Constanza Baroni Pietto, Paola R. Lev, Ana C. Glembotsky, Cecilia P. Marín Oyarzún, Graciela Gomez, Victoria Collado, Cecilia Pisoni, Ramiro A. Gomez, Matías Grodzielski, Jacqueline Gonzalez, Karina V. Mariño, Paula G. Heller, Nora P. Goette, Rosana F. Marta
Publikováno v:
Platelets, Vol 33, Iss 5, Pp 743-754 (2022)
Systemic lupus erythematosus (SLE) is an autoimmune condition developing thrombocytopenia in about 10–15% of cases, however, mechanisms leading to low platelet count were not deeply investigated in this illness. Here we studied possible causes of t
Externí odkaz:
https://doaj.org/article/6b513b6ff98045f69f1dba0a75e76380
Autor:
Cecilia P. Marín Oyarzún, Ana C. Glembotsky, Nora P. Goette, Paola R. Lev, Geraldine De Luca, María C. Baroni Pietto, Beatriz Moiraghi, Miguel A. Castro Ríos, Angeles Vicente, Rosana F. Marta, Mirta Schattner, Paula G. Heller
Publikováno v:
Frontiers in Immunology, Vol 11 (2020)
Essential thrombocythemia (ET) is comprised among chronic myeloproliferative neoplasms (MPN) and is caused by driver mutations in JAK2, CALR, and MPL, which lead to megakaryocyte proliferation and prominent thrombocytosis. Thrombosis remains the main
Externí odkaz:
https://doaj.org/article/c645814c0eff4aa58503e674a2eb6b47
Autor:
Juan P. Salim, Ana C. Glembotsky, Paola R. Lev, Cecilia P. Marin Oyarzún, Nora P. Goette, Felisa C. Molinas, Rosana F. Marta, Paula G. Heller
Publikováno v:
Platelets, Vol 28, Iss 6, Pp 602-606 (2017)
The SDF-1-CXCR4 axis plays an essential role in the regulation of platelet production, by directing megakaryocyte (MK) migration toward the vascular niche, thus allowing terminal maturation and proplatelet formation, and also regulates platelet funct
Externí odkaz:
https://doaj.org/article/9930007e5cf5435d86432ae6f12f066b
Autor:
Nora P Goette, Ana C Glembotsky, Paola R Lev, Matías Grodzielski, Geraldine Contrufo, Marta S Pierdominici, Yesica R Espasandin, Dardo Riveros, Alejandro J García, Felisa C Molinas, Paula G Heller, Rosana F Marta
Publikováno v:
PLoS ONE, Vol 11, Iss 8, p e0160563 (2016)
Mechanisms leading to decreased platelet count in immune thrombocytopenia (ITP) are heterogeneous. This study describes increased platelet apoptosis involving loss of mitochondrial membrane potential (ΔΨm), caspase 3 activation (aCasp3) and phospha
Externí odkaz:
https://doaj.org/article/bc764d30bd6a4f0e9a65c2e73f793414
Autor:
Nora P. Goette, Francisco R. Borzone, Ailen D. Discianni Lupi, Norma A. Chasseing, María F. Rubio, Mónica A. Costas, Paula G. Heller, Rosana F. Marta, Paola R. Lev
Publikováno v:
Experimental hematology. 107
Bone marrow stromal cells provide a proper environment for the development of hematologic lineages. The incorporation of different stromal cells into in vitro culture systems would be an attractive model to study megakaryopoiesis and thrombopoiesis.
Autor:
Paola R. Lev, Juan P. Salim, Laura I. Kornblihtt, Carlos J. Pirola, Rosana F. Marta, Paula G. Heller, Felisa C. Molinas
Publikováno v:
American Journal of Hematology; Feb2005, Vol. 78 Issue 2, p155-157, 3p